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Journal Abstract Search

139 related items for PubMed ID: 15686936

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  • 6. Synthesis and structure-activity relationship of 4-substituted 2-(2-acetyloxyethyl)-8-(morpholine-4-sulfonyl)pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors.
    Kravchenko DV, Kuzovkova YA, Kysil VM, Tkachenko SE, Maliarchouk S, Okun IM, Balakin KV, Ivachtchenko AV.
    J Med Chem; 2005 Jun 02; 48(11):3680-3. PubMed ID: 15916416
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  • 7. Dipyridyl amides: potent metabotropic glutamate subtype 5 (mGlu5) receptor antagonists.
    Bonnefous C, Vernier JM, Hutchinson JH, Chung J, Reyes-Manalo G, Kamenecka T.
    Bioorg Med Chem Lett; 2005 Feb 15; 15(4):1197-200. PubMed ID: 15686941
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  • 8. Discovery of novel 2-(aminoheteroaryl)-thiazole-5-carboxamides as potent and orally active Src-family kinase p56(Lck) inhibitors.
    Chen P, Norris D, Das J, Spergel SH, Wityak J, Leith L, Zhao R, Chen BC, Pitt S, Pang S, Shen DR, Zhang R, De Fex HF, Doweyko AM, McIntyre KW, Shuster DJ, Behnia K, Schieven GL, Barrish JC.
    Bioorg Med Chem Lett; 2004 Dec 20; 14(24):6061-6. PubMed ID: 15546730
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  • 10. Non-thiol farnesyltransferase inhibitors: N-(4-tolylacetylamino-3-benzoylphenyl)-3-arylfurylacrylic acid amides.
    Mitsch A, Wissner P, Silber K, Haebel P, Sattler I, Klebe G, Schlitzer M.
    Bioorg Med Chem; 2004 Sep 01; 12(17):4585-600. PubMed ID: 15358286
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  • 12. Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation.
    DiMauro EF, Newcomb J, Nunes JJ, Bemis JE, Boucher C, Chai L, Chaffee SC, Deak HL, Epstein LF, Faust T, Gallant P, Gore A, Gu Y, Henkle B, Hsieh F, Huang X, Kim JL, Lee JH, Martin MW, McGowan DC, Metz D, Mohn D, Morgenstern KA, Oliveira-dos-Santos A, Patel VF, Powers D, Rose PE, Schneider S, Tomlinson SA, Tudor YY, Turci SM, Welcher AA, Zhao H, Zhu L, Zhu X.
    J Med Chem; 2008 Mar 27; 51(6):1681-94. PubMed ID: 18321037
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  • 13. Catechin derivatives: specific inhibitor for caspases-3, 7 and 2, and the prevention of apoptosis at the cell and animal levels.
    Katunuma N, Ohashi A, Sano E, Ishimaru N, Hayashi Y, Murata E.
    FEBS Lett; 2006 Feb 06; 580(3):741-6. PubMed ID: 16413020
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  • 14. Discovery of a novel class of reversible non-peptide caspase inhibitors via a structure-based approach.
    Fattorusso R, Jung D, Crowell KJ, Forino M, Pellecchia M.
    J Med Chem; 2005 Mar 10; 48(5):1649-56. PubMed ID: 15743206
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  • 17. Design, synthesis, and biological evaluation of isoquinoline-1,3,4-trione derivatives as potent caspase-3 inhibitors.
    Chen YH, Zhang YH, Zhang HJ, Liu DZ, Gu M, Li JY, Wu F, Zhu XZ, Li J, Nan FJ.
    J Med Chem; 2006 Mar 09; 49(5):1613-23. PubMed ID: 16509578
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  • 19. "Click" synthesis of small-molecule inhibitors targeting caspases.
    Ng SL, Yang PY, Chen KY, Srinivasan R, Yao SQ.
    Org Biomol Chem; 2008 Mar 07; 6(5):844-7. PubMed ID: 18292873
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  • 20. Neuroprotective effects of M826, a reversible caspase-3 inhibitor, in the rat malonate model of Huntington's disease.
    Toulmond S, Tang K, Bureau Y, Ashdown H, Degen S, O'Donnell R, Tam J, Han Y, Colucci J, Giroux A, Zhu Y, Boucher M, Pikounis B, Xanthoudakis S, Roy S, Rigby M, Zamboni R, Robertson GS, Ng GY, Nicholson DW, Flückiger JP.
    Br J Pharmacol; 2004 Feb 07; 141(4):689-97. PubMed ID: 14744804
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