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210 related items for PubMed ID: 15699033

  • 1. Distinct mechanistic roles of calpain and caspase activation in neurodegeneration as revealed in mice overexpressing their specific inhibitors.
    Higuchi M, Tomioka M, Takano J, Shirotani K, Iwata N, Masumoto H, Maki M, Itohara S, Saido TC.
    J Biol Chem; 2005 Apr 15; 280(15):15229-37. PubMed ID: 15699033
    [Abstract] [Full Text] [Related]

  • 2. In vivo role of caspases in excitotoxic neuronal death: generation and analysis of transgenic mice expressing baculoviral caspase inhibitor, p35, in postnatal neurons.
    Tomioka M, Shirotani K, Iwata N, Lee HJ, Yang F, Cole GM, Seyama Y, Saido TC.
    Brain Res Mol Brain Res; 2002 Dec 15; 108(1-2):18-32. PubMed ID: 12480175
    [Abstract] [Full Text] [Related]

  • 3. Marked calpastatin (CAST) depletion in Alzheimer's disease accelerates cytoskeleton disruption and neurodegeneration: neuroprotection by CAST overexpression.
    Rao MV, Mohan PS, Peterhoff CM, Yang DS, Schmidt SD, Stavrides PH, Campbell J, Chen Y, Jiang Y, Paskevich PA, Cataldo AM, Haroutunian V, Nixon RA.
    J Neurosci; 2008 Nov 19; 28(47):12241-54. PubMed ID: 19020018
    [Abstract] [Full Text] [Related]

  • 4. Ischemic neuronal death in the rat hippocampus: the calpain-calpastatin-caspase hypothesis.
    Rami A.
    Neurobiol Dis; 2003 Jul 19; 13(2):75-88. PubMed ID: 12828932
    [Abstract] [Full Text] [Related]

  • 5. Kainate induces AKT, ERK and cdk5/GSK3beta pathway deregulation, phosphorylates tau protein in mouse hippocampus.
    Crespo-Biel N, Canudas AM, Camins A, Pallàs M.
    Neurochem Int; 2007 Jan 19; 50(2):435-42. PubMed ID: 17116346
    [Abstract] [Full Text] [Related]

  • 6. Calpastatin overexpression limits calpain-mediated proteolysis and behavioral deficits following traumatic brain injury.
    Schoch KM, Evans HN, Brelsfoard JM, Madathil SK, Takano J, Saido TC, Saatman KE.
    Exp Neurol; 2012 Aug 19; 236(2):371-82. PubMed ID: 22572592
    [Abstract] [Full Text] [Related]

  • 7. In vivo calpain/caspase cross-talk during 3-nitropropionic acid-induced striatal degeneration: implication of a calpain-mediated cleavage of active caspase-3.
    Bizat N, Hermel JM, Humbert S, Jacquard C, Créminon C, Escartin C, Saudou F, Krajewski S, Hantraye P, Brouillet E.
    J Biol Chem; 2003 Oct 31; 278(44):43245-53. PubMed ID: 12917435
    [Abstract] [Full Text] [Related]

  • 8. Synergistic activation of caspase-3 by m-calpain after neonatal hypoxia-ischemia: a mechanism of "pathological apoptosis"?
    Blomgren K, Zhu C, Wang X, Karlsson JO, Leverin AL, Bahr BA, Mallard C, Hagberg H.
    J Biol Chem; 2001 Mar 30; 276(13):10191-8. PubMed ID: 11124942
    [Abstract] [Full Text] [Related]

  • 9. Downregulation of the calpain inhibitor protein calpastatin by caspases during renal ischemia-reperfusion.
    Shi Y, Melnikov VY, Schrier RW, Edelstein CL.
    Am J Physiol Renal Physiol; 2000 Sep 30; 279(3):F509-17. PubMed ID: 10966930
    [Abstract] [Full Text] [Related]

  • 10. The critical role of calpain versus caspase activation in excitotoxic injury induced by nitric oxide.
    Volbracht C, Chua BT, Ng CP, Bahr BA, Hong W, Li P.
    J Neurochem; 2005 Jun 30; 93(5):1280-92. PubMed ID: 15934947
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  • 12. Cross-talk between calpain and caspase proteolytic systems during neuronal apoptosis.
    Neumar RW, Xu YA, Gada H, Guttmann RP, Siman R.
    J Biol Chem; 2003 Apr 18; 278(16):14162-7. PubMed ID: 12576481
    [Abstract] [Full Text] [Related]

  • 13. Calpains mediate p53 activation and neuronal death evoked by DNA damage.
    Sedarous M, Keramaris E, O'Hare M, Melloni E, Slack RS, Elce JS, Greer PA, Park DS.
    J Biol Chem; 2003 Jul 11; 278(28):26031-8. PubMed ID: 12721303
    [Abstract] [Full Text] [Related]

  • 14. Caspase and calpain substrates: roles in synaptic plasticity and cell death.
    Chan SL, Mattson MP.
    J Neurosci Res; 1999 Oct 01; 58(1):167-90. PubMed ID: 10491581
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  • 17. Involvement of calpain activation in neurodegenerative processes.
    Camins A, Verdaguer E, Folch J, Pallàs M.
    CNS Drug Rev; 2006 Oct 01; 12(2):135-48. PubMed ID: 16958987
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  • 19. Activation of calpain in cultured neurons overexpressing Alzheimer amyloid precursor protein.
    Kuwako K, Nishimura I, Uetsuki T, Saido TC, Yoshikawa K.
    Brain Res Mol Brain Res; 2002 Nov 15; 107(2):166-75. PubMed ID: 12425945
    [Abstract] [Full Text] [Related]

  • 20. 3-[2-[4-(3-Chloro-2-methylphenylmethyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydro-chloride 3.5 hydrate (DY-9760e) is neuroprotective in rat microsphere embolism: role of the cross-talk between calpain and caspase-3 through calpastatin.
    Han F, Shirasaki Y, Fukunaga K.
    J Pharmacol Exp Ther; 2006 May 15; 317(2):529-36. PubMed ID: 16467455
    [Abstract] [Full Text] [Related]

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