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399 related items for PubMed ID: 15708439

  • 1. Age- and region-dependent alterations in Abeta-degrading enzymes: implications for Abeta-induced disorders.
    Caccamo A, Oddo S, Sugarman MC, Akbari Y, LaFerla FM.
    Neurobiol Aging; 2005 May; 26(5):645-54. PubMed ID: 15708439
    [Abstract] [Full Text] [Related]

  • 2. Increased expression of Abeta degrading enzyme IDE in the cortex of transgenic mice with Alzheimer's disease-like neuropathology.
    Vepsäläinen S, Hiltunen M, Helisalmi S, Wang J, van Groen T, Tanila H, Soininen H.
    Neurosci Lett; 2008 Jun 20; 438(2):216-20. PubMed ID: 18455870
    [Abstract] [Full Text] [Related]

  • 3. Abeta-degrading enzymes: modulators of Alzheimer's disease pathogenesis and targets for therapeutic intervention.
    Eckman EA, Eckman CB.
    Biochem Soc Trans; 2005 Nov 20; 33(Pt 5):1101-5. PubMed ID: 16246055
    [Abstract] [Full Text] [Related]

  • 4. Anti-amyloid activity of neprilysin in plaque-bearing mouse models of Alzheimer's disease.
    Mohajeri MH, Kuehnle K, Li H, Poirier R, Tracy J, Nitsch RM.
    FEBS Lett; 2004 Mar 26; 562(1-3):16-21. PubMed ID: 15043995
    [Abstract] [Full Text] [Related]

  • 5. Aβ-degrading enzymes: potential for treatment of Alzheimer disease.
    Miners JS, Barua N, Kehoe PG, Gill S, Love S.
    J Neuropathol Exp Neurol; 2011 Nov 26; 70(11):944-59. PubMed ID: 22002425
    [Abstract] [Full Text] [Related]

  • 6. Neprilysin participates in skeletal muscle regeneration and is accumulated in abnormal muscle fibres of inclusion body myositis.
    Broccolini A, Gidaro T, Morosetti R, Gliubizzi C, Servidei T, Pescatori M, Tonali PA, Ricci E, Mirabella M.
    J Neurochem; 2006 Feb 26; 96(3):777-89. PubMed ID: 16405511
    [Abstract] [Full Text] [Related]

  • 7. Impact of Insulin Degrading Enzyme and Neprilysin in Alzheimer's Disease Biology: Characterization of Putative Cognates for Therapeutic Applications.
    Jha NK, Jha SK, Kumar D, Kejriwal N, Sharma R, Ambasta RK, Kumar P.
    J Alzheimers Dis; 2015 Feb 26; 48(4):891-917. PubMed ID: 26444774
    [Abstract] [Full Text] [Related]

  • 8. Effect of Tong Luo Jiu Nao on Aβ-degrading enzymes in AD rat brains.
    Liu Y, Hua Q, Lei H, Li P.
    J Ethnopharmacol; 2011 Sep 02; 137(2):1035-46. PubMed ID: 21798326
    [Abstract] [Full Text] [Related]

  • 9. Region-specific reduction of A beta-degrading endopeptidase, neprilysin, in mouse hippocampus upon aging.
    Iwata N, Takaki Y, Fukami S, Tsubuki S, Saido TC.
    J Neurosci Res; 2002 Nov 01; 70(3):493-500. PubMed ID: 12391610
    [Abstract] [Full Text] [Related]

  • 10. Metabolic regulation of brain Abeta by neprilysin.
    Iwata N, Tsubuki S, Takaki Y, Shirotani K, Lu B, Gerard NP, Gerard C, Hama E, Lee HJ, Saido TC.
    Science; 2001 May 25; 292(5521):1550-2. PubMed ID: 11375493
    [Abstract] [Full Text] [Related]

  • 11. Antagonist of peroxisome proliferator-activated receptor gamma induces cerebellar amyloid-beta levels and motor dysfunction in APP/PS1 transgenic mice.
    Du J, Sun B, Chen K, Fan L, Wang Z.
    Biochem Biophys Res Commun; 2009 Jul 03; 384(3):357-61. PubMed ID: 19422805
    [Abstract] [Full Text] [Related]

  • 12. Pathogenic accumulation of APP in fast twitch muscle of IBM patients and a transgenic model.
    Sugarman MC, Kitazawa M, Baker M, Caiozzo VJ, Querfurth HW, LaFerla FM.
    Neurobiol Aging; 2006 Mar 03; 27(3):423-32. PubMed ID: 15950323
    [Abstract] [Full Text] [Related]

  • 13. Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease.
    Zhao Z, Xiang Z, Haroutunian V, Buxbaum JD, Stetka B, Pasinetti GM.
    Neurobiol Aging; 2007 Jun 03; 28(6):824-30. PubMed ID: 16769157
    [Abstract] [Full Text] [Related]

  • 14. Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein.
    Farris W, Leissring MA, Hemming ML, Chang AY, Selkoe DJ.
    Biochemistry; 2005 May 03; 44(17):6513-25. PubMed ID: 15850385
    [Abstract] [Full Text] [Related]

  • 15. Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer's brain.
    Wang S, Wang R, Chen L, Bennett DA, Dickson DW, Wang DS.
    J Neurochem; 2010 Oct 03; 115(1):47-57. PubMed ID: 20663017
    [Abstract] [Full Text] [Related]

  • 16. Neuronal neprilysin overexpression is associated with attenuation of Abeta-related spatial memory deficit.
    Poirier R, Wolfer DP, Welzl H, Tracy J, Galsworthy MJ, Nitsch RM, Mohajeri MH.
    Neurobiol Dis; 2006 Dec 03; 24(3):475-83. PubMed ID: 17008108
    [Abstract] [Full Text] [Related]

  • 17. Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1.
    Ohno M, Chang L, Tseng W, Oakley H, Citron M, Klein WL, Vassar R, Disterhoft JF.
    Eur J Neurosci; 2006 Jan 03; 23(1):251-60. PubMed ID: 16420434
    [Abstract] [Full Text] [Related]

  • 18. Leptin inhibits amyloid β-protein degradation through decrease of neprilysin expression in primary cultured astrocytes.
    Yamamoto N, Tanida M, Ono Y, Kasahara R, Fujii Y, Ohora K, Suzuki K, Sobue K.
    Biochem Biophys Res Commun; 2014 Feb 28; 445(1):214-7. PubMed ID: 24508800
    [Abstract] [Full Text] [Related]

  • 19. Metabolism of amyloid-beta peptide and Alzheimer's disease.
    Iwata N, Higuchi M, Saido TC.
    Pharmacol Ther; 2005 Nov 28; 108(2):129-48. PubMed ID: 16112736
    [Abstract] [Full Text] [Related]

  • 20. Cellular distribution of insulin-like growth factor-II/mannose-6-phosphate receptor in normal human brain and its alteration in Alzheimer's disease pathology.
    Kar S, Poirier J, Guevara J, Dea D, Hawkes C, Robitaille Y, Quirion R.
    Neurobiol Aging; 2006 Feb 28; 27(2):199-210. PubMed ID: 16399207
    [Abstract] [Full Text] [Related]

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