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464 related items for PubMed ID: 15708864

  • 1. Functional humanization of an anti-CD30 Fab fragment for the immunotherapy of Hodgkin's lymphoma using an in vitro evolution approach.
    Schlapschy M, Gruber H, Gresch O, Schäfer C, Renner C, Pfreundschuh M, Skerra A.
    Protein Eng Des Sel; 2004 Dec; 17(12):847-60. PubMed ID: 15708864
    [Abstract] [Full Text] [Related]

  • 2. Functional humanization of an anti-CD16 Fab fragment: obstacles of switching from murine {lambda} to human {lambda} or {kappa} light chains.
    Schlapschy M, Fogarasi M, Gruber H, Gresch O, Schäfer C, Aguib Y, Skerra A.
    Protein Eng Des Sel; 2009 Mar; 22(3):175-88. PubMed ID: 19022801
    [Abstract] [Full Text] [Related]

  • 3. Anti-CD30-scFv-Fc-IL-2 antibody-cytokine fusion protein that induces resting NK cells to highly efficient cytolysis of Hodgkin's lymphoma derived tumour cells.
    Heuser C, Guhlke S, Matthies A, Bender H, Barth S, Diehl V, Abken H, Hombach A.
    Int J Cancer; 2004 Jun 20; 110(3):386-94. PubMed ID: 15095304
    [Abstract] [Full Text] [Related]

  • 4. Engineering a humanized bispecific F(ab')2 fragment for improved binding to T cells.
    Rodrigues ML, Shalaby MR, Werther W, Presta L, Carter P.
    Int J Cancer Suppl; 1992 Jun 20; 7():45-50. PubMed ID: 1428403
    [Abstract] [Full Text] [Related]

  • 5. Humanization of a murine monoclonal antibody by simultaneous optimization of framework and CDR residues.
    Wu H, Nie Y, Huse WD, Watkins JD.
    J Mol Biol; 1999 Nov 19; 294(1):151-62. PubMed ID: 10556035
    [Abstract] [Full Text] [Related]

  • 6. Humanization of a highly stable single-chain antibody by structure-based antigen-binding site grafting.
    Villani ME, Morea V, Consalvi V, Chiaraluce R, Desiderio A, Benvenuto E, Donini M.
    Mol Immunol; 2008 May 19; 45(9):2474-85. PubMed ID: 18313757
    [Abstract] [Full Text] [Related]

  • 7. Human anti-CD30 recombinant antibodies by guided phage antibody selection using cell panning.
    Klimka A, Matthey B, Roovers RC, Barth S, Arends JW, Engert A, Hoogenboom HR.
    Br J Cancer; 2000 Jul 19; 83(2):252-60. PubMed ID: 10901379
    [Abstract] [Full Text] [Related]

  • 8. An anti-CD30 single-chain Fv selected by phage display and fused to Pseudomonas exotoxin A (Ki-4(scFv)-ETA') is a potent immunotoxin against a Hodgkin-derived cell line.
    Klimka A, Barth S, Matthey B, Roovers RC, Lemke H, Hansen H, Arends JW, Diehl V, Hoogenboom HR, Engert A.
    Br J Cancer; 1999 Jun 19; 80(8):1214-22. PubMed ID: 10376974
    [Abstract] [Full Text] [Related]

  • 9. Antitumor effects of ricin A chain immunotoxins prepared from intact antibodies and Fab' fragments on solid human Hodgkin's disease tumors in mice.
    Engert A, Martin G, Pfreundschuh M, Amlot P, Hsu SM, Diehl V, Thorpe P.
    Cancer Res; 1990 May 15; 50(10):2929-35. PubMed ID: 1692251
    [Abstract] [Full Text] [Related]

  • 10. Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.
    Fan ZC, Shan L, Goldsteen BZ, Guddat LW, Thakur A, Landolfi NF, Co MS, Vasquez M, Queen C, Ramsland PA, Edmundson AB.
    J Mol Recognit; 1999 May 15; 12(1):19-32. PubMed ID: 10398393
    [Abstract] [Full Text] [Related]

  • 11. An anti-CD30 chimeric receptor that mediates CD3-zeta-independent T-cell activation against Hodgkin's lymphoma cells in the presence of soluble CD30.
    Hombach A, Heuser C, Sircar R, Tillmann T, Diehl V, Pohl C, Abken H.
    Cancer Res; 1998 Mar 15; 58(6):1116-9. PubMed ID: 9515791
    [Abstract] [Full Text] [Related]

  • 12. Bacterial production and functional characterization of the Fab fragment of the murine IgG1/lambda monoclonal antibody cmHsp70.1, a reagent for tumour diagnostics.
    Friedrich L, Stangl S, Hahne H, Küster B, Köhler P, Multhoff G, Skerra A.
    Protein Eng Des Sel; 2010 Apr 15; 23(4):161-8. PubMed ID: 20123884
    [Abstract] [Full Text] [Related]

  • 13. [One amino acid mutation in an anti-CD20 antibody fragment that affects the yield bacterial secretion and the affinity].
    Liu YX, Xiong DS, Fan DM, Shao XF, Xu YF, Zhu ZP, Yang CZ.
    Sheng Wu Gong Cheng Xue Bao; 2003 May 15; 19(3):272-6. PubMed ID: 15969005
    [Abstract] [Full Text] [Related]

  • 14. A novel strategy for generation of monoclonal antibodies from single B cells using rt-PCR technique and in vitro expression.
    Jiang X, Suzuki H, Hanai Y, Wada F, Hitomi K, Yamane T, Nakano H.
    Biotechnol Prog; 2006 May 15; 22(4):979-88. PubMed ID: 16889373
    [Abstract] [Full Text] [Related]

  • 15. Humanization of an anti-human IL-6 mouse monoclonal antibody glycosylated in its heavy chain variable region.
    Sato K, Ohtomo T, Hirata Y, Saito H, Matsuura T, Akimoto T, Akamatsu K, Koishihara Y, Ohsugi Y, Tsuchiya M.
    Hum Antibodies Hybridomas; 1996 May 15; 7(4):175-83. PubMed ID: 9140729
    [Abstract] [Full Text] [Related]

  • 16. Expression, refolding, and ferritin-binding activity of the isolated VL-domain of monoclonal antibody F11.
    Dubnovitsky AP, Kravchuk ZI, Chumanevich AA, Cozzi A, Arosio P, Martsev SP.
    Biochemistry (Mosc); 2000 Sep 15; 65(9):1011-8. PubMed ID: 11042491
    [Abstract] [Full Text] [Related]

  • 17. The anti-CD30 monoclonal antibody SGN-30 promotes growth arrest and DNA fragmentation in vitro and affects antitumor activity in models of Hodgkin's disease.
    Wahl AF, Klussman K, Thompson JD, Chen JH, Francisco LV, Risdon G, Chace DF, Siegall CB, Francisco JA.
    Cancer Res; 2002 Jul 01; 62(13):3736-42. PubMed ID: 12097283
    [Abstract] [Full Text] [Related]

  • 18. Characterization of a chimeric T-cell receptor with specificity for the Hodgkin's lymphoma-associated CD30 antigen.
    Hombach A, Heuser C, Sircar R, Tillmann T, Diehl V, Pohl C, Abken H.
    J Immunother; 1999 Nov 01; 22(6):473-80. PubMed ID: 10570745
    [Abstract] [Full Text] [Related]

  • 19. SDR grafting of a murine antibody using multiple human germline templates to minimize its immunogenicity.
    Gonzales NR, Padlan EA, De Pascalis R, Schuck P, Schlom J, Kashmiri SV.
    Mol Immunol; 2004 Jul 01; 41(9):863-72. PubMed ID: 15261458
    [Abstract] [Full Text] [Related]

  • 20. Production of Fab fragment corresponding to surface protein antigen of Streptococcus mutans serotype c-derived peptide by Escherichia coli and cultured tobacco cells.
    Yano A, Takekoshi M, Morita E, Imai S, Nisizawa T, Hanada N.
    J Biosci Bioeng; 2006 Mar 01; 101(3):251-6. PubMed ID: 16716927
    [Abstract] [Full Text] [Related]

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