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274 related items for PubMed ID: 15713896

  • 1. H-RAS V12-induced radioresistance in HCT116 colon carcinoma cells is heregulin dependent.
    Carón RW, Yacoub A, Zhu X, Mitchell C, Han SI, Sasazuki T, Shirasawa S, Hagan MP, Grant S, Dent P.
    Mol Cancer Ther; 2005 Feb; 4(2):243-55. PubMed ID: 15713896
    [Abstract] [Full Text] [Related]

  • 2. Activated forms of H-RAS and K-RAS differentially regulate membrane association of PI3K, PDK-1, and AKT and the effect of therapeutic kinase inhibitors on cell survival.
    Carón RW, Yacoub A, Li M, Zhu X, Mitchell C, Hong Y, Hawkins W, Sasazuki T, Shirasawa S, Kozikowski AP, Dennis PA, Hagan MP, Grant S, Dent P.
    Mol Cancer Ther; 2005 Feb; 4(2):257-70. PubMed ID: 15713897
    [Abstract] [Full Text] [Related]

  • 3. Radiation-stimulated ERK1/2 and JNK1/2 signaling can promote cell cycle progression in human colon cancer cells.
    Carón RW, Yacoub A, Mitchell C, Zhu X, Hong Y, Sasazuki T, Shirasawa S, Hagan MP, Grant S, Dent P.
    Cell Cycle; 2005 Mar; 4(3):456-64. PubMed ID: 15655348
    [Abstract] [Full Text] [Related]

  • 4. Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects.
    Jackson JG, St Clair P, Sliwkowski MX, Brattain MG.
    Cancer Res; 2004 Apr 01; 64(7):2601-9. PubMed ID: 15059917
    [Abstract] [Full Text] [Related]

  • 5. Autocrine heregulin generates growth factor independence and blocks apoptosis in colon cancer cells.
    Venkateswarlu S, Dawson DM, St Clair P, Gupta A, Willson JK, Brattain MG.
    Oncogene; 2002 Jan 03; 21(1):78-86. PubMed ID: 11791178
    [Abstract] [Full Text] [Related]

  • 6. Ras mediates radioresistance through both phosphatidylinositol 3-kinase-dependent and Raf-dependent but mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-independent signaling pathways.
    Grana TM, Rusyn EV, Zhou H, Sartor CI, Cox AD.
    Cancer Res; 2002 Jul 15; 62(14):4142-50. PubMed ID: 12124353
    [Abstract] [Full Text] [Related]

  • 7. Opposite effects of Ha-Ras and Ki-Ras on radiation-induced apoptosis via differential activation of PI3K/Akt and Rac/p38 mitogen-activated protein kinase signaling pathways.
    Choi JA, Park MT, Kang CM, Um HD, Bae S, Lee KH, Kim TH, Kim JH, Cho CK, Lee YS, Chung HY, Lee SJ.
    Oncogene; 2004 Jan 08; 23(1):9-20. PubMed ID: 14712206
    [Abstract] [Full Text] [Related]

  • 8. K-RAS(V12) induces autocrine production of EGFR ligands and mediates radioresistance through EGFR-dependent Akt signaling and activation of DNA-PKcs.
    Minjgee M, Toulany M, Kehlbach R, Giehl K, Rodemann HP.
    Int J Radiat Oncol Biol Phys; 2011 Dec 01; 81(5):1506-14. PubMed ID: 21985943
    [Abstract] [Full Text] [Related]

  • 9. Targeting epidermal growth factor receptor-associated signaling pathways in non-small cell lung cancer cells: implication in radiation response.
    Choi EJ, Ryu YK, Kim SY, Wu HG, Kim JS, Kim IH, Kim IA.
    Mol Cancer Res; 2010 Jul 01; 8(7):1027-36. PubMed ID: 20587532
    [Abstract] [Full Text] [Related]

  • 10. Selective inhibition of Ras, phosphoinositide 3 kinase, and Akt isoforms increases the radiosensitivity of human carcinoma cell lines.
    Kim IA, Bae SS, Fernandes A, Wu J, Muschel RJ, McKenna WG, Birnbaum MJ, Bernhard EJ.
    Cancer Res; 2005 Sep 01; 65(17):7902-10. PubMed ID: 16140961
    [Abstract] [Full Text] [Related]

  • 11. Heregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 co-receptor.
    Hellyer NJ, Kim MS, Koland JG.
    J Biol Chem; 2001 Nov 09; 276(45):42153-61. PubMed ID: 11546794
    [Abstract] [Full Text] [Related]

  • 12. Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.
    Thimmaiah KN, Easton J, Huang S, Veverka KA, Germain GS, Harwood FC, Houghton PJ.
    Cancer Res; 2003 Jan 15; 63(2):364-74. PubMed ID: 12543789
    [Abstract] [Full Text] [Related]

  • 13. Radiotherapy-induced signal transduction.
    Yacoub A, Miller A, Caron RW, Qiao L, Curiel DA, Fisher PB, Hagan MP, Grant S, Dent P.
    Endocr Relat Cancer; 2006 Dec 15; 13 Suppl 1():S99-114. PubMed ID: 17259563
    [Abstract] [Full Text] [Related]

  • 14. Ran is a potential therapeutic target for cancer cells with molecular changes associated with activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK pathways.
    Yuen HF, Chan KK, Grills C, Murray JT, Platt-Higgins A, Eldin OS, O'Byrne K, Janne P, Fennell DA, Johnston PG, Rudland PS, El-Tanani M.
    Clin Cancer Res; 2012 Jan 15; 18(2):380-91. PubMed ID: 22090358
    [Abstract] [Full Text] [Related]

  • 15. The epidermal growth factor receptor pathway mediates resistance to sequential administration of radiation and chemotherapy in primary human glioblastoma cells in a RAS-dependent manner.
    Chakravarti A, Chakladar A, Delaney MA, Latham DE, Loeffler JS.
    Cancer Res; 2002 Aug 01; 62(15):4307-15. PubMed ID: 12154034
    [Abstract] [Full Text] [Related]

  • 16. Activated Ki-Ras suppresses 12-O-tetradecanoylphorbol-13-acetate-induced activation of the c-Jun NH2-terminal kinase pathway in human colon cancer cells.
    Okumura K, Shirasawa S, Nishioka M, Sasazuki T.
    Cancer Res; 1999 May 15; 59(10):2445-50. PubMed ID: 10344756
    [Abstract] [Full Text] [Related]

  • 17. Stimulated PI3K-AKT signaling mediated through ligand or radiation-induced EGFR depends indirectly, but not directly, on constitutive K-Ras activity.
    Toulany M, Baumann M, Rodemann HP.
    Mol Cancer Res; 2007 Aug 15; 5(8):863-72. PubMed ID: 17699110
    [Abstract] [Full Text] [Related]

  • 18. Akt-mediated survival of oligodendrocytes induced by neuregulins.
    Flores AI, Mallon BS, Matsui T, Ogawa W, Rosenzweig A, Okamoto T, Macklin WB.
    J Neurosci; 2000 Oct 15; 20(20):7622-30. PubMed ID: 11027222
    [Abstract] [Full Text] [Related]

  • 19. Activation of the phosphatidylinositol 3-kinase/Akt pathway prevents radiation-induced apoptosis in breast cancer cells.
    Söderlund K, Pérez-Tenorio G, Stål O.
    Int J Oncol; 2005 Jan 15; 26(1):25-32. PubMed ID: 15586221
    [Abstract] [Full Text] [Related]

  • 20. Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways.
    Rusyn EV, Reynolds ER, Shao H, Grana TM, Chan TO, Andres DA, Cox AD.
    Oncogene; 2000 Sep 28; 19(41):4685-94. PubMed ID: 11032018
    [Abstract] [Full Text] [Related]

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