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Journal Abstract Search


598 related items for PubMed ID: 15717010

  • 1. Failures and successes of NMDA receptor antagonists: molecular basis for the use of open-channel blockers like memantine in the treatment of acute and chronic neurologic insults.
    Lipton SA.
    NeuroRx; 2004 Jan; 1(1):101-10. PubMed ID: 15717010
    [Abstract] [Full Text] [Related]

  • 2. Paradigm shift in NMDA receptor antagonist drug development: molecular mechanism of uncompetitive inhibition by memantine in the treatment of Alzheimer's disease and other neurologic disorders.
    Lipton SA.
    J Alzheimers Dis; 2004 Dec; 6(6 Suppl):S61-74. PubMed ID: 15665416
    [Abstract] [Full Text] [Related]

  • 3. The molecular basis of memantine action in Alzheimer's disease and other neurologic disorders: low-affinity, uncompetitive antagonism.
    Lipton SA.
    Curr Alzheimer Res; 2005 Apr; 2(2):155-65. PubMed ID: 15974913
    [Abstract] [Full Text] [Related]

  • 4. Pathologically-activated therapeutics for neuroprotection: mechanism of NMDA receptor block by memantine and S-nitrosylation.
    Lipton SA.
    Curr Drug Targets; 2007 May; 8(5):621-32. PubMed ID: 17504105
    [Abstract] [Full Text] [Related]

  • 5. Inflammatory mediators leading to protein misfolding and uncompetitive/fast off-rate drug therapy for neurodegenerative disorders.
    Lipton SA, Gu Z, Nakamura T.
    Int Rev Neurobiol; 2007 May; 82():1-27. PubMed ID: 17678953
    [Abstract] [Full Text] [Related]

  • 6. The chemical biology of clinically tolerated NMDA receptor antagonists.
    Chen HS, Lipton SA.
    J Neurochem; 2006 Jun; 97(6):1611-26. PubMed ID: 16805772
    [Abstract] [Full Text] [Related]

  • 7. Possible role for memantine in protecting retinal ganglion cells from glaucomatous damage.
    Lipton SA.
    Surv Ophthalmol; 2003 Apr; 48 Suppl 1():S38-46. PubMed ID: 12852433
    [Abstract] [Full Text] [Related]

  • 8. Paradigm shift in neuroprotection by NMDA receptor blockade: memantine and beyond.
    Lipton SA.
    Nat Rev Drug Discov; 2006 Feb; 5(2):160-70. PubMed ID: 16424917
    [Abstract] [Full Text] [Related]

  • 9. Targeting excitotoxic/free radical signaling pathways for therapeutic intervention in glaucoma.
    Seki M, Lipton SA.
    Prog Brain Res; 2008 Feb; 173():495-510. PubMed ID: 18929130
    [Abstract] [Full Text] [Related]

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  • 11. Dementia of Alzheimer's disease and other neurodegenerative disorders--memantine, a new hope.
    Sonkusare SK, Kaul CL, Ramarao P.
    Pharmacol Res; 2005 Jan; 51(1):1-17. PubMed ID: 15519530
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  • 14. Alzheimer's disease and the glutamate NMDA receptor.
    Doraiswamy PM.
    Psychopharmacol Bull; 2003 Jan; 37(2):41-9. PubMed ID: 14566213
    [Abstract] [Full Text] [Related]

  • 15. Management of moderate to severe Alzheimer's disease: focus on memantine.
    Dominguez E, Chin TY, Chen CP, Wu TY.
    Taiwan J Obstet Gynecol; 2011 Dec; 50(4):415-23. PubMed ID: 22212311
    [Abstract] [Full Text] [Related]

  • 16. N-methyl-D-aspartate receptor channel blockers prevent pentylenetetrazole-induced convulsions and morphological changes in rat brain neurons.
    Zaitsev AV, Kim KKh, Vasilev DS, Lukomskaya NY, Lavrentyeva VV, Tumanova NL, Zhuravin IA, Magazanik LG.
    J Neurosci Res; 2015 Mar; 93(3):454-65. PubMed ID: 25359451
    [Abstract] [Full Text] [Related]

  • 17. Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity.
    Chen HS, Pellegrini JW, Aggarwal SK, Lei SZ, Warach S, Jensen FE, Lipton SA.
    J Neurosci; 1992 Nov; 12(11):4427-36. PubMed ID: 1432103
    [Abstract] [Full Text] [Related]

  • 18. [Glutamate-related excitotoxicity neuroprotection with memantine, an uncompetitive antagonist of NMDA-glutamate receptor, in Alzheimer's disease and vascular dementia].
    Tanović A, Alfaro V.
    Rev Neurol; 1992 Nov; 42(10):607-16. PubMed ID: 16703529
    [Abstract] [Full Text] [Related]

  • 19. Neuroprotection against excitotoxicity by N-alkylglycines in rat hippocampal neurons.
    Valera E, Fernández-Salguero PM, Planells-Cases R, Messeguer A, Van Den Nest W, Carreño C, Ferrer-Montiel A, Merino JM.
    Neuromolecular Med; 2002 Nov; 2(3):271-80. PubMed ID: 12622405
    [Abstract] [Full Text] [Related]

  • 20. [The clinical relevance of memantine use].
    Sobów T.
    Psychiatr Pol; 2004 Nov; 38(2):321-30. PubMed ID: 15307296
    [Abstract] [Full Text] [Related]


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