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920 related items for PubMed ID: 15727878

  • 1. 1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), alpha1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics.
    Bojarski AJ, Paluchowska MH, Duszyńska B, Kłodzińska A, Tatarczyńska E, Chojnacka-Wójcik E.
    Bioorg Med Chem; 2005 Mar 15; 13(6):2293-303. PubMed ID: 15727878
    [Abstract] [Full Text] [Related]

  • 2. New 5-hydroxytryptamine(1A) receptor ligands containing a norbornene nucleus: synthesis and in vitro pharmacological evaluation.
    Fiorino F, Perissutti E, Severino B, Santagada V, Cirillo D, Terracciano S, Massarelli P, Bruni G, Collavoli E, Renner C, Caliendo G.
    J Med Chem; 2005 Aug 25; 48(17):5495-503. PubMed ID: 16107148
    [Abstract] [Full Text] [Related]

  • 3. Structure-intrinsic activity relationship studies in the group of 1-imido/amido substituted 4-(4-arylpiperazin-1-yl)cyclohexane derivatives; new, potent 5-HT1A receptor agents with anxiolytic- like activity.
    Bojarski AJ, Paluchowska MH, Duszyńska B, Bugno R, Kłodzińska A, Tatarczyńska E, Chojnacka-Wójcik E.
    Bioorg Med Chem; 2006 Mar 01; 14(5):1391-402. PubMed ID: 16266808
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and structure-activity relationships of a new model of arylpiperazines. 4. 1-[omega-(4-Arylpiperazin-1-yl)alkyl]-3-(diphenylmethylene) - 2, 5-pyrrolidinediones and -3-(9H-fluoren-9-ylidene)-2, 5-pyrrolidinediones: study of the steric requirements of the terminal amide fragment on 5-HT1A affinity/selectivity.
    López-Rodríguez ML, Morcillo MJ, Rovat TK, Fernández E, Vicente B, Sanz AM, Hernández M, Orensanz L.
    J Med Chem; 1999 Jan 14; 42(1):36-49. PubMed ID: 9888831
    [Abstract] [Full Text] [Related]

  • 5. The influence of modifications in imide fragment structure on 5-HT(1A) and 5-HT(7) receptor affinity and in vivo pharmacological properties of some new 1-(m-trifluoromethylphenyl)piperazines.
    Paluchowska MH, Bugno R, Duszyńska B, Tatarczyńska E, Nikiforuk A, Lenda T, Chojnacka-Wójcik E.
    Bioorg Med Chem; 2007 Nov 15; 15(22):7116-25. PubMed ID: 17825569
    [Abstract] [Full Text] [Related]

  • 6. New 4-[omega-(diarylmethylamino)alkyl]- and 4-[omega-(diarylmethoxy)alkyl]-1-arylpiperazines as selective 5-HT1A/5-HT2A receptor ligands with differentiated in vivo activity.
    Paluchowska MH, Charakchieva-Minol S, Tatarczyńska E, Kłodzińska A, Stachowicz K, Chojnacka-Wójcik E.
    Pol J Pharmacol; 2004 Nov 15; 56(6):743-54. PubMed ID: 15662087
    [Abstract] [Full Text] [Related]

  • 7. Novel 4-alkyl-1-arylpiperazines and 1,2,3,4-tetrahydroisoquinolines containing diphenylmethylamino or diphenylmethoxy fragment with differentiated 5-HT1A/5-HT2A/D2 receptor activity.
    Paluchowska MH, Mokrosz MJ, Charakchieva-Minol S, Duszyńska B, Kozioł A, Wesołowska A, Stachowicz K, Chojnacka-Wójcik E.
    Pol J Pharmacol; 2003 Nov 15; 55(4):543-52. PubMed ID: 14581712
    [Abstract] [Full Text] [Related]

  • 8. Novel class of arylpiperazines containing N-acylated amino acids: their synthesis, 5-HT1A, 5-HT2A receptor affinity, and in vivo pharmacological evaluation.
    Zajdel P, Subra G, Bojarski AJ, Duszyńska B, Tatarczyńska E, Nikiforuk A, Chojnacka-Wójcik E, Pawłowski M, Martinez J.
    Bioorg Med Chem; 2007 Apr 15; 15(8):2907-19. PubMed ID: 17321139
    [Abstract] [Full Text] [Related]

  • 9. Synthesis, 5-HT1A and 5-HT2A receptor activity of new 1-phenylpiperazinylpropyl derivatives with arylalkyl substituents in position 7 of purine-2,6-dione.
    Chloń G, Pawłowski M, Duszyńska B, Szaro A, Tatarczńska E, Kłodzińska AL, Chojnacka-Wójcik E.
    Pol J Pharmacol; 2001 Apr 15; 53(4):359-68. PubMed ID: 11990082
    [Abstract] [Full Text] [Related]

  • 10. New arylpiperazine 5-HT(1A) receptor ligands containing the pyrimido[2,1-f]purine fragment: synthesis, in vitro, and in vivo pharmacological evaluation.
    Jurczyk S, Kołaczkowski M, Maryniak E, Zajdel P, Pawłowski M, Tatarczyńska E, Kłodzińska A, Chojnacka-Wójcik E, Bojarski AJ, Charakchieva-Minol S, Duszyńska B, Nowak G, Maciag D.
    J Med Chem; 2004 May 06; 47(10):2659-66. PubMed ID: 15115407
    [Abstract] [Full Text] [Related]

  • 11. 2-H- and 2-acyl-9- [omega-[4-(2-methoxyphenyl)piperazinyl]-alkyl]-1,2,3,4-tetrahydro-beta-carbolines as ligands of 5-HT1A and 5-HT2A receptors.
    Boksa J, Mokrosz MJ, Charakchieva-Minol S, Tatarczyńska E, Kłodzińska A, Wesołowska A, Misztal S.
    Pol J Pharmacol; 2001 May 06; 53(5):501-8. PubMed ID: 11990069
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and structure-activity relationships of a new model of arylpiperazines. 8. Computational simulation of ligand-receptor interaction of 5-HT(1A)R agonists with selectivity over alpha1-adrenoceptors.
    López-Rodríguez ML, Morcillo MJ, Fernández E, Benhamú B, Tejada I, Ayala D, Viso A, Campillo M, Pardo L, Delgado M, Manzanares J, Fuentes JA.
    J Med Chem; 2005 Apr 07; 48(7):2548-58. PubMed ID: 15801844
    [Abstract] [Full Text] [Related]

  • 13. Pharmacological analysis of the hypothermic effects of NAN-190 and its analogs, postsynaptic 5-HT1A receptor antagonists, in mice.
    Wesołowska A, Borycz J, Paluchowska MH, Chojnacka-Wójcik E.
    Pol J Pharmacol; 2002 Apr 07; 54(4):391-9. PubMed ID: 12523493
    [Abstract] [Full Text] [Related]

  • 14. 1,4-Benzoxazin-3(4H)-one derivatives and related compounds as 5-HT1A and 5-HT2A receptor ligands; the effect of the terminal amide fragment on the 5-HT1A/5-HT2A affinity and functional activity.
    Mokrosz MJ, Kowalski P, Kowalska T, Majka Z, Duszyńska B, Charakchieva-Minol S, Szaro A, Tatarczyńska E, Kłodzińska A, Chojnacka-Wójcik E.
    Pol J Pharmacol; 1998 Apr 07; 50(4-5):333-40. PubMed ID: 10091718
    [Abstract] [Full Text] [Related]

  • 15. trans-4-[4-(Methoxyphenyl)cyclohexyl]-1-arylpiperazines: a new class of potent and selective 5-HT(1A) receptor ligands as conformationally constrained analogues of 4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]-1-arylpiperazines.
    Perrone R, Berardi F, Colabufo NA, Leopoldo M, Lacivita E, Tortorella V, Leonardi A, Poggesi E, Testa R.
    J Med Chem; 2001 Dec 06; 44(25):4431-42. PubMed ID: 11728188
    [Abstract] [Full Text] [Related]

  • 16. Synthesis, anticonvulsant activity and 5-HT1A, 5-HT2A receptor affinity of new N-[(4-arylpiperazin-1-yl)-alkyl] derivatives of 2-azaspiro[4.4]nonane and [4.5]decane-1,3-dione.
    Obniska J, Kołaczkowski M, Bojarski AJ, Duszyńska B.
    Eur J Med Chem; 2006 Jul 06; 41(7):874-81. PubMed ID: 16600439
    [Abstract] [Full Text] [Related]

  • 17. 1-cinnamyl-4-(2-methoxyphenyl)piperazines: synthesis, binding properties, and docking to dopamine (D(2)) and serotonin (5-HT(1A)) receptors.
    Penjisević J, Sukalović V, Andrić D, Kostić-Rajacić S, Soskić V, Roglić G.
    Arch Pharm (Weinheim); 2007 Sep 06; 340(9):456-65. PubMed ID: 17763374
    [Abstract] [Full Text] [Related]

  • 18. 1-aryl-4-[(5-methoxy-1,2,3, 4-tetrahydronaphthalen-1-yl)alkyl]piperazines and their analogues: influence of the stereochemistry of the tetrahydronaphthalen-1-yl nucleus on 5-HT1A receptor affinity and selectivity versus alpha1 and D2 receptors. 5.
    Perrone R, Berardi F, Colabufo NA, Leopoldo M, Tortorella V.
    J Med Chem; 1999 Feb 11; 42(3):490-6. PubMed ID: 9986719
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and structure-activity relationships of a new model of arylpiperazines. 1. 2-[[4-(o-methoxyphenyl)piperazin-1-yl]methyl]-1, 3-dioxoperhydroimidazo[1,5-alpha]pyridine: a selective 5-HT1A receptor agonist.
    López-Rodríguez ML, Rosado ML, Benhamú B, Morcillo MJ, Sanz AM, Orensanz L, Beneitez ME, Fuentes JA, Manzanares J.
    J Med Chem; 1996 Oct 25; 39(22):4439-50. PubMed ID: 8893838
    [Abstract] [Full Text] [Related]

  • 20. 7-Arylpiperazinylalkyl and 7-tetrahydroisoquinolinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and some of their purine-2,6,8-trione analogs as 5-HT(1A), 5-HT(2A), and 5-HT(7) serotonin receptor ligands.
    Chłoń-Rzepa G, Zmudzki P, Zajdel P, Bojarski AJ, Duszyńska B, Nikiforuk A, Tatarczyńska E, Pawłowski M.
    Bioorg Med Chem; 2007 Aug 01; 15(15):5239-50. PubMed ID: 17517514
    [Abstract] [Full Text] [Related]

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