These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

185 related items for PubMed ID: 15743173

  • 1. Development and preliminary optimization of indole-N-acetamide inhibitors of hepatitis C virus NS5B polymerase.
    Harper S, Pacini B, Avolio S, Di Filippo M, Migliaccio G, Laufer R, De Francesco R, Rowley M, Narjes F.
    J Med Chem; 2005 Mar 10; 48(5):1314-7. PubMed ID: 15743173
    [Abstract] [Full Text] [Related]

  • 2. Potent inhibitors of subgenomic hepatitis C virus RNA replication through optimization of indole-N-acetamide allosteric inhibitors of the viral NS5B polymerase.
    Harper S, Avolio S, Pacini B, Di Filippo M, Altamura S, Tomei L, Paonessa G, Di Marco S, Carfi A, Giuliano C, Padron J, Bonelli F, Migliaccio G, De Francesco R, Laufer R, Rowley M, Narjes F.
    J Med Chem; 2005 Jul 14; 48(14):4547-57. PubMed ID: 15999993
    [Abstract] [Full Text] [Related]

  • 3. The discovery of pyrano[3,4-b]indole-based allosteric inhibitors of HCV NS5B polymerase with in vivo activity.
    Laporte MG, Jackson RW, Draper TL, Gaboury JA, Galie K, Herbertz T, Hussey AR, Rippin SR, Benetatos CA, Chunduru SK, Christensen JS, Coburn GA, Rizzo CJ, Rhodes G, O'Connell J, Howe AY, Mansour TS, Collett MS, Pevear DC, Young DC, Gao T, Tyrrell DL, Kneteman NM, Burns CJ, Condon SM.
    ChemMedChem; 2008 Oct 14; 3(10):1508-15. PubMed ID: 18729128
    [No Abstract] [Full Text] [Related]

  • 4. Improved replicon cellular activity of non-nucleoside allosteric inhibitors of HCV NS5B polymerase: from benzimidazole to indole scaffolds.
    Beaulieu PL, Gillard J, Bykowski D, Brochu C, Dansereau N, Duceppe JS, Haché B, Jakalian A, Lagacé L, LaPlante S, McKercher G, Moreau E, Perreault S, Stammers T, Thauvette L, Warrington J, Kukolj G.
    Bioorg Med Chem Lett; 2006 Oct 01; 16(19):4987-93. PubMed ID: 16908138
    [Abstract] [Full Text] [Related]

  • 5.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 6. Discovery of (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid (MK-3281), a potent and orally bioavailable finger-loop inhibitor of the hepatitis C virus NS5B polymerase.
    Narjes F, Crescenzi B, Ferrara M, Habermann J, Colarusso S, Ferreira Mdel R, Stansfield I, Mackay AC, Conte I, Ercolani C, Zaramella S, Palumbi MC, Meuleman P, Leroux-Roels G, Giuliano C, Fiore F, Di Marco S, Baiocco P, Koch U, Migliaccio G, Altamura S, Laufer R, De Francesco R, Rowley M.
    J Med Chem; 2011 Jan 13; 54(1):289-301. PubMed ID: 21141896
    [Abstract] [Full Text] [Related]

  • 7. Chemical genetics-based discovery of indole derivatives as HCV NS5B polymerase inhibitors.
    Jin G, Lee S, Choi M, Son S, Kim GW, Oh JW, Lee C, Lee K.
    Eur J Med Chem; 2014 Mar 21; 75():413-25. PubMed ID: 24561671
    [Abstract] [Full Text] [Related]

  • 8. Development of carboxylic acid replacements in indole-N-acetamide inhibitors of hepatitis C virus NS5B polymerase.
    Stansfield I, Pompei M, Conte I, Ercolani C, Migliaccio G, Jairaj M, Giuliano C, Rowley M, Narjes F.
    Bioorg Med Chem Lett; 2007 Sep 15; 17(18):5143-9. PubMed ID: 17681757
    [Abstract] [Full Text] [Related]

  • 9. Preclinical characterization of BMS-791325, an allosteric inhibitor of hepatitis C Virus NS5B polymerase.
    Lemm JA, Liu M, Gentles RG, Ding M, Voss S, Pelosi LA, Wang YK, Rigat KL, Mosure KW, Bender JA, Knipe JO, Colonno R, Meanwell NA, Kadow JF, Santone KS, Roberts SB, Gao M.
    Antimicrob Agents Chemother; 2014 Jun 15; 58(6):3485-95. PubMed ID: 24733465
    [Abstract] [Full Text] [Related]

  • 10. Synthesis of new 4,5-dihydrofuranoindoles and their evaluation as HCV NS5B polymerase inhibitors.
    Velázquez F, Venkatraman S, Lesburg CA, Duca J, Rosenblum SB, Kozlowski JA, Njoroge FG.
    Org Lett; 2012 Jan 20; 14(2):556-9. PubMed ID: 22220815
    [Abstract] [Full Text] [Related]

  • 11.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 12.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 13. The novel nucleoside analog R1479 (4'-azidocytidine) is a potent inhibitor of NS5B-dependent RNA synthesis and hepatitis C virus replication in cell culture.
    Klumpp K, Lévêque V, Le Pogam S, Ma H, Jiang WR, Kang H, Granycome C, Singer M, Laxton C, Hang JQ, Sarma K, Smith DB, Heindl D, Hobbs CJ, Merrett JH, Symons J, Cammack N, Martin JA, Devos R, Nájera I.
    J Biol Chem; 2006 Feb 17; 281(7):3793-9. PubMed ID: 16316989
    [Abstract] [Full Text] [Related]

  • 14. Characterization of aurintricarboxylic acid as a potent hepatitis C virus replicase inhibitor.
    Chen Y, Bopda-Waffo A, Basu A, Krishnan R, Silberstein E, Taylor DR, Talele TT, Arora P, Kaushik-Basu N.
    Antivir Chem Chemother; 2009 Sep 25; 20(1):19-36. PubMed ID: 19794229
    [Abstract] [Full Text] [Related]

  • 15. Allosteric inhibition of the hepatitis C virus NS5B RNA dependent RNA polymerase.
    Koch U, Narjes F.
    Infect Disord Drug Targets; 2006 Mar 25; 6(1):31-41. PubMed ID: 16787302
    [Abstract] [Full Text] [Related]

  • 16. Non-nucleoside benzimidazole-based allosteric inhibitors of the hepatitis C virus NS5B polymerase: inhibition of subgenomic hepatitis C virus RNA replicons in Huh-7 cells.
    Beaulieu PL, Bousquet Y, Gauthier J, Gillard J, Marquis M, McKercher G, Pellerin C, Valois S, Kukolj G.
    J Med Chem; 2004 Dec 30; 47(27):6884-92. PubMed ID: 15615537
    [Abstract] [Full Text] [Related]

  • 17. Recent advances in discovery and development of promising therapeutics against hepatitis C virus NS5B RNA-dependent RNA polymerase.
    Wu JZ, Yao N, Walker M, Hong Z.
    Mini Rev Med Chem; 2005 Dec 30; 5(12):1103-12. PubMed ID: 16375756
    [Abstract] [Full Text] [Related]

  • 18. Non-nucleoside inhibitors of the hepatitis C virus NS5B RNA-dependant RNA polymerase: 2-aryl-3-heteroaryl-1,3-thiazolidin-4-one derivatives.
    Rawal RK, Katti SB, Kaushik-Basu N, Arora P, Pan Z.
    Bioorg Med Chem Lett; 2008 Dec 01; 18(23):6110-4. PubMed ID: 18947995
    [Abstract] [Full Text] [Related]

  • 19.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 20. Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides.
    Chan L, Das SK, Reddy TJ, Poisson C, Proulx M, Pereira O, Courchesne M, Roy C, Wang W, Siddiqui A, Yannopoulos CG, Nguyen-Ba N, Labrecque D, Bethell R, Hamel M, Courtemanche-Asselin P, L'Heureux L, David M, Nicolas O, Brunette S, Bilimoria D, Bédard J.
    Bioorg Med Chem Lett; 2004 Feb 09; 14(3):793-6. PubMed ID: 14741291
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 10.