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388 related items for PubMed ID: 15753652

  • 1. Mitotic spindle checkpoint inactivation by trichostatin a defines a mechanism for increasing cancer cell killing by microtubule-disrupting agents.
    Dowling M, Voong KR, Kim M, Keutmann MK, Harris E, Kao GD.
    Cancer Biol Ther; 2005 Feb; 4(2):197-206. PubMed ID: 15753652
    [Abstract] [Full Text] [Related]

  • 2. Kinetochore localisation and phosphorylation of the mitotic checkpoint components Bub1 and BubR1 are differentially regulated by spindle events in human cells.
    Taylor SS, Hussein D, Wang Y, Elderkin S, Morrow CJ.
    J Cell Sci; 2001 Dec; 114(Pt 24):4385-95. PubMed ID: 11792804
    [Abstract] [Full Text] [Related]

  • 3. Caspase-mediated specific cleavage of BubR1 is a determinant of mitotic progression.
    Kim M, Murphy K, Liu F, Parker SE, Dowling ML, Baff W, Kao GD.
    Mol Cell Biol; 2005 Nov; 25(21):9232-48. PubMed ID: 16227576
    [Abstract] [Full Text] [Related]

  • 4. Inactivation of the mitotic checkpoint as a determinant of the efficacy of microtubule-targeted drugs in killing human cancer cells.
    Lee EA, Keutmann MK, Dowling ML, Harris E, Chan G, Kao GD.
    Mol Cancer Ther; 2004 Jun; 3(6):661-9. PubMed ID: 15210851
    [Abstract] [Full Text] [Related]

  • 5. Different spindle checkpoint proteins monitor microtubule attachment and tension at kinetochores in Drosophila cells.
    Logarinho E, Bousbaa H, Dias JM, Lopes C, Amorim I, Antunes-Martins A, Sunkel CE.
    J Cell Sci; 2004 Apr 01; 117(Pt 9):1757-71. PubMed ID: 15075237
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  • 8. Inhibition of histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation.
    Shin HJ, Baek KH, Jeon AH, Kim SJ, Jang KL, Sung YC, Kim CM, Lee CW.
    Oncogene; 2003 Jun 19; 22(25):3853-8. PubMed ID: 12813458
    [Abstract] [Full Text] [Related]

  • 9. Survivin is required for stable checkpoint activation in taxol-treated HeLa cells.
    Carvalho A, Carmena M, Sambade C, Earnshaw WC, Wheatley SP.
    J Cell Sci; 2003 Jul 15; 116(Pt 14):2987-98. PubMed ID: 12783991
    [Abstract] [Full Text] [Related]

  • 10. The ability to survive mitosis in the presence of microtubule poisons differs significantly between human nontransformed (RPE-1) and cancer (U2OS, HeLa) cells.
    Brito DA, Rieder CL.
    Cell Motil Cytoskeleton; 2009 Aug 15; 66(8):437-47. PubMed ID: 18792104
    [Abstract] [Full Text] [Related]

  • 11. An HDAC inhibitor, trichostatin A, induces a delay at G2/M transition, slippage of spindle checkpoint, and cell death in a transcription-dependent manner.
    Noh EJ, Lim DS, Jeong G, Lee JS.
    Biochem Biophys Res Commun; 2009 Jan 16; 378(3):326-31. PubMed ID: 19038231
    [Abstract] [Full Text] [Related]

  • 12. The spindle assembly checkpoint is satisfied in the absence of interkinetochore tension during mitosis with unreplicated genomes.
    O'Connell CB, Loncarek J, Hergert P, Kourtidis A, Conklin DS, Khodjakov A.
    J Cell Biol; 2008 Oct 06; 183(1):29-36. PubMed ID: 18824563
    [Abstract] [Full Text] [Related]

  • 13. BubR1 deficiency results in enhanced activation of MEK and ERKs upon microtubule stresses.
    Yang YL, Duan Q, Guo TB, Wang XX, Ruan Q, Xu GT, Zhang JW, Lu ZY, Xu M, Lu L, Dai W.
    Cell Prolif; 2007 Jun 06; 40(3):397-410. PubMed ID: 17531083
    [Abstract] [Full Text] [Related]

  • 14. p55CDC/hCDC20 mutant induces mitotic catastrophe by inhibiting the MAD2-dependent spindle checkpoint activity in tumor cells.
    Sihn CR, Suh EJ, Lee KH, Kim TY, Kim SH.
    Cancer Lett; 2003 Nov 25; 201(2):203-10. PubMed ID: 14607335
    [Abstract] [Full Text] [Related]

  • 15. The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint.
    Hauf S, Cole RW, LaTerra S, Zimmer C, Schnapp G, Walter R, Heckel A, van Meel J, Rieder CL, Peters JM.
    J Cell Biol; 2003 Apr 28; 161(2):281-94. PubMed ID: 12707311
    [Abstract] [Full Text] [Related]

  • 16. Chk1 is required for spindle checkpoint function.
    Zachos G, Black EJ, Walker M, Scott MT, Vagnarelli P, Earnshaw WC, Gillespie DA.
    Dev Cell; 2007 Feb 28; 12(2):247-60. PubMed ID: 17276342
    [Abstract] [Full Text] [Related]

  • 17. TRAIL inactivates the mitotic checkpoint and potentiates death induced by microtubule-targeting agents in human cancer cells.
    Kim M, Liao J, Dowling ML, Voong KR, Parker SE, Wang S, El-Deiry WS, Kao GD.
    Cancer Res; 2008 May 01; 68(9):3440-9. PubMed ID: 18451172
    [Abstract] [Full Text] [Related]

  • 18. AuroraA overexpression overrides the mitotic spindle checkpoint triggered by nocodazole, a microtubule destabilizer.
    Jiang Y, Zhang Y, Lees E, Seghezzi W.
    Oncogene; 2003 Nov 13; 22(51):8293-301. PubMed ID: 14614453
    [Abstract] [Full Text] [Related]

  • 19. hNuf2 inhibition blocks stable kinetochore-microtubule attachment and induces mitotic cell death in HeLa cells.
    DeLuca JG, Moree B, Hickey JM, Kilmartin JV, Salmon ED.
    J Cell Biol; 2002 Nov 25; 159(4):549-55. PubMed ID: 12438418
    [Abstract] [Full Text] [Related]

  • 20. Inhibitors of histone deacetylases alter kinetochore assembly by disrupting pericentromeric heterochromatin.
    Robbins AR, Jablonski SA, Yen TJ, Yoda K, Robey R, Bates SE, Sackett DL.
    Cell Cycle; 2005 May 25; 4(5):717-26. PubMed ID: 15846093
    [Abstract] [Full Text] [Related]

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