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509 related items for PubMed ID: 15753661

  • 1. Mcl-1 regulates survival and sensitivity to diverse apoptotic stimuli in human non-small cell lung cancer cells.
    Song L, Coppola D, Livingston S, Cress D, Haura EB.
    Cancer Biol Ther; 2005 Mar; 4(3):267-76. PubMed ID: 15753661
    [Abstract] [Full Text] [Related]

  • 2. A small molecule pan-Bcl-2 family inhibitor, GX15-070, induces apoptosis and enhances cisplatin-induced apoptosis in non-small cell lung cancer cells.
    Li J, Viallet J, Haura EB.
    Cancer Chemother Pharmacol; 2008 Mar; 61(3):525-34. PubMed ID: 17505826
    [Abstract] [Full Text] [Related]

  • 3. Targeting BCL-2 family proteins to overcome drug resistance in non-small cell lung cancer.
    Wesarg E, Hoffarth S, Wiewrodt R, Kröll M, Biesterfeld S, Huber C, Schuler M.
    Int J Cancer; 2007 Dec 01; 121(11):2387-94. PubMed ID: 17688235
    [Abstract] [Full Text] [Related]

  • 4. AT-101 enhances gefitinib sensitivity in non-small cell lung cancer with EGFR T790M mutations.
    Zhao R, Zhou S, Xia B, Zhang CY, Hai P, Zhe H, Wang YY.
    BMC Cancer; 2016 Jul 18; 16():491. PubMed ID: 27431492
    [Abstract] [Full Text] [Related]

  • 5. DYRK1A suppression restrains Mcl-1 expression and sensitizes NSCLC cells to Bcl-2 inhibitors.
    Li Y, Zhou D, Xu S, Rao M, Zhang Z, Wu L, Zhang C, Lin N.
    Cancer Biol Med; 2020 May 15; 17(2):387-400. PubMed ID: 32587776
    [Abstract] [Full Text] [Related]

  • 6. EGFR mutations and AKT phosphorylation are markers for sensitivity to combined MCL-1 and BCL-2/xL inhibition in non-small cell lung cancer.
    Rice SJ, Liu X, Wang HG, Belani CP.
    PLoS One; 2019 May 15; 14(5):e0217657. PubMed ID: 31150457
    [Abstract] [Full Text] [Related]

  • 7. Bcl-x(L) and Myeloid cell leukaemia-1 contribute to apoptosis resistance of colorectal cancer cells.
    Schulze-Bergkamen H, Ehrenberg R, Hickmann L, Vick B, Urbanik T, Schimanski CC, Berger MR, Schad A, Weber A, Heeger S, Galle PR, Moehler M.
    World J Gastroenterol; 2008 Jun 28; 14(24):3829-40. PubMed ID: 18609706
    [Abstract] [Full Text] [Related]

  • 8. EGFR signaling defines Mcl⁻1 survival dependency in neuroblastoma.
    Nalluri S, Peirce SK, Tanos R, Abdella HA, Karmali D, Hogarty MD, Goldsmith KC.
    Cancer Biol Ther; 2015 Jun 28; 16(2):276-86. PubMed ID: 25756510
    [Abstract] [Full Text] [Related]

  • 9. Knockdown of the Bcl-2 gene increases sensitivity to EGFR tyrosine kinase inhibitors in the H1975 lung cancer cell line harboring T790M mutation.
    Zou M, Xia S, Zhuang L, Han N, Chu Q, Chao T, Peng P, Chen Y, Gui Q, Yu S.
    Int J Oncol; 2013 Jun 28; 42(6):2094-102. PubMed ID: 23588221
    [Abstract] [Full Text] [Related]

  • 10. 'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737.
    Lin X, Morgan-Lappe S, Huang X, Li L, Zakula DM, Vernetti LA, Fesik SW, Shen Y.
    Oncogene; 2007 Jun 07; 26(27):3972-9. PubMed ID: 17173063
    [Abstract] [Full Text] [Related]

  • 11. c-Myc dependent expression of pro-apoptotic Bim renders HER2-overexpressing breast cancer cells dependent on anti-apoptotic Mcl-1.
    Campone M, Noël B, Couriaud C, Grau M, Guillemin Y, Gautier F, Gouraud W, Charbonnel C, Campion L, Jézéquel P, Braun F, Barré B, Coqueret O, Barillé-Nion S, Juin P.
    Mol Cancer; 2011 Sep 07; 10():110. PubMed ID: 21899728
    [Abstract] [Full Text] [Related]

  • 12. A novel antisense oligonucleotide inhibiting several antiapoptotic Bcl-2 family members induces apoptosis and enhances chemosensitivity in androgen-independent human prostate cancer PC3 cells.
    Yamanaka K, Rocchi P, Miyake H, Fazli L, Vessella B, Zangemeister-Wittke U, Gleave ME.
    Mol Cancer Ther; 2005 Nov 07; 4(11):1689-98. PubMed ID: 16275990
    [Abstract] [Full Text] [Related]

  • 13. Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-x(L) is an essential survival protein of human myeloma cells.
    Derenne S, Monia B, Dean NM, Taylor JK, Rapp MJ, Harousseau JL, Bataille R, Amiot M.
    Blood; 2002 Jul 01; 100(1):194-9. PubMed ID: 12070027
    [Abstract] [Full Text] [Related]

  • 14. Antisense-mediated downregulation of anti-apoptotic proteins induces apoptosis and sensitizes head and neck squamous cell carcinoma cells to chemotherapy.
    Sharma H, Sen S, Lo Muzio L, Mariggiò A, Singh N.
    Cancer Biol Ther; 2005 Jul 01; 4(7):720-7. PubMed ID: 15917659
    [Abstract] [Full Text] [Related]

  • 15. RAGE potentiates EGFR signaling and interferes with the anticancer effect of gefitinib on NSCLC cells.
    Liao WL, Lin H, Li YH, Yang TY, Chen MC.
    Am J Physiol Cell Physiol; 2023 Nov 01; 325(5):C1313-C1325. PubMed ID: 37746694
    [Abstract] [Full Text] [Related]

  • 16. p53 enhances gefitinib-induced growth inhibition and apoptosis by regulation of Fas in non-small cell lung cancer.
    Rho JK, Choi YJ, Ryoo BY, Na II, Yang SH, Kim CH, Lee JC.
    Cancer Res; 2007 Feb 01; 67(3):1163-9. PubMed ID: 17283151
    [Abstract] [Full Text] [Related]

  • 17. Cyclic GMP/protein kinase G type-Iα (PKG-Iα) signaling pathway promotes CREB phosphorylation and maintains higher c-IAP1, livin, survivin, and Mcl-1 expression and the inhibition of PKG-Iα kinase activity synergizes with cisplatin in non-small cell lung cancer cells.
    Wong JC, Bathina M, Fiscus RR.
    J Cell Biochem; 2012 Nov 01; 113(11):3587-98. PubMed ID: 22740515
    [Abstract] [Full Text] [Related]

  • 18. BIM induction of apoptosis triggered by EGFR-sensitive and resistance cell lines of non-small-cell lung cancer.
    Li Z, Zhou S, Zhang L, Su C, Hang J, Zhao Y, Su B, Zhou C.
    Med Oncol; 2011 Jun 01; 28(2):572-7. PubMed ID: 20237869
    [Abstract] [Full Text] [Related]

  • 19. Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells.
    Taniai M, Grambihler A, Higuchi H, Werneburg N, Bronk SF, Farrugia DJ, Kaufmann SH, Gores GJ.
    Cancer Res; 2004 May 15; 64(10):3517-24. PubMed ID: 15150106
    [Abstract] [Full Text] [Related]

  • 20. Degradation of Mcl-1 through GSK-3β Activation Regulates Apoptosis Induced by Bufalin in Non-Small Cell Lung Cancer H1975 Cells.
    Kang XH, Zhang JH, Zhang QQ, Cui YH, Wang Y, Kou WZ, Miao ZH, Lu P, Wang LF, Xu ZY, Cao F.
    Cell Physiol Biochem; 2017 May 15; 41(5):2067-2076. PubMed ID: 28419994
    [Abstract] [Full Text] [Related]

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