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308 related items for PubMed ID: 15769904

  • 1. Gene expression profiling demonstrates that TGF-beta1 signals exclusively through receptor complexes involving Alk5 and identifies targets of TGF-beta signaling.
    Karlsson G, Liu Y, Larsson J, Goumans MJ, Lee JS, Thorgeirsson SS, Ringnér M, Karlsson S.
    Physiol Genomics; 2005 May 11; 21(3):396-403. PubMed ID: 15769904
    [Abstract] [Full Text] [Related]

  • 2. Dissecting the role of TGF-beta type I receptor/ALK5 in pancreatic ductal adenocarcinoma: Smad activation is crucial for both the tumor suppressive and prometastatic function.
    Schniewind B, Groth S, Sebens Müerköster S, Sipos B, Schäfer H, Kalthoff H, Fändrich F, Ungefroren H.
    Oncogene; 2007 Jul 19; 26(33):4850-62. PubMed ID: 17297450
    [Abstract] [Full Text] [Related]

  • 3. ALK1 opposes ALK5/Smad3 signaling and expression of extracellular matrix components in human chondrocytes.
    Finnson KW, Parker WL, ten Dijke P, Thorikay M, Philip A.
    J Bone Miner Res; 2008 Jun 19; 23(6):896-906. PubMed ID: 18333754
    [Abstract] [Full Text] [Related]

  • 4. Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-beta in human umbilical vein endothelial cells.
    Ota T, Fujii M, Sugizaki T, Ishii M, Miyazawa K, Aburatani H, Miyazono K.
    J Cell Physiol; 2002 Dec 19; 193(3):299-318. PubMed ID: 12384983
    [Abstract] [Full Text] [Related]

  • 5. Distinct regulation of gene expression in human endothelial cells by TGF-beta and its receptors.
    Wu X, Ma J, Han JD, Wang N, Chen YG.
    Microvasc Res; 2006 Jan 19; 71(1):12-9. PubMed ID: 16405919
    [Abstract] [Full Text] [Related]

  • 6. Downregulation of hepatocyte nuclear factor-4alpha and its role in regulation of gene expression by TGF-beta in mammary epithelial cells.
    Ishikawa F, Nose K, Shibanuma M.
    Exp Cell Res; 2008 Jun 10; 314(10):2131-40. PubMed ID: 18433744
    [Abstract] [Full Text] [Related]

  • 7. Characterization of TGF-beta-regulated interleukin-8 expression in human prostate cancer cells.
    Lu S, Dong Z.
    Prostate; 2006 Jun 15; 66(9):996-1004. PubMed ID: 16541418
    [Abstract] [Full Text] [Related]

  • 8. ALK5 promotes tumor angiogenesis by upregulating matrix metalloproteinase-9 in tumor cells.
    Safina A, Vandette E, Bakin AV.
    Oncogene; 2007 Apr 12; 26(17):2407-22. PubMed ID: 17072348
    [Abstract] [Full Text] [Related]

  • 9. TGF-{beta}1 activates two distinct type I receptors in neurons: implications for neuronal NF-{kappa}B signaling.
    König HG, Kögel D, Rami A, Prehn JH.
    J Cell Biol; 2005 Mar 28; 168(7):1077-86. PubMed ID: 15781474
    [Abstract] [Full Text] [Related]

  • 10. Differential responsiveness to autocrine and exogenous transforming growth factor (TGF) beta1 in cells with nonfunctional TGF-beta receptor type III.
    Deng X, Bellis S, Yan Z, Friedman E.
    Cell Growth Differ; 1999 Jan 28; 10(1):11-8. PubMed ID: 9950213
    [Abstract] [Full Text] [Related]

  • 11. Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors.
    Goumans MJ, Valdimarsdottir G, Itoh S, Rosendahl A, Sideras P, ten Dijke P.
    EMBO J; 2002 Apr 02; 21(7):1743-53. PubMed ID: 11927558
    [Abstract] [Full Text] [Related]

  • 12. ALK5 and Smad4 are involved in TGF-beta1-induced pulmonary endothelial permeability.
    Birukova AA, Adyshev D, Gorshkov B, Birukov KG, Verin AD.
    FEBS Lett; 2005 Jul 18; 579(18):4031-7. PubMed ID: 16004987
    [Abstract] [Full Text] [Related]

  • 13. FKBP12 is not required for the modulation of transforming growth factor beta receptor I signaling activity in embryonic fibroblasts and thymocytes.
    Bassing CH, Shou W, Muir S, Heitman J, Matzuk MM, Wang XF.
    Cell Growth Differ; 1998 Mar 18; 9(3):223-8. PubMed ID: 9543388
    [Abstract] [Full Text] [Related]

  • 14. Transforming growth factor-beta receptor requirements for the induction of the endothelin-1 gene.
    Castañares C, Redondo-Horcajo M, Magan-Marchal N, Lamas S, Rodriguez-Pascual F.
    Exp Biol Med (Maywood); 2006 Jun 18; 231(6):700-3. PubMed ID: 16740983
    [Abstract] [Full Text] [Related]

  • 15. SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cells.
    Matsuyama S, Iwadate M, Kondo M, Saitoh M, Hanyu A, Shimizu K, Aburatani H, Mishima HK, Imamura T, Miyazono K, Miyazawa K.
    Cancer Res; 2003 Nov 15; 63(22):7791-8. PubMed ID: 14633705
    [Abstract] [Full Text] [Related]

  • 16. Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathway.
    Yoo YA, Kang MH, Kim JS, Oh SC.
    Carcinogenesis; 2008 Mar 15; 29(3):480-90. PubMed ID: 18174246
    [Abstract] [Full Text] [Related]

  • 17. Fibroblasts from chronic wounds show altered TGF-beta-signaling and decreased TGF-beta Type II receptor expression.
    Kim BC, Kim HT, Park SH, Cha JS, Yufit T, Kim SJ, Falanga V.
    J Cell Physiol; 2003 Jun 15; 195(3):331-6. PubMed ID: 12704642
    [Abstract] [Full Text] [Related]

  • 18. Signaling by ALK5 mediates TGF-beta-induced ET-1 expression in endothelial cells: a role for migration and proliferation.
    Castañares C, Redondo-Horcajo M, Magán-Marchal N, ten Dijke P, Lamas S, Rodríguez-Pascual F.
    J Cell Sci; 2007 Apr 01; 120(Pt 7):1256-66. PubMed ID: 17376964
    [Abstract] [Full Text] [Related]

  • 19. SB-505124 is a selective inhibitor of transforming growth factor-beta type I receptors ALK4, ALK5, and ALK7.
    DaCosta Byfield S, Major C, Laping NJ, Roberts AB.
    Mol Pharmacol; 2004 Mar 01; 65(3):744-52. PubMed ID: 14978253
    [Abstract] [Full Text] [Related]

  • 20. Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice.
    Blaney Davidson EN, Remst DF, Vitters EL, van Beuningen HM, Blom AB, Goumans MJ, van den Berg WB, van der Kraan PM.
    J Immunol; 2009 Jun 15; 182(12):7937-45. PubMed ID: 19494318
    [Abstract] [Full Text] [Related]

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