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353 related items for PubMed ID: 15778702

  • 1. V102862 (Co 102862): a potent, broad-spectrum state-dependent blocker of mammalian voltage-gated sodium channels.
    Ilyin VI, Hodges DD, Whittemore ER, Carter RB, Cai SX, Woodward RM.
    Br J Pharmacol; 2005 Mar; 144(6):801-12. PubMed ID: 15778702
    [Abstract] [Full Text] [Related]

  • 2. Pharmacology of 2-[4-(4-chloro-2-fluorophenoxy)phenyl]-pyrimidine-4-carboxamide: a potent, broad-spectrum state-dependent sodium channel blocker for treating pain states.
    Ilyin VI, Pomonis JD, Whiteside GT, Harrison JE, Pearson MS, Mark L, Turchin PI, Gottshall S, Carter RB, Nguyen P, Hogenkamp DJ, Olanrewaju S, Benjamin E, Woodward RM.
    J Pharmacol Exp Ther; 2006 Sep; 318(3):1083-93. PubMed ID: 16728593
    [Abstract] [Full Text] [Related]

  • 3. Functional and pharmacological properties of human and rat NaV1.8 channels.
    Browne LE, Clare JJ, Wray D.
    Neuropharmacology; 2009 Apr; 56(5):905-14. PubMed ID: 19371587
    [Abstract] [Full Text] [Related]

  • 4. State-dependent inhibition of Na+ currents by the neuroprotective agent 619C89 in rat hippocampal neurons and in a mammalian cell line expressing rat brain type IIA Na+ channels.
    Xie XM, Garthwaite J.
    Neuroscience; 1996 Aug; 73(4):951-62. PubMed ID: 8809814
    [Abstract] [Full Text] [Related]

  • 5. Carisbamate, a novel neuromodulator, inhibits voltage-gated sodium channels and action potential firing of rat hippocampal neurons.
    Liu Y, Yohrling GJ, Wang Y, Hutchinson TL, Brenneman DE, Flores CM, Zhao B.
    Epilepsy Res; 2009 Jan; 83(1):66-72. PubMed ID: 19013768
    [Abstract] [Full Text] [Related]

  • 6. A-887826 is a structurally novel, potent and voltage-dependent Na(v)1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats.
    Zhang XF, Shieh CC, Chapman ML, Matulenko MA, Hakeem AH, Atkinson RN, Kort ME, Marron BE, Joshi S, Honore P, Faltynek CR, Krafte DS, Jarvis MF.
    Neuropharmacology; 2010 Sep; 59(3):201-7. PubMed ID: 20566409
    [Abstract] [Full Text] [Related]

  • 7. The neuroleptic drug, fluphenazine, blocks neuronal voltage-gated sodium channels.
    Zhou X, Dong XW, Priestley T.
    Brain Res; 2006 Aug 23; 1106(1):72-81. PubMed ID: 16839522
    [Abstract] [Full Text] [Related]

  • 8. Characterization of lamotrigine inhibition of Na+ channels in rat hippocampal neurones.
    Kuo CC, Lu L.
    Br J Pharmacol; 1997 Jul 23; 121(6):1231-8. PubMed ID: 9249262
    [Abstract] [Full Text] [Related]

  • 9. Interaction of the antiepileptic drug lamotrigine with recombinant rat brain type IIA Na+ channels and with native Na+ channels in rat hippocampal neurones.
    Xie X, Lancaster B, Peakman T, Garthwaite J.
    Pflugers Arch; 1995 Jul 23; 430(3):437-46. PubMed ID: 7491269
    [Abstract] [Full Text] [Related]

  • 10. Vinpocetine is as potent as phenytoin to block voltage-gated Na+ channels in rat cortical neurons.
    Molnár P, Erdö SL.
    Eur J Pharmacol; 1995 Feb 06; 273(3):303-6. PubMed ID: 7737339
    [Abstract] [Full Text] [Related]

  • 11. Anticonvulsant pharmacology of voltage-gated Na+ channels in hippocampal neurons of control and chronically epileptic rats.
    Remy S, Urban BW, Elger CE, Beck H.
    Eur J Neurosci; 2003 Jun 06; 17(12):2648-58. PubMed ID: 12823472
    [Abstract] [Full Text] [Related]

  • 12. Frequency and voltage-dependent inhibition of type IIA Na+ channels, expressed in a mammalian cell line, by local anesthetic, antiarrhythmic, and anticonvulsant drugs.
    Ragsdale DS, Scheuer T, Catterall WA.
    Mol Pharmacol; 1991 Nov 06; 40(5):756-65. PubMed ID: 1658608
    [Abstract] [Full Text] [Related]

  • 13. Activity of the anticonvulsant lacosamide in experimental and human epilepsy via selective effects on slow Na+ channel inactivation.
    Holtkamp D, Opitz T, Niespodziany I, Wolff C, Beck H.
    Epilepsia; 2017 Jan 06; 58(1):27-41. PubMed ID: 27864845
    [Abstract] [Full Text] [Related]

  • 14. Voltage- and use-dependent inhibition of Na+ channels in rat sensory neurones by 4030W92, a new antihyperalgesic agent.
    Trezise DJ, John VH, Xie XM.
    Br J Pharmacol; 1998 Jul 06; 124(5):953-63. PubMed ID: 9692781
    [Abstract] [Full Text] [Related]

  • 15. Effects of cenobamate (YKP3089), a newly developed anti-epileptic drug, on voltage-gated sodium channels in rat hippocampal CA3 neurons.
    Nakamura M, Cho JH, Shin H, Jang IS.
    Eur J Pharmacol; 2019 Jul 15; 855():175-182. PubMed ID: 31063770
    [Abstract] [Full Text] [Related]

  • 16. Lack of effect of the novel anticonvulsant SB-204269 on voltage-dependent currents in neurones cultured from rat hippocampus.
    Caeser M, Evans ML, Benham CD.
    Neurosci Lett; 1999 Aug 13; 271(1):57-60. PubMed ID: 10471213
    [Abstract] [Full Text] [Related]

  • 17. Inhibitory effect of lamotrigine on A-type potassium current in hippocampal neuron-derived H19-7 cells.
    Huang CW, Huang CC, Liu YC, Wu SN.
    Epilepsia; 2004 Jul 13; 45(7):729-36. PubMed ID: 15230694
    [Abstract] [Full Text] [Related]

  • 18. State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine.
    Wang GK, Calderon J, Wang SY.
    Mol Pharmacol; 2008 Mar 13; 73(3):940-8. PubMed ID: 18079277
    [Abstract] [Full Text] [Related]

  • 19. A disubstituted succinamide is a potent sodium channel blocker with efficacy in a rat pain model.
    Priest BT, Garcia ML, Middleton RE, Brochu RM, Clark S, Dai G, Dick IE, Felix JP, Liu CJ, Reiseter BS, Schmalhofer WA, Shao PP, Tang YS, Chou MZ, Kohler MG, Smith MM, Warren VA, Williams BS, Cohen CJ, Martin WJ, Meinke PT, Parsons WH, Wafford KA, Kaczorowski GJ.
    Biochemistry; 2004 Aug 03; 43(30):9866-76. PubMed ID: 15274641
    [Abstract] [Full Text] [Related]

  • 20. Block of two subtypes of sodium channels in cockroach neurons by indoxacarb insecticides.
    Zhao X, Ikeda T, Salgado VL, Yeh JZ, Narahashi T.
    Neurotoxicology; 2005 Jun 03; 26(3):455-65. PubMed ID: 15935215
    [Abstract] [Full Text] [Related]

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