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Journal Abstract Search

128 related items for PubMed ID: 15780633

  • 1. Good oral absorption prediction on non-nucleoside benzothiadiazine dioxide human cytomegalovirus inhibitors using combined chromatographic and neuronal network techniques.
    Gil C, Dorronsoro I, Castro A, Martinez A.
    Bioorg Med Chem Lett; 2005 Apr 01; 15(7):1919-21. PubMed ID: 15780633
    [Abstract] [Full Text] [Related]

  • 2. Benzothiadiazine dioxides (BTD) derivatives as non-nucleoside human cytomegalovirus (HCMV) inhibitors. study of structural requirements for biological activity.
    Martinez A, Gil C, Castro A, Pérez C, Prieto C, Otero J.
    Bioorg Med Chem; 2003 May 29; 11(11):2395-402. PubMed ID: 12735985
    [Abstract] [Full Text] [Related]

  • 3. Novel potential agents for human cytomegalovirus infection: synthesis and antiviral activity evaluation of benzothiadiazine dioxide acyclonucleosides.
    Martinez A, Esteban AI, Castro A, Gil C, Conde S, Andrei G, Snoeck R, Balzarini J, De Clercq E.
    J Med Chem; 1999 Apr 08; 42(7):1145-50. PubMed ID: 10197958
    [Abstract] [Full Text] [Related]

  • 4. Nonnucleoside human cytomegalovirus inhibitors: synthesis and antiviral evaluation of (chlorophenylmethyl)benzothiadiazine dioxide derivatives.
    Martinez A, Gil C, Perez C, Castro A, Prieto C, Otero J, Andrei G, Snoeck R, Balzarini J, De Clercq E.
    J Med Chem; 2000 Aug 24; 43(17):3267-73. PubMed ID: 10966745
    [Abstract] [Full Text] [Related]

  • 5. Benzothiadiazine dioxide human cytomegalovirus inhibitors: synthesis and antiviral evaluation of main heterocycle modified derivatives.
    Martinez A, Gil C, Castro A, Bruno AM, Pérez C, Prieto C, Otero J.
    Antivir Chem Chemother; 2003 Mar 24; 14(2):107-14. PubMed ID: 12856922
    [Abstract] [Full Text] [Related]

  • 6. Chlorophenylmethyl benzothiadiazine dioxides derivatives: potent human cytomegalovirus inhibitors.
    Martinez A, Gil C, Perez C, Castro A, Prieto C, Otero J.
    Bioorg Med Chem Lett; 1999 Nov 01; 9(21):3133-6. PubMed ID: 10560739
    [Abstract] [Full Text] [Related]

  • 7. Anti-HIV-1 activity of benzothiadiazine dioxide.
    Martinez A, Gil C, Castro A, Perez C, Witvrouw M, Pannecouque C, Balzarini J, De Clercq E.
    Antivir Chem Chemother; 2001 Nov 01; 12(6):347-51. PubMed ID: 12018679
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and biological characterization of B-ring amino analogues of potent benzothiadiazine hepatitis C virus polymerase inhibitors.
    Randolph JT, Flentge CA, Huang PP, Hutchinson DK, Klein LL, Lim HB, Mondal R, Reisch T, Montgomery DA, Jiang WW, Masse SV, Hernandez LE, Henry RF, Liu Y, Koev G, Kati WM, Stewart KD, Beno DW, Molla A, Kempf DJ.
    J Med Chem; 2009 May 28; 52(10):3174-83. PubMed ID: 19402666
    [Abstract] [Full Text] [Related]

  • 9. 4"-Benzoylureido-TSAO derivatives as potent and selective non-nucleoside HCMV inhibitors. Structure-activity relationship and mechanism of antiviral action.
    de Castro S, Peromingo MT, Naesens L, Andrei G, Snoeck R, Balzarini J, Velázquez S, Camarasa MJ.
    J Med Chem; 2008 Sep 25; 51(18):5823-32. PubMed ID: 18707089
    [Abstract] [Full Text] [Related]

  • 10. 4-Benzyloxy-gamma-sultone derivatives: discovery of a novel family of non-nucleoside inhibitors of human cytomegalovirus and varicella zoster virus.
    De Castro S, García-Aparicio C, Andrei G, Snoeck R, Balzarini J, Camarasa MJ, Velázquez S.
    J Med Chem; 2009 Mar 26; 52(6):1582-91. PubMed ID: 19226140
    [Abstract] [Full Text] [Related]

  • 11. Design of translactam HCMV protease inhibitors as potent antivirals.
    Borthwick AD.
    Med Res Rev; 2005 Jul 26; 25(4):427-52. PubMed ID: 15789440
    [Abstract] [Full Text] [Related]

  • 12. Novel inhibitors of human CMV.
    Andrei G, De Clercq E, Snoeck R.
    Curr Opin Investig Drugs; 2008 Feb 26; 9(2):132-45. PubMed ID: 18246516
    [Abstract] [Full Text] [Related]

  • 13. Design and synthesis of pyrrolidine-5,5'-trans-lactams (5-oxo-hexahydropyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 4. Antiviral activity and plasma stability.
    Borthwick AD, Davies DE, Ertl PF, Exall AM, Haley TM, Hart GJ, Jackson DL, Parry NR, Patikis A, Trivedi N, Weingarten GG, Woolven JM.
    J Med Chem; 2003 Oct 09; 46(21):4428-49. PubMed ID: 14521407
    [Abstract] [Full Text] [Related]

  • 14. Human cytomegalovirus DNA replication: antiviral targets and drugs.
    Mercorelli B, Sinigalia E, Loregian A, Palù G.
    Rev Med Virol; 2008 Oct 09; 18(3):177-210. PubMed ID: 18027349
    [Abstract] [Full Text] [Related]

  • 15. 4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as non-nucleoside inhibitors of human cytomegalovirus and related herpesvirus polymerases.
    Schnute ME, Cudahy MM, Brideau RJ, Homa FL, Hopkins TA, Knechtel ML, Oien NL, Pitts TW, Poorman RA, Wathen MW, Wieber JL.
    J Med Chem; 2005 Sep 08; 48(18):5794-804. PubMed ID: 16134946
    [Abstract] [Full Text] [Related]

  • 16. Benzothiadiazine dioxide dibenzyl derivatives as potent human cytomegalovirus inhibitors: synthesis and comparative molecular field analysis.
    Martinez A, Gil C, Abasolo MI, Castro A, Bruno AM, Perez C, Prieto C, Otero J.
    J Med Chem; 2000 Aug 24; 43(17):3218-25. PubMed ID: 10966740
    [Abstract] [Full Text] [Related]

  • 17. Influence of 6 or 8-substitution on the antiviral activity of 3-phenethylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (HCMV) and varicella-zoster virus (VZV).
    Véron JB, Enguehard-Gueiffier C, Snoeck R, Andrei G, De Clercq E, Gueiffier A.
    Bioorg Med Chem; 2007 Nov 15; 15(22):7209-19. PubMed ID: 17869124
    [Abstract] [Full Text] [Related]

  • 18. SAR studies on a novel series of human cytomegalovirus primase inhibitors.
    Chen X, Adrian J, Cushing T, Dimaio H, Liang L, Mayorga V, Miao S, Peterson MG, Powers JP, Spector F, Stein C, Wright M, Xu D, Ye Q, Jaen J.
    Bioorg Med Chem Lett; 2007 Apr 15; 17(8):2188-92. PubMed ID: 17329103
    [Abstract] [Full Text] [Related]

  • 19. Antiviral properties of new arylsulfone derivatives with activity against human betaherpesviruses.
    Naesens L, Stephens CE, Andrei G, Loregian A, De Bolle L, Snoeck R, Sowell JW, De Clercq E.
    Antiviral Res; 2006 Oct 15; 72(1):60-7. PubMed ID: 16650489
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and antiviral evaluation of alkoxyalkyl derivatives of 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine against cytomegalovirus and orthopoxviruses.
    Beadle JR, Wan WB, Ciesla SL, Keith KA, Hartline C, Kern ER, Hostetler KY.
    J Med Chem; 2006 Mar 23; 49(6):2010-5. PubMed ID: 16539388
    [Abstract] [Full Text] [Related]

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