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616 related items for PubMed ID: 15782132

  • 1. Rapamycin induces apoptosis of JN-DSRCT-1 cells by increasing the Bax : Bcl-xL ratio through concurrent mechanisms dependent and independent of its mTOR inhibitory activity.
    Tirado OM, Mateo-Lozano S, Notario V.
    Oncogene; 2005 May 05; 24(20):3348-57. PubMed ID: 15782132
    [Abstract] [Full Text] [Related]

  • 2. Rapamycin induces the fusion-type independent downregulation of the EWS/FLI-1 proteins and inhibits Ewing's sarcoma cell proliferation.
    Mateo-Lozano S, Tirado OM, Notario V.
    Oncogene; 2003 Dec 18; 22(58):9282-7. PubMed ID: 14681687
    [Abstract] [Full Text] [Related]

  • 3. Suppression of human prostate cancer cell growth by ciprofloxacin is associated with cell cycle arrest and apoptosis.
    Aranha O, Grignon R, Fernandes N, McDonnell TJ, Wood DP, Sarkar FH.
    Int J Oncol; 2003 Apr 18; 22(4):787-94. PubMed ID: 12632069
    [Abstract] [Full Text] [Related]

  • 4. Rapamycin inhibits cell growth by induction of apoptosis on hepatocellular carcinoma cells in vitro.
    Zhang JF, Liu JJ, Lu MQ, Cai CJ, Yang Y, Li H, Xu C, Chen GH.
    Transpl Immunol; 2007 Apr 18; 17(3):162-8. PubMed ID: 17331842
    [Abstract] [Full Text] [Related]

  • 5. Damaged microtubules can inactivate BCL-2 by means of the mTOR kinase.
    Calastretti A, Bevilacqua A, Ceriani C, Viganò S, Zancai P, Capaccioli S, Nicolin A.
    Oncogene; 2001 Sep 27; 20(43):6172-80. PubMed ID: 11593425
    [Abstract] [Full Text] [Related]

  • 6. Rapamycin causes poorly reversible inhibition of mTOR and induces p53-independent apoptosis in human rhabdomyosarcoma cells.
    Hosoi H, Dilling MB, Shikata T, Liu LN, Shu L, Ashmun RA, Germain GS, Abraham RT, Houghton PJ.
    Cancer Res; 1999 Feb 15; 59(4):886-94. PubMed ID: 10029080
    [Abstract] [Full Text] [Related]

  • 7. The rapamycin-sensitive signal transduction pathway as a target for cancer therapy.
    Hidalgo M, Rowinsky EK.
    Oncogene; 2000 Dec 27; 19(56):6680-6. PubMed ID: 11426655
    [Abstract] [Full Text] [Related]

  • 8. Pharmacodynamic Evaluation of CCI-779, an Inhibitor of mTOR, in Cancer Patients.
    Peralba JM, DeGraffenried L, Friedrichs W, Fulcher L, Grünwald V, Weiss G, Hidalgo M.
    Clin Cancer Res; 2003 Aug 01; 9(8):2887-92. PubMed ID: 12912932
    [Abstract] [Full Text] [Related]

  • 9. Mechanism by which mammalian target of rapamycin inhibitors sensitize multiple myeloma cells to dexamethasone-induced apoptosis.
    Yan H, Frost P, Shi Y, Hoang B, Sharma S, Fisher M, Gera J, Lichtenstein A.
    Cancer Res; 2006 Feb 15; 66(4):2305-13. PubMed ID: 16489035
    [Abstract] [Full Text] [Related]

  • 10. Bcl-XL protein is markedly decreased in UVB-irradiated basal cell carcinoma cell lines through proteasome-mediated degradation.
    Park K, Lee JH.
    Oncol Rep; 2009 Mar 15; 21(3):689-92. PubMed ID: 19212627
    [Abstract] [Full Text] [Related]

  • 11. Suppression of chondrosarcoma cells by 15-deoxy-Delta 12,14-prostaglandin J2 is associated with altered expression of Bax/Bcl-xL and p21.
    Shen ZN, Nishida K, Doi H, Oohashi T, Hirohata S, Ozaki T, Yoshida A, Ninomiya Y, Inoue H.
    Biochem Biophys Res Commun; 2005 Mar 11; 328(2):375-82. PubMed ID: 15694358
    [Abstract] [Full Text] [Related]

  • 12. The cyclin-dependent kinase inhibitor flavopiridol induces apoptosis in multiple myeloma cells through transcriptional repression and down-regulation of Mcl-1.
    Gojo I, Zhang B, Fenton RG.
    Clin Cancer Res; 2002 Nov 11; 8(11):3527-38. PubMed ID: 12429644
    [Abstract] [Full Text] [Related]

  • 13. Induction of apoptosis and cell cycle arrest by a chalcone panduratin A isolated from Kaempferia pandurata in androgen-independent human prostate cancer cells PC3 and DU145.
    Yun JM, Kweon MH, Kwon H, Hwang JK, Mukhtar H.
    Carcinogenesis; 2006 Jul 11; 27(7):1454-64. PubMed ID: 16497706
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of the mammalian target of rapamycin (mTOR) by rapamycin increases chemosensitivity of CaSki cells to paclitaxel.
    Faried LS, Faried A, Kanuma T, Nakazato T, Tamura T, Kuwano H, Minegishi T.
    Eur J Cancer; 2006 May 11; 42(7):934-47. PubMed ID: 16540312
    [Abstract] [Full Text] [Related]

  • 15. Absence of Bcl-xL down-regulation in response to cisplatin is associated with chemoresistance in ovarian carcinoma cells.
    Villedieu M, Louis MH, Dutoit S, Brotin E, Lincet H, Duigou F, Staedel C, Gauduchon P, Poulain L.
    Gynecol Oncol; 2007 Apr 11; 105(1):31-44. PubMed ID: 17275076
    [Abstract] [Full Text] [Related]

  • 16. Bcl-2 and CCND1/CDK4 expression levels predict the cellular effects of mTOR inhibitors in human ovarian carcinoma.
    Aguirre D, Boya P, Bellet D, Faivre S, Troalen F, Benard J, Saulnier P, Hopkins-Donaldson S, Zangemeister-Wittke U, Kroemer G, Raymond E.
    Apoptosis; 2004 Nov 11; 9(6):797-805. PubMed ID: 15505422
    [Abstract] [Full Text] [Related]

  • 17. Bcl-XL induction during terminal differentiation of friend erythroleukaemia cells correlates with delay of apoptosis and loss of proliferative capacity but not with haemoglobinization.
    Hafid-Medheb K, Poindessous-Jazat V, Augery-Bourget Y, Hanania N, Robert-Lézénès J.
    Cell Death Differ; 1999 Feb 11; 6(2):166-74. PubMed ID: 10200563
    [Abstract] [Full Text] [Related]

  • 18. Taxol and estramustine-induced modulation of human prostate cancer cell apoptosis via alteration in bcl-xL and bak expression.
    Liu QY, Stein CA.
    Clin Cancer Res; 1997 Nov 11; 3(11):2039-46. PubMed ID: 9815595
    [Abstract] [Full Text] [Related]

  • 19. Tannic acid potently inhibits tumor cell proteasome activity, increases p27 and Bax expression, and induces G1 arrest and apoptosis.
    Nam S, Smith DM, Dou QP.
    Cancer Epidemiol Biomarkers Prev; 2001 Oct 11; 10(10):1083-8. PubMed ID: 11588135
    [Abstract] [Full Text] [Related]

  • 20. A novel bispecific antisense oligonucleotide inhibiting both bcl-2 and bcl-xL expression efficiently induces apoptosis in tumor cells.
    Zangemeister-Wittke U, Leech SH, Olie RA, Simões-Wüst AP, Gautschi O, Luedke GH, Natt F, Häner R, Martin P, Hall J, Nalin CM, Stahel RA.
    Clin Cancer Res; 2000 Jun 11; 6(6):2547-55. PubMed ID: 10873111
    [Abstract] [Full Text] [Related]

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