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Journal Abstract Search

111 related items for PubMed ID: 15788365

  • 1. Metabolism of benzamidoxime (N-hydroxyamidine) in human hepatocytes and role of UDP-glucuronosyltransferases.
    Fröhlich AK, Girreser U, Clement B.
    Xenobiotica; 2005 Jan; 35(1):17-25. PubMed ID: 15788365
    [Abstract] [Full Text] [Related]

  • 2. Metabolism of N-hydroxyguanidines (N-hydroxydebrisoquine) in human and porcine hepatocytes: reduction and formation of glucuronides.
    Froehlich AK, Girreser U, Clement B.
    Drug Metab Dispos; 2005 Oct; 33(10):1532-7. PubMed ID: 16033947
    [Abstract] [Full Text] [Related]

  • 3. Phase 2 metabolites of N-hydroxylated amidines (amidoximes): synthesis, in vitro formation by pig hepatocytes, and mutagenicity testing.
    Clement B, Christiansen K, Girreser U.
    Chem Res Toxicol; 2001 Mar; 14(3):319-26. PubMed ID: 11258982
    [Abstract] [Full Text] [Related]

  • 4. N-glucuronidation of nicotine and cotinine in human: formation of cotinine glucuronide in liver microsomes and lack of catalysis by 10 examined UDP-glucuronosyltransferases.
    Ghosheh O, Hawes EM.
    Drug Metab Dispos; 2002 Sep; 30(9):991-6. PubMed ID: 12167564
    [Abstract] [Full Text] [Related]

  • 5. Direct comparison of UDP-glucuronosyltransferase and cytochrome P450 activities in human liver microsomes, plated and suspended primary human hepatocytes from five liver donors.
    den Braver-Sewradj SP, den Braver MW, Baze A, Decorde J, Fonsi M, Bachellier P, Vermeulen NPE, Commandeur JNM, Richert L, Vos JC.
    Eur J Pharm Sci; 2017 Nov 15; 109():96-110. PubMed ID: 28778465
    [Abstract] [Full Text] [Related]

  • 6. Biotransformation of benzamidine and benzamidoxime in vivo.
    Clement B, Immel M, Schmitt S, Steinmann U.
    Arch Pharm (Weinheim); 1993 Oct 15; 326(10):807-12. PubMed ID: 8267515
    [Abstract] [Full Text] [Related]

  • 7. In vitro glucuronidation of thyroxine and triiodothyronine by liver microsomes and recombinant human UDP-glucuronosyltransferases.
    Tong Z, Li H, Goljer I, McConnell O, Chandrasekaran A.
    Drug Metab Dispos; 2007 Dec 15; 35(12):2203-10. PubMed ID: 17875670
    [Abstract] [Full Text] [Related]

  • 8. Genotoxic activities of benzamidine and its N-hydroxylated metabolite benzamidoxime in Salmonella typhimurium and mammalian cells.
    Clement B, Schmezer P, Weber H, Schlehofer JR, Schmitt S, Pool BL.
    J Cancer Res Clin Oncol; 1988 Dec 15; 114(4):363-8. PubMed ID: 3045129
    [Abstract] [Full Text] [Related]

  • 9. Glucuronidation of edaravone by human liver and kidney microsomes: biphasic kinetics and identification of UGT1A9 as the major UDP-glucuronosyltransferase isoform.
    Ma L, Sun J, Peng Y, Zhang R, Shao F, Hu X, Zhu J, Wang X, Cheng X, Zhu Y, Wan P, Feng D, Wu H, Wang G.
    Drug Metab Dispos; 2012 Apr 15; 40(4):734-41. PubMed ID: 22238289
    [Abstract] [Full Text] [Related]

  • 10. Glucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10.
    Ramírez J, Mirkov S, House LK, Ratain MJ.
    Drug Metab Dispos; 2015 Jul 15; 43(7):928-35. PubMed ID: 25870101
    [Abstract] [Full Text] [Related]

  • 11. Involvement of multiple UDP-glucuronosyltransferase 1A isoforms in glucuronidation of 5-(4'-hydroxyphenyl)-5-phenylhydantoin in human liver microsomes.
    Nakajima M, Sakata N, Ohashi N, Kume T, Yokoi T.
    Drug Metab Dispos; 2002 Nov 15; 30(11):1250-6. PubMed ID: 12386132
    [Abstract] [Full Text] [Related]

  • 12. Regioselective glucuronidation of the isoflavone calycosin by human liver microsomes and recombinant human UDP-glucuronosyltransferases.
    Ruan JQ, Yan R.
    Chem Biol Interact; 2014 Sep 05; 220():231-40. PubMed ID: 25044472
    [Abstract] [Full Text] [Related]

  • 13. Evidence for differences in regioselective and stereoselective glucuronidation of silybin diastereomers from milk thistle (Silybum marianum) by human UDP-glucuronosyltransferases.
    Jančová P, Siller M, Anzenbacherová E, Křen V, Anzenbacher P, Simánek V.
    Xenobiotica; 2011 Sep 05; 41(9):743-51. PubMed ID: 21524189
    [Abstract] [Full Text] [Related]

  • 14. Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples.
    Brand W, Boersma MG, Bik H, Hoek-van den Hil EF, Vervoort J, Barron D, Meinl W, Glatt H, Williamson G, van Bladeren PJ, Rietjens IM.
    Drug Metab Dispos; 2010 Apr 05; 38(4):617-25. PubMed ID: 20056724
    [Abstract] [Full Text] [Related]

  • 15. Involvement of UDP-glucuronosyltransferases UGT1A9 and UGT2B7 in ethanol glucuronidation, and interactions with common drugs of abuse.
    Al Saabi A, Allorge D, Sauvage FL, Tournel G, Gaulier JM, Marquet P, Picard N.
    Drug Metab Dispos; 2013 Mar 05; 41(3):568-74. PubMed ID: 23230132
    [Abstract] [Full Text] [Related]

  • 16. [Biotransformation of benzamidine and benzamidoxime by microsomal enzymes of the rabbit].
    Clement B, Zimmermann M, Schmitt S.
    Arch Pharm (Weinheim); 1989 Jul 05; 322(7):431-5. PubMed ID: 2783015
    [Abstract] [Full Text] [Related]

  • 17. Imipramine N-glucuronidation in human liver microsomes: biphasic kinetics and characterization of UDP-glucuronosyltransferase isoforms.
    Nakajima M, Tanaka E, Kobayashi T, Ohashi N, Kume T, Yokoi T.
    Drug Metab Dispos; 2002 Jun 05; 30(6):636-42. PubMed ID: 12019188
    [Abstract] [Full Text] [Related]

  • 18. Quaternary ammonium-linked glucuronidation of trans-4-hydroxytamoxifen, an active metabolite of tamoxifen, by human liver microsomes and UDP-glucuronosyltransferase 1A4.
    Ogura K, Ishikawa Y, Kaku T, Nishiyama T, Ohnuma T, Muro K, Hiratsuka A.
    Biochem Pharmacol; 2006 Apr 28; 71(9):1358-69. PubMed ID: 16480962
    [Abstract] [Full Text] [Related]

  • 19. Hepatic UDP-glucuronosyltransferases responsible for glucuronidation of thyroxine in humans.
    Kato Y, Ikushiro S, Emi Y, Tamaki S, Suzuki H, Sakaki T, Yamada S, Degawa M.
    Drug Metab Dispos; 2008 Jan 28; 36(1):51-5. PubMed ID: 17908920
    [Abstract] [Full Text] [Related]

  • 20. Hepatic, extrahepatic, microsomal, and mitochondrial activation of the N-hydroxylated prodrugs benzamidoxime, guanoxabenz, and Ro 48-3656 ([[1-[(2s)-2-[[4-[(hydroxyamino)iminomethyl]benzoyl]amino]-1-oxopropyl]-4-piperidinyl]oxy]-acetic acid).
    Clement B, Mau S, Deters S, Havemeyer A.
    Drug Metab Dispos; 2005 Nov 28; 33(11):1740-7. PubMed ID: 16118330
    [Abstract] [Full Text] [Related]

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