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355 related items for PubMed ID: 15788389

  • 1. Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis.
    Guo RT, Ko TP, Chen AP, Kuo CJ, Wang AH, Liang PH.
    J Biol Chem; 2005 May 27; 280(21):20762-74. PubMed ID: 15788389
    [Abstract] [Full Text] [Related]

  • 2. Substrate binding mode and reaction mechanism of undecaprenyl pyrophosphate synthase deduced from crystallographic studies.
    Chang SY, Ko TP, Chen AP, Wang AH, Liang PH.
    Protein Sci; 2004 Apr 27; 13(4):971-8. PubMed ID: 15044730
    [Abstract] [Full Text] [Related]

  • 3. Substrate and product specificities of cis-type undecaprenyl pyrophosphate synthase.
    Chen AP, Chang SY, Lin YC, Sun YS, Chen CT, Wang AH, Liang PH.
    Biochem J; 2005 Feb 15; 386(Pt 1):169-76. PubMed ID: 15447632
    [Abstract] [Full Text] [Related]

  • 4. Catalytic mechanism revealed by the crystal structure of undecaprenyl pyrophosphate synthase in complex with sulfate, magnesium, and triton.
    Chang SY, Ko TP, Liang PH, Wang AH.
    J Biol Chem; 2003 Aug 01; 278(31):29298-307. PubMed ID: 12756244
    [Abstract] [Full Text] [Related]

  • 5. Mechanism of cis-prenyltransferase reaction probed by substrate analogues.
    Lu YP, Liu HG, Teng KH, Liang PH.
    Biochem Biophys Res Commun; 2010 Oct 01; 400(4):758-62. PubMed ID: 20828539
    [Abstract] [Full Text] [Related]

  • 6. Product distribution and pre-steady-state kinetic analysis of Escherichia coli undecaprenyl pyrophosphate synthase reaction.
    Pan JJ, Chiou ST, Liang PH.
    Biochemistry; 2000 Sep 05; 39(35):10936-42. PubMed ID: 10978182
    [Abstract] [Full Text] [Related]

  • 7. Effect of site-directed mutagenesis of the conserved aspartate and glutamate on E. coli undecaprenyl pyrophosphate synthase catalysis.
    Pan JJ, Yang LW, Liang PH.
    Biochemistry; 2000 Nov 14; 39(45):13856-61. PubMed ID: 11076526
    [Abstract] [Full Text] [Related]

  • 8. Probing the conformational change of Escherichia coli undecaprenyl pyrophosphate synthase during catalysis using an inhibitor and tryptophan mutants.
    Chen YH, Chen AP, Chen CT, Wang AH, Liang PH.
    J Biol Chem; 2002 Mar 01; 277(9):7369-76. PubMed ID: 11744728
    [Abstract] [Full Text] [Related]

  • 9. Undecaprenyl diphosphate synthase, a cis-prenyltransferase synthesizing lipid carrier for bacterial cell wall biosynthesis.
    Teng KH, Liang PH.
    Mol Membr Biol; 2012 Nov 01; 29(7):267-73. PubMed ID: 22471620
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and application of a fluorescent substrate analogue to study ligand interactions for undecaprenyl pyrophosphate synthase.
    Chen AP, Chen YH, Liu HP, Li YC, Chen CT, Liang PH.
    J Am Chem Soc; 2002 Dec 25; 124(51):15217-24. PubMed ID: 12487597
    [Abstract] [Full Text] [Related]

  • 11. Modeling studies with Helicobacter pylori octaprenyl pyrophosphate synthase reveal the enzymatic mechanism of trans-prenyltransferases.
    Zhang J, Zhang X, Zhang R, Wu C, Guo Y, Mao X, Guo G, Zhang Y, Wang DC, Li D, Zou Q.
    Int J Biochem Cell Biol; 2012 Dec 25; 44(12):2116-23. PubMed ID: 22982238
    [Abstract] [Full Text] [Related]

  • 12. Structures, mechanisms and inhibitors of undecaprenyl diphosphate synthase: a cis-prenyltransferase for bacterial peptidoglycan biosynthesis.
    Teng KH, Liang PH.
    Bioorg Chem; 2012 Aug 25; 43():51-7. PubMed ID: 21993493
    [Abstract] [Full Text] [Related]

  • 13. Identification of the active conformation and the importance of length of the flexible loop 72-83 in regulating the conformational change of undecaprenyl pyrophosphate synthase.
    Chang SY, Chen YK, Wang AH, Liang PH.
    Biochemistry; 2003 Dec 16; 42(49):14452-9. PubMed ID: 14661956
    [Abstract] [Full Text] [Related]

  • 14. Biophysical investigation of the mode of inhibition of tetramic acids, the allosteric inhibitors of undecaprenyl pyrophosphate synthase.
    Lee LV, Granda B, Dean K, Tao J, Liu E, Zhang R, Peukert S, Wattanasin S, Xie X, Ryder NS, Tommasi R, Deng G.
    Biochemistry; 2010 Jun 29; 49(25):5366-76. PubMed ID: 20476728
    [Abstract] [Full Text] [Related]

  • 15. Different reaction mechanisms for cis- and trans-prenyltransferases.
    Lu YP, Liu HG, Liang PH.
    Biochem Biophys Res Commun; 2009 Feb 06; 379(2):351-5. PubMed ID: 19103164
    [Abstract] [Full Text] [Related]

  • 16. Mechanism of product chain length determination and the role of a flexible loop in Escherichia coli undecaprenyl-pyrophosphate synthase catalysis.
    Ko TP, Chen YK, Robinson H, Tsai PC, Gao YG, Chen AP, Wang AH, Liang PH.
    J Biol Chem; 2001 Dec 14; 276(50):47474-82. PubMed ID: 11581264
    [Abstract] [Full Text] [Related]

  • 17. Insight into the activation mechanism of Escherichia coli octaprenyl pyrophosphate synthase derived from pre-steady-state kinetic analysis.
    Pan JJ, Kuo TH, Chen YK, Yang LW, Liang PH.
    Biochim Biophys Acta; 2002 Jan 31; 1594(1):64-73. PubMed ID: 11825609
    [Abstract] [Full Text] [Related]

  • 18. Discovery and structural characterization of an allosteric inhibitor of bacterial cis-prenyltransferase.
    Danley DE, Baima ET, Mansour M, Fennell KF, Chrunyk BA, Mueller JP, Liu S, Qiu X.
    Protein Sci; 2015 Jan 31; 24(1):20-6. PubMed ID: 25287857
    [Abstract] [Full Text] [Related]

  • 19. Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms.
    Han X, Chen CC, Kuo CJ, Huang CH, Zheng Y, Ko TP, Zhu Z, Feng X, Wang K, Oldfield E, Wang AH, Liang PH, Guo RT, Ma Y.
    Proteins; 2015 Jan 31; 83(1):37-45. PubMed ID: 24895191
    [Abstract] [Full Text] [Related]

  • 20. Significance of highly conserved aromatic residues in Micrococcus luteus B-P 26 undecaprenyl diphosphate synthase.
    Kharel Y, Zhang YW, Fujihashi M, Miki K, Koyama T.
    J Biochem; 2003 Dec 31; 134(6):819-26. PubMed ID: 14769870
    [Abstract] [Full Text] [Related]

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