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Journal Abstract Search

423 related items for PubMed ID: 15808402

  • 1. Lamellarin D: a novel pro-apoptotic agent from marine origin insensitive to P-glycoprotein-mediated drug efflux.
    Vanhuyse M, Kluza J, Tardy C, Otero G, Cuevas C, Bailly C, Lansiaux A.
    Cancer Lett; 2005 Apr 28; 221(2):165-75. PubMed ID: 15808402
    [Abstract] [Full Text] [Related]

  • 2. Lamellarin D: a novel potent inhibitor of topoisomerase I.
    Facompré M, Tardy C, Bal-Mahieu C, Colson P, Perez C, Manzanares I, Cuevas C, Bailly C.
    Cancer Res; 2003 Nov 01; 63(21):7392-9. PubMed ID: 14612538
    [Abstract] [Full Text] [Related]

  • 3. Cancer cell mitochondria are direct proapoptotic targets for the marine antitumor drug lamellarin D.
    Kluza J, Gallego MA, Loyens A, Beauvillain JC, Sousa-Faro JM, Cuevas C, Marchetti P, Bailly C.
    Cancer Res; 2006 Mar 15; 66(6):3177-87. PubMed ID: 16540669
    [Abstract] [Full Text] [Related]

  • 4. Topoisomerase I-mediated DNA cleavage as a guide to the development of antitumor agents derived from the marine alkaloid lamellarin D: triester derivatives incorporating amino acid residues.
    Tardy C, Facompré M, Laine W, Baldeyrou B, García-Gravalos D, Francesch A, Mateo C, Pastor A, Jiménez JA, Manzanares I, Cuevas C, Bailly C.
    Bioorg Med Chem; 2004 Apr 01; 12(7):1697-712. PubMed ID: 15028262
    [Abstract] [Full Text] [Related]

  • 5. Essential role of mitochondria in apoptosis of cancer cells induced by the marine alkaloid Lamellarin D.
    Ballot C, Kluza J, Martoriati A, Nyman U, Formstecher P, Joseph B, Bailly C, Marchetti P.
    Mol Cancer Ther; 2009 Dec 01; 8(12):3307-17. PubMed ID: 19952118
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and biological evaluation of a D-ring-contracted analogue of lamellarin D.
    Colligs V, Hansen SP, Imbri D, Seo EJ, Kadioglu O, Efferth T, Opatz T.
    Bioorg Med Chem; 2017 Nov 15; 25(22):6137-6148. PubMed ID: 28233677
    [Abstract] [Full Text] [Related]

  • 7. Vinflunine (20',20'-difluoro-3',4'-dihydrovinorelbine), a novel Vinca alkaloid, which participates in P-glycoprotein (Pgp)-mediated multidrug resistance in vivo and in vitro.
    Etievant C, Barret JM, Kruczynski A, Perrin D, Hill BT.
    Invest New Drugs; 1998 Nov 15; 16(1):3-17. PubMed ID: 9740539
    [Abstract] [Full Text] [Related]

  • 8. Poisoning of mitochondrial topoisomerase I by lamellarin D.
    Khiati S, Seol Y, Agama K, Dalla Rosa I, Agrawal S, Fesen K, Zhang H, Neuman KC, Pommier Y.
    Mol Pharmacol; 2014 Aug 15; 86(2):193-9. PubMed ID: 24890608
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of mitochondrial respiration mediates apoptosis induced by the anti-tumoral alkaloid lamellarin D.
    Ballot C, Kluza J, Lancel S, Martoriati A, Hassoun SM, Mortier L, Vienne JC, Briand G, Formstecher P, Bailly C, Nevière R, Marchetti P.
    Apoptosis; 2010 Jul 15; 15(7):769-81. PubMed ID: 20151196
    [Abstract] [Full Text] [Related]

  • 10. Medicarpin and millepurpan, two flavonoids isolated from Medicago sativa, induce apoptosis and overcome multidrug resistance in leukemia P388 cells.
    Gatouillat G, Magid AA, Bertin E, El btaouri H, Morjani H, Lavaud C, Madoulet C.
    Phytomedicine; 2015 Dec 01; 22(13):1186-94. PubMed ID: 26598918
    [Abstract] [Full Text] [Related]

  • 11. Difference between the resistance mechanisms of aclacinomycin- and adriamycin-resistant P388 cell lines.
    Dong J, Naito M, Tatsuta T, Seimiya H, Johdo O, Tsuruo T.
    Oncol Res; 1995 Dec 01; 7(5):245-52. PubMed ID: 8534930
    [Abstract] [Full Text] [Related]

  • 12. Development of a stable camptothecin-resistant subline of P388 leukemia with reduced topoisomerase I content.
    Eng WK, McCabe FL, Tan KB, Mattern MR, Hofmann GA, Woessner RD, Hertzberg RP, Johnson RK.
    Mol Pharmacol; 1990 Oct 01; 38(4):471-80. PubMed ID: 2172765
    [Abstract] [Full Text] [Related]

  • 13. Cytotoxicity, apoptosis induction and downregulation of MDR-1 expression by the anti-topoisomerase II agent, salvicine, in multidrug-resistant tumor cells.
    Miao ZH, Tang T, Zhang YX, Zhang JS, Ding J.
    Int J Cancer; 2003 Aug 10; 106(1):108-15. PubMed ID: 12794765
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and structure-activity relationship study of potent cytotoxic analogues of the marine alkaloid Lamellarin D.
    Pla D, Marchal A, Olsen CA, Francesch A, Cuevas C, Albericio F, Alvarez M.
    J Med Chem; 2006 Jun 01; 49(11):3257-68. PubMed ID: 16722644
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of topoisomerase II by the marine alkaloid ascididemin and induction of apoptosis in leukemia cells.
    Dassonneville L, Wattez N, Baldeyrou B, Mahieu C, Lansiaux A, Banaigs B, Bonnard I, Bailly C.
    Biochem Pharmacol; 2000 Aug 15; 60(4):527-37. PubMed ID: 10874127
    [Abstract] [Full Text] [Related]

  • 16. Decreased nucleotide excision repair activity and alterations of topoisomerase IIalpha are associated with the in vivo resistance of a P388 leukemia subline to F11782, a novel catalytic inhibitor of topoisomerases I and II.
    Kruczynski A, Barret JM, Van Hille B, Chansard N, Astruc J, Menon Y, Duchier C, Créancier L, Hill BT.
    Clin Cancer Res; 2004 May 01; 10(9):3156-68. PubMed ID: 15131057
    [Abstract] [Full Text] [Related]

  • 17. Decreased DNA topoisomerase II alpha expression and cold-sensitive growth in a mouse mammary cancer cell line resistant to etoposide and doxorubicin.
    Kawanami K, Nakamura T, Ono M, Kusano T, Okada K, Kikuchi A, Adachi N, Kohno K, Higashi K, Kuwano M.
    Oncol Res; 1996 May 01; 8(5):197-206. PubMed ID: 8884812
    [Abstract] [Full Text] [Related]

  • 18. Major contribution of the multidrug transporter P-glycoprotein to reduced susceptibility of poly(ADP-ribose) polymerase-1 knock-out cells to doxorubicin action.
    Wesierska-Gadek J.
    J Cell Biochem; 2005 Aug 01; 95(5):1012-28. PubMed ID: 15861398
    [Abstract] [Full Text] [Related]

  • 19. Reversal of P-glycoprotein-mediated multidrug resistance by guggulsterone in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells.
    Xu HB, Li L, Liu GQ.
    Pharmazie; 2009 Oct 01; 64(10):660-5. PubMed ID: 19947169
    [Abstract] [Full Text] [Related]

  • 20. Polyaromatic alkaloids from marine invertebrates as cytotoxic compounds and inhibitors of multidrug resistance caused by P-glycoprotein.
    Quesada AR, García Grávalos MD, Fernández Puentes JL.
    Br J Cancer; 1996 Sep 01; 74(5):677-82. PubMed ID: 8795567
    [Abstract] [Full Text] [Related]

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