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Journal Abstract Search

235 related items for PubMed ID: 15819385

  • 1. Pharmacokinetics and disposition of DY-9760e, a novel calmodulin antagonist, in rats and monkeys.
    Tachibana S, Fujimaki Y, Tachibana M, Tanaka M, Kurata T, Okazaki O, Sudo K.
    Arzneimittelforschung; 2005; 55(3):135-44. PubMed ID: 15819385
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  • 2. 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e), a novel calmodulin antagonist, reduces brain edema through the inhibition of enhanced blood-brain barrier permeability after transient focal ischemia.
    Sato T, Morishima Y, Shirasaki Y.
    J Pharmacol Exp Ther; 2003 Mar; 304(3):1042-7. PubMed ID: 12604680
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  • 4. Absorption, distribution and excretion of [carbonyl-14C]mosapride citrate after a single oral administration in rats, dogs and monkeys.
    Matsumoto S, Tagawa M, Amejima H, Nakao M, Kagemoto A, Fujii T, Miyazaki H, Sekine Y.
    Arzneimittelforschung; 1993 Oct; 43(10):1084-94. PubMed ID: 8267675
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  • 5. Inhibition of dystrophin breakdown and endothelial nitric-oxide synthase uncoupling accounts for cytoprotection by 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e) in left ventricular hypertrophied Mice.
    Han F, Lu YM, Hasegawa H, Kanai H, Hachimura E, Shirasaki Y, Fukunaga K.
    J Pharmacol Exp Ther; 2010 Feb; 332(2):421-8. PubMed ID: 19889795
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  • 6. 3-[2-[4-(3-Chloro-2-methylphenylmethyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydro-chloride 3.5 hydrate (DY-9760e) is neuroprotective in rat microsphere embolism: role of the cross-talk between calpain and caspase-3 through calpastatin.
    Han F, Shirasaki Y, Fukunaga K.
    J Pharmacol Exp Ther; 2006 May; 317(2):529-36. PubMed ID: 16467455
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  • 7. Post-ischemic administration of DY-9760e, a novel calmodulin antagonist, reduced infarct volume in the permanent focal ischemia model of spontaneously hypertensive rat.
    Takagi K, Sato T, Shirasaki Y, Narita K, Tamura A, Sano K.
    Neurol Res; 2001 Sep; 23(6):662-8. PubMed ID: 11547940
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  • 8. Pharmacokinetics of the new thyrotropin releasing hormone analogue montirelin hydrate. 1st communication: plasma concentrations, metabolism and excretion after a single intravenous administration to rats, dogs and monkeys.
    Sugimoto T, Hayashi T, Okita A, Morino A.
    Arzneimittelforschung; 1996 Feb; 46(2):106-13. PubMed ID: 8720298
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  • 9. DY-9760e, a novel calmodulin antagonist, reduces brain damage induced by transient focal cerebral ischemia.
    Sato T, Morishima Y, Sugimura M, Uchida T, Shirasaki Y.
    Eur J Pharmacol; 1999 Apr 09; 370(2):117-23. PubMed ID: 10323259
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  • 10. Pharmacokinetics of NS-105, a novel cognition enhancer. 1st communication: absorption, metabolism and excretion in rats, dogs and monkeys after single administration of 14C-NS-105.
    Mukai H, Sugimoto T, Ago M, Morino A.
    Arzneimittelforschung; 1999 Nov 09; 49(11):881-90. PubMed ID: 10604039
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  • 11. The post-ischemic administration of 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e), a novel calmodulin antagonist, prevents delayed neuronal death in gerbil hippocampus.
    Hashiguchi A, Yano S, Morioka M, Hamada J, Shirasaki Y, Kochi M, Fukunaga K.
    J Pharmacol Sci; 2004 Sep 09; 96(1):65-72. PubMed ID: 15359085
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  • 13. The neuroprotective effect of a novel calmodulin antagonist, 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate, in transient forebrain ischemia.
    Hashiguchi A, Kawano T, Yano S, Morioka M, Hamada J, Sato T, Shirasaki Y, Ushio Y, Fukunaga K.
    Neuroscience; 2003 Sep 09; 121(2):379-86. PubMed ID: 14521996
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  • 15. DY-9760e, a calmodulin antagonist, reduces brain damage after permanent focal cerebral ischemia in cats.
    Sugimura M, Takamori H, Fukushi H, Kitano Y, Kanazawa Y, Shirasaki Y.
    Biol Pharm Bull; 2005 Apr 09; 28(4):629-33. PubMed ID: 15802800
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  • 17. DY-9760e, a novel calmodulin antagonist with cytoprotective action.
    Sugimura M, Sato T, Nakayama W, Morishima Y, Fukunaga K, Omitsu M, Miyamoto E, Shirasaki Y.
    Eur J Pharmacol; 1997 Oct 01; 336(1):99-106. PubMed ID: 9384259
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