These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

849 related items for PubMed ID: 15823578

  • 1. Binding affinity difference induced by the stereochemistry of the sulfoxide bridge of the cyclic peptide inhibitors of Grb2-SH2 domain: NMR studies for the structural origin.
    Shi YH, Song YL, Lin DH, Tan J, Roller PP, Li Q, Long YQ, Song GQ.
    Biochem Biophys Res Commun; 2005 May 20; 330(4):1254-61. PubMed ID: 15823578
    [Abstract] [Full Text] [Related]

  • 2. Solution structure and dynamics of G1TE, a nonphosphorylated cyclic peptide inhibitor for the Grb2 SH2 domain.
    Lou YC, Lung FD, Pai MT, Tzeng SR, Wei SY, Roller PP, Cheng JW.
    Arch Biochem Biophys; 1999 Dec 15; 372(2):309-14. PubMed ID: 10600169
    [Abstract] [Full Text] [Related]

  • 3. Structural and conformational requirements for high-affinity binding to the SH2 domain of Grb2(1).
    Ettmayer P, France D, Gounarides J, Jarosinski M, Martin MS, Rondeau JM, Sabio M, Topiol S, Weidmann B, Zurini M, Bair KW.
    J Med Chem; 1999 Mar 25; 42(6):971-80. PubMed ID: 10090780
    [Abstract] [Full Text] [Related]

  • 4. Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor.
    Nioche P, Liu WQ, Broutin I, Charbonnier F, Latreille MT, Vidal M, Roques B, Garbay C, Ducruix A.
    J Mol Biol; 2002 Feb 01; 315(5):1167-77. PubMed ID: 11827484
    [Abstract] [Full Text] [Related]

  • 5. Solution structure of the C-terminal SH2 domain of the p85 alpha regulatory subunit of phosphoinositide 3-kinase.
    Siegal G, Davis B, Kristensen SM, Sankar A, Linacre J, Stein RC, Panayotou G, Waterfield MD, Driscoll PC.
    J Mol Biol; 1998 Feb 20; 276(2):461-78. PubMed ID: 9512716
    [Abstract] [Full Text] [Related]

  • 6. Surface plasmon resonance thermodynamic and kinetic analysis as a strategic tool in drug design. Distinct ways for phosphopeptides to plug into Src- and Grb2 SH2 domains.
    de Mol NJ, Dekker FJ, Broutin I, Fischer MJ, Liskamp RM.
    J Med Chem; 2005 Feb 10; 48(3):753-63. PubMed ID: 15689159
    [Abstract] [Full Text] [Related]

  • 7. Backbone dynamics of the C-terminal SH2 domain of the p85alpha subunit of phosphoinositide 3-kinase: effect of phosphotyrosine-peptide binding and characterization of slow conformational exchange processes.
    Kristensen SM, Siegal G, Sankar A, Driscoll PC.
    J Mol Biol; 2000 Jun 09; 299(3):771-88. PubMed ID: 10835283
    [Abstract] [Full Text] [Related]

  • 8. Global optimization of conformational constraint on non-phosphorylated cyclic peptide antagonists of the Grb2-SH2 domain.
    Long YQ, Lung FD, Roller PP.
    Bioorg Med Chem; 2003 Sep 01; 11(18):3929-36. PubMed ID: 12927853
    [Abstract] [Full Text] [Related]

  • 9. Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing alpha-methylphenylalanyl based phosphotyrosyl mimetics.
    Oishi S, Karki RG, Kang SU, Wang X, Worthy KM, Bindu LK, Nicklaus MC, Fisher RJ, Burke TR.
    J Med Chem; 2005 Feb 10; 48(3):764-72. PubMed ID: 15689160
    [Abstract] [Full Text] [Related]

  • 10. Solution structure of the SH2 domain of Grb2 complexed with the Shc-derived phosphotyrosine-containing peptide.
    Ogura K, Tsuchiya S, Terasawa H, Yuzawa S, Hatanaka H, Mandiyan V, Schlessinger J, Inagaki F.
    J Mol Biol; 1999 Jun 11; 289(3):439-45. PubMed ID: 10356320
    [Abstract] [Full Text] [Related]

  • 11. Evaluation of macrocyclic Grb2 SH2 domain-binding peptide mimetics prepared by ring-closing metathesis of C-terminal allylglycines with an N-terminal beta-vinyl-substituted phosphotyrosyl mimetic.
    Oishi S, Karki RG, Shi ZD, Worthy KM, Bindu L, Chertov O, Esposito D, Frank P, Gillette WK, Maderia M, Hartley J, Nicklaus MC, Barchi JJ, Fisher RJ, Burke TR.
    Bioorg Med Chem; 2005 Apr 01; 13(7):2431-8. PubMed ID: 15755645
    [Abstract] [Full Text] [Related]

  • 12. Utilization of a beta-aminophosphotyrosyl mimetic in the design and synthesis of macrocyclic Grb2 SH2 domain-binding peptides.
    Lee K, Zhang M, Liu H, Yang D, Burke TR.
    J Med Chem; 2003 Jun 19; 46(13):2621-30. PubMed ID: 12801226
    [Abstract] [Full Text] [Related]

  • 13. Potent inhibition of Grb2 SH2 domain binding by non-phosphate-containing ligands.
    Yao ZJ, King CR, Cao T, Kelley J, Milne GW, Voigt JH, Burke TR.
    J Med Chem; 1999 Jan 14; 42(1):25-35. PubMed ID: 9888830
    [Abstract] [Full Text] [Related]

  • 14. Small nonphosphorylated Grb2-SH2 domain antagonists evaluated by surface plasmon resonance technology.
    Lung FD, Chang CW, Chong MC, Liou CC, Li P, Peach ML, Nicklaus MC, Lou BS, Roller PP.
    Biopolymers; 2005 Jan 14; 80(5):628-35. PubMed ID: 15660381
    [Abstract] [Full Text] [Related]

  • 15. Structural basis for the high affinity of amino-aromatic SH2 phosphopeptide ligands.
    Rahuel J, García-Echeverría C, Furet P, Strauss A, Caravatti G, Fretz H, Schoepfer J, Gay B.
    J Mol Biol; 1998 Jun 19; 279(4):1013-22. PubMed ID: 9642078
    [Abstract] [Full Text] [Related]

  • 16. Functional preference of the constituent amino acid residues in a phage-library-based nonphosphorylated inhibitor of the Grb2-SH2 domain.
    Lung FD, Long YQ, Roller PP, King CR, Varady J, Wu XW, Wang S.
    J Pept Res; 2001 Jun 19; 57(6):447-54. PubMed ID: 11437948
    [Abstract] [Full Text] [Related]

  • 17. Nuclear magnetic resonance solution structure of the growth factor receptor-bound protein 2 Src homology 2 domain.
    Thornton KH, Mueller WT, McConnell P, Zhu G, Saltiel AR, Thanabal V.
    Biochemistry; 1996 Sep 10; 35(36):11852-64. PubMed ID: 8794768
    [Abstract] [Full Text] [Related]

  • 18. Grb2 SH2 domain-binding peptide analogs as potential anticancer agents.
    Lung FD, Tsai JY.
    Biopolymers; 2003 Sep 10; 71(2):132-40. PubMed ID: 12767115
    [Abstract] [Full Text] [Related]

  • 19.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 20. The three-dimensional solution structure of the SH2 domain from p55blk kinase.
    Metzler WJ, Leiting B, Pryor K, Mueller L, Farmer BT.
    Biochemistry; 1996 May 21; 35(20):6201-11. PubMed ID: 8639560
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 43.