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849 related items for PubMed ID: 15823578

  • 21. Structure-based design and synthesis of high affinity tripeptide ligands of the Grb2-SH2 domain.
    Furet P, Gay B, Caravatti G, García-Echeverría C, Rahuel J, Schoepfer J, Fretz H.
    J Med Chem; 1998 Aug 27; 41(18):3442-9. PubMed ID: 9719597
    [Abstract] [Full Text] [Related]

  • 22. Macrocyclization in the design of Grb2 SH2 domain-binding ligands exhibiting high potency in whole-cell systems.
    Wei CQ, Gao Y, Lee K, Guo R, Li B, Zhang M, Yang D, Burke TR.
    J Med Chem; 2003 Jan 16; 46(2):244-54. PubMed ID: 12519063
    [Abstract] [Full Text] [Related]

  • 23. Molecular and cellular analysis of Grb2 SH3 domain mutants: interaction with Sos and dynamin.
    Vidal M, Goudreau N, Cornille F, Cussac D, Gincel E, Garbay C.
    J Mol Biol; 1999 Jul 16; 290(3):717-30. PubMed ID: 10395825
    [Abstract] [Full Text] [Related]

  • 24. Utilization of 3'-carboxy-containing tyrosine derivatives as a new class of phosphotyrosyl mimetics in the preparation of novel non-phosphorylated cyclic peptide inhibitors of the Grb2-SH2 domain.
    Song YL, Tan J, Luo XM, Long YQ.
    Org Biomol Chem; 2006 Feb 21; 4(4):659-66. PubMed ID: 16467940
    [Abstract] [Full Text] [Related]

  • 25. Solution structure of Grb2 reveals extensive flexibility necessary for target recognition.
    Yuzawa S, Yokochi M, Hatanaka H, Ogura K, Kataoka M, Miura K, Mandiyan V, Schlessinger J, Inagaki F.
    J Mol Biol; 2001 Feb 23; 306(3):527-37. PubMed ID: 11178911
    [Abstract] [Full Text] [Related]

  • 26. Synthesis of a C-terminally biotinylated macrocyclic peptide mimetic exhibiting high Grb2 SH2 domain-binding affinity.
    Shi ZD, Liu H, Zhang M, Worthy KM, Bindu L, Yang D, Fisher RJ, Burke TR.
    Bioorg Med Chem; 2005 Jul 01; 13(13):4200-8. PubMed ID: 15893931
    [Abstract] [Full Text] [Related]

  • 27. Dual specificity of Src homology 2 domains for phosphotyrosine peptide ligands.
    Gay B, Furet P, García-Echeverría C, Rahuel J, Chène P, Fretz H, Schoepfer J, Caravatti G.
    Biochemistry; 1997 May 13; 36(19):5712-8. PubMed ID: 9153411
    [Abstract] [Full Text] [Related]

  • 28. Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
    Wittekind M, Mapelli C, Lee V, Goldfarb V, Friedrichs MS, Meyers CA, Mueller L.
    J Mol Biol; 1997 Apr 11; 267(4):933-52. PubMed ID: 9135122
    [Abstract] [Full Text] [Related]

  • 29. Structure of subtilosin A, a cyclic antimicrobial peptide from Bacillus subtilis with unusual sulfur to alpha-carbon cross-links: formation and reduction of alpha-thio-alpha-amino acid derivatives.
    Kawulka KE, Sprules T, Diaper CM, Whittal RM, McKay RT, Mercier P, Zuber P, Vederas JC.
    Biochemistry; 2004 Mar 30; 43(12):3385-95. PubMed ID: 15035610
    [Abstract] [Full Text] [Related]

  • 30. Macrocyclization in the design of non-phosphorus-containing Grb2 SH2 domain-binding ligands.
    Shi ZD, Wei CQ, Lee K, Liu H, Zhang M, Araki T, Roberts LR, Worthy KM, Fisher RJ, Neel BG, Kelley JA, Yang D, Burke TR.
    J Med Chem; 2004 Apr 08; 47(8):2166-9. PubMed ID: 15056012
    [Abstract] [Full Text] [Related]

  • 31. Ligand-induced strain in hydrogen bonds of the c-Src SH3 domain detected by NMR.
    Cordier F, Wang C, Grzesiek S, Nicholson LK.
    J Mol Biol; 2000 Dec 08; 304(4):497-505. PubMed ID: 11099375
    [Abstract] [Full Text] [Related]

  • 32. Interaction of the non-phosphorylated peptide G7-18NATE with Grb7-SH2 domain requires phosphate for enhanced affinity and specificity.
    Gunzburg MJ, Ambaye ND, Del Borgo MP, Pero SC, Krag DN, Wilce MC, Wilce JA.
    J Mol Recognit; 2012 Jan 08; 25(1):57-67. PubMed ID: 22213451
    [Abstract] [Full Text] [Related]

  • 33. Design and biological evaluation of linear and cyclic phosphopeptide ligands of the N-terminal SH2 domain of protein tyrosine phosphatase SHP-1.
    Imhof D, Wieligmann K, Hampel K, Nothmann D, Zoda MS, Schmidt-Arras D, Zacharias M, Böhmer FD, Reissmann S.
    J Med Chem; 2005 Mar 10; 48(5):1528-39. PubMed ID: 15743195
    [Abstract] [Full Text] [Related]

  • 34. Potentiating effect of distant sites in non-phosphorylated cyclic peptide antagonists of the Grb2-SH2 domain.
    Long YQ, Guo R, Luo JH, Yang D, Roller PP.
    Biochem Biophys Res Commun; 2003 Oct 17; 310(2):334-40. PubMed ID: 14521914
    [Abstract] [Full Text] [Related]

  • 35. Thermodynamic and structural analysis of phosphotyrosine polypeptide binding to Grb2-SH2.
    McNemar C, Snow ME, Windsor WT, Prongay A, Mui P, Zhang R, Durkin J, Le HV, Weber PC.
    Biochemistry; 1997 Aug 19; 36(33):10006-14. PubMed ID: 9254595
    [Abstract] [Full Text] [Related]

  • 36. Synthesis and utilization of chiral alpha-methylated alpha-amino acids with a carboxyalkyl side chain in the design of novel Grb2-SH2 peptide inhibitors free of phosphotyrosine.
    Long YQ, Xue T, Song YL, Liu ZL, Huang SX, Yu Q.
    J Med Chem; 2008 Oct 23; 51(20):6371-80. PubMed ID: 18821748
    [Abstract] [Full Text] [Related]

  • 37. Utilization of a common pathway for the synthesis of high affinity macrocyclic Grb2 SH2 domain-binding peptide mimetics that differ in the configuration at one ring junction.
    Shi ZD, Karki RG, Worthy KM, Bindu LK, Nicklaus MC, Fisher RJ, Burke TR.
    Chem Biodivers; 2005 Apr 23; 2(4):447-56. PubMed ID: 17191992
    [Abstract] [Full Text] [Related]

  • 38.
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    [No Abstract] [Full Text] [Related]

  • 39. Discovery of 3-aminobenzyloxycarbonyl as an N-terminal group conferring high affinity to the minimal phosphopeptide sequence recognized by the Grb2-SH2 domain.
    Furet P, Gay B, García-Echeverría C, Rahuel J, Fretz H, Schoepfer J, Caravatti G.
    J Med Chem; 1997 Oct 24; 40(22):3551-6. PubMed ID: 9357522
    [Abstract] [Full Text] [Related]

  • 40. Small peptides containing phosphotyrosine and adjacent alphaMe-phosphotyrosine or its mimetics as highly potent inhibitors of Grb2 SH2 domain.
    Liu WQ, Vidal M, Gresh N, Roques BP, Garbay C.
    J Med Chem; 1999 Sep 09; 42(18):3737-41. PubMed ID: 10479306
    [Abstract] [Full Text] [Related]

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