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Journal Abstract Search

316 related items for PubMed ID: 15826241

  • 1. The N370S (Asn370-->Ser) mutation affects the capacity of glucosylceramidase to interact with anionic phospholipid-containing membranes and saposin C.
    Salvioli R, Tatti M, Scarpa S, Moavero SM, Ciaffoni F, Felicetti F, Kaneski CR, Brady RO, Vaccaro AM.
    Biochem J; 2005 Aug 15; 390(Pt 1):95-103. PubMed ID: 15826241
    [Abstract] [Full Text] [Related]

  • 2. Interaction of saposin D with membranes: effect of anionic phospholipids and sphingolipids.
    Ciaffoni F, Tatti M, Salvioli R, Vaccaro AM.
    Biochem J; 2003 Aug 01; 373(Pt 3):785-92. PubMed ID: 12733985
    [Abstract] [Full Text] [Related]

  • 3. Direct AFM observation of saposin C-induced membrane domains in lipid bilayers: from simple to complex lipid mixtures.
    You HX, Qi X, Yu L.
    Chem Phys Lipids; 2004 Nov 01; 132(1):15-22. PubMed ID: 15530444
    [Abstract] [Full Text] [Related]

  • 4. Further studies on the reconstitution of glucosylceramidase activity by Sap C and anionic phospholipids.
    Salvioli R, Tatti M, Ciaffoni F, Vaccaro AM.
    FEBS Lett; 2000 Apr 21; 472(1):17-21. PubMed ID: 10781797
    [Abstract] [Full Text] [Related]

  • 5. Glucosylceramidase mass and subcellular localization are modulated by cholesterol in Niemann-Pick disease type C.
    Salvioli R, Scarpa S, Ciaffoni F, Tatti M, Ramoni C, Vanier MT, Vaccaro AM.
    J Biol Chem; 2004 Apr 23; 279(17):17674-80. PubMed ID: 14757764
    [Abstract] [Full Text] [Related]

  • 6. Characterization of the N370S mutant of glucocerebrosidase by hydrogen/deuterium exchange mass spectrometry.
    Tang L, Coales SJ, Morrow JA, Edmunds T, Hamuro Y.
    Chembiochem; 2012 Oct 15; 13(15):2243-50. PubMed ID: 22961873
    [Abstract] [Full Text] [Related]

  • 7. Role of pH in determining the cell-type-specific residual activity of glucocerebrosidase in type 1 Gaucher disease.
    van Weely S, van den Berg M, Barranger JA, Sa Miranda MC, Tager JM, Aerts JM.
    J Clin Invest; 1993 Mar 15; 91(3):1167-75. PubMed ID: 8450045
    [Abstract] [Full Text] [Related]

  • 8. Saposin C mutations in Gaucher disease patients resulting in lysosomal lipid accumulation, saposin C deficiency, but normal prosaposin processing and sorting.
    Vaccaro AM, Motta M, Tatti M, Scarpa S, Masuelli L, Bhat M, Vanier MT, Tylki-Szymanska A, Salvioli R.
    Hum Mol Genet; 2010 Aug 01; 19(15):2987-97. PubMed ID: 20484222
    [Abstract] [Full Text] [Related]

  • 9. Acid beta-glucosidase: intrinsic fluorescence and conformational changes induced by phospholipids and saposin C.
    Qi X, Grabowski GA.
    Biochemistry; 1998 Aug 18; 37(33):11544-54. PubMed ID: 9708990
    [Abstract] [Full Text] [Related]

  • 10. An evolutionary and structure-based docking model for glucocerebrosidase-saposin C and glucocerebrosidase-substrate interactions - relevance for Gaucher disease.
    Atrian S, López-Viñas E, Gómez-Puertas P, Chabás A, Vilageliu L, Grinberg D.
    Proteins; 2008 Feb 15; 70(3):882-91. PubMed ID: 17803231
    [Abstract] [Full Text] [Related]

  • 11. Fusogenic domain and lysines in saposin C.
    Qi X, Chu Z.
    Arch Biochem Biophys; 2004 Apr 15; 424(2):210-8. PubMed ID: 15047193
    [Abstract] [Full Text] [Related]

  • 12. Efficient one-step chromatographic purification and functional characterization of recombinant human Saposin C.
    Motta M, Tatti M, Martinelli S, Camerini S, Scarpa S, Crescenzi M, Tartaglia M, Salvioli R.
    Protein Expr Purif; 2011 Aug 15; 78(2):209-15. PubMed ID: 21463688
    [Abstract] [Full Text] [Related]

  • 13. Hydrophilic iminosugar active-site-specific chaperones increase residual glucocerebrosidase activity in fibroblasts from Gaucher patients.
    Chang HH, Asano N, Ishii S, Ichikawa Y, Fan JQ.
    FEBS J; 2006 Sep 15; 273(17):4082-92. PubMed ID: 16934036
    [Abstract] [Full Text] [Related]

  • 14. The effects of chemically synthesized saposin C on glucosylceramide-β-glucosidase.
    Yoneshige A, Muto M, Watanabe T, Hojo H, Matsuda J.
    Clin Biochem; 2015 Nov 15; 48(16-17):1177-80. PubMed ID: 26068040
    [Abstract] [Full Text] [Related]

  • 15. Dissociation of glucocerebrosidase dimer in solution by its co-factor, saposin C.
    Gruschus JM, Jiang Z, Yap TL, Hill SA, Grishaev A, Piszczek G, Sidransky E, Lee JC.
    Biochem Biophys Res Commun; 2015 Feb 20; 457(4):561-6. PubMed ID: 25600808
    [Abstract] [Full Text] [Related]

  • 16. Polyhydroxylated bicyclic isoureas and guanidines are potent glucocerebrosidase inhibitors and nanomolar enzyme activity enhancers in Gaucher cells.
    Trapero A, Alfonso I, Butters TD, Llebaria A.
    J Am Chem Soc; 2011 Apr 13; 133(14):5474-84. PubMed ID: 21413704
    [Abstract] [Full Text] [Related]

  • 17. Analyses of variant acid beta-glucosidases: effects of Gaucher disease mutations.
    Liou B, Kazimierczuk A, Zhang M, Scott CR, Hegde RS, Grabowski GA.
    J Biol Chem; 2006 Feb 17; 281(7):4242-53. PubMed ID: 16293621
    [Abstract] [Full Text] [Related]

  • 18. Structure of acid beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease.
    Lieberman RL, Wustman BA, Huertas P, Powe AC, Pine CW, Khanna R, Schlossmacher MG, Ringe D, Petsko GA.
    Nat Chem Biol; 2007 Feb 17; 3(2):101-7. PubMed ID: 17187079
    [Abstract] [Full Text] [Related]

  • 19. Functional analysis of 13 GBA mutant alleles identified in Gaucher disease patients: Pathogenic changes and "modifier" polymorphisms.
    Montfort M, Chabás A, Vilageliu L, Grinberg D.
    Hum Mutat; 2004 Jun 17; 23(6):567-75. PubMed ID: 15146461
    [Abstract] [Full Text] [Related]

  • 20. Gaucher disease due to saposin C deficiency is an inherited lysosomal disease caused by rapidly degraded mutant proteins.
    Motta M, Camerini S, Tatti M, Casella M, Torreri P, Crescenzi M, Tartaglia M, Salvioli R.
    Hum Mol Genet; 2014 Nov 01; 23(21):5814-26. PubMed ID: 24925315
    [Abstract] [Full Text] [Related]

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