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227 related items for PubMed ID: 15826493
1. Differential expression and stability of endogenous nuclear factor E2-related factor 2 (Nrf2) by natural chemopreventive compounds in HepG2 human hepatoma cells. Jeong WS, Keum YS, Chen C, Jain MR, Shen G, Kim JH, Li W, Kong AN. J Biochem Mol Biol; 2005 Mar 31; 38(2):167-76. PubMed ID: 15826493 [Abstract] [Full Text] [Related]
2. Pharmacodynamics of dietary phytochemical indoles I3C and DIM: Induction of Nrf2-mediated phase II drug metabolizing and antioxidant genes and synergism with isothiocyanates. Saw CL, Cintrón M, Wu TY, Guo Y, Huang Y, Jeong WS, Kong AN. Biopharm Drug Dispos; 2011 Jul 31; 32(5):289-300. PubMed ID: 21656528 [Abstract] [Full Text] [Related]
3. Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals. Chen C, Pung D, Leong V, Hebbar V, Shen G, Nair S, Li W, Kong AN. Free Radic Biol Med; 2004 Nov 15; 37(10):1578-90. PubMed ID: 15477009 [Abstract] [Full Text] [Related]
4. Mechanism of action of sulforaphane: inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma HepG2 cells. Keum YS, Yu S, Chang PP, Yuan X, Kim JH, Xu C, Han J, Agarwal A, Kong AN. Cancer Res; 2006 Sep 01; 66(17):8804-13. PubMed ID: 16951197 [Abstract] [Full Text] [Related]
5. Structural influence of isothiocyanates on the antioxidant response element (ARE)-mediated heme oxygenase-1 (HO-1) expression. Prawan A, Keum YS, Khor TO, Yu S, Nair S, Li W, Hu L, Kong AN. Pharm Res; 2008 Apr 01; 25(4):836-44. PubMed ID: 17657593 [Abstract] [Full Text] [Related]
6. Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress. Zhang DD, Hannink M. Mol Cell Biol; 2003 Nov 01; 23(22):8137-51. PubMed ID: 14585973 [Abstract] [Full Text] [Related]
7. Regulation of the Keap1/Nrf2 system by chemopreventive sulforaphane: implications of posttranslational modifications. Keum YS. Ann N Y Acad Sci; 2011 Jul 01; 1229():184-9. PubMed ID: 21793854 [Abstract] [Full Text] [Related]
8. Heteroaromatic 4-arylquinols are novel inducers of nuclear factor-erythroid 2-related factor 2 (Nrf2). Wong DP, Wells G, Hagen T. Eur J Pharmacol; 2010 Sep 25; 643(2-3):188-94. PubMed ID: 20599909 [Abstract] [Full Text] [Related]
9. Piceatannol induces heme oxygenase-1 expression in human mammary epithelial cells through activation of ARE-driven Nrf2 signaling. Lee HH, Park SA, Almazari I, Kim EH, Na HK, Surh YJ. Arch Biochem Biophys; 2010 Sep 01; 501(1):142-50. PubMed ID: 20558128 [Abstract] [Full Text] [Related]
10. Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2. Xu C, Yuan X, Pan Z, Shen G, Kim JH, Yu S, Khor TO, Li W, Ma J, Kong AN. Mol Cancer Ther; 2006 Aug 01; 5(8):1918-26. PubMed ID: 16928811 [Abstract] [Full Text] [Related]
11. Transcription factor Nrf2/MafK regulates rat placental glutathione S-transferase gene during hepatocarcinogenesis. Ikeda H, Nishi S, Sakai M. Biochem J; 2004 Jun 01; 380(Pt 2):515-21. PubMed ID: 14960151 [Abstract] [Full Text] [Related]
12. Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation. He CH, Gong P, Hu B, Stewart D, Choi ME, Choi AM, Alam J. J Biol Chem; 2001 Jun 15; 276(24):20858-65. PubMed ID: 11274184 [Abstract] [Full Text] [Related]
13. Nuclear factor E2-related factor 2-mediated induction of NAD(P)H:quinone oxidoreductase 1 by 3,5-dimethoxy-trans-stilbene. Park EJ, Min HY, Park HJ, Chung HJ, Ahn YH, Pyee JH, Lee SK. J Pharmacol Sci; 2011 Jun 15; 116(1):89-96. PubMed ID: 21512304 [Abstract] [Full Text] [Related]
14. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex. Zhang DD, Lo SC, Cross JV, Templeton DJ, Hannink M. Mol Cell Biol; 2004 Dec 15; 24(24):10941-53. PubMed ID: 15572695 [Abstract] [Full Text] [Related]
15. Auranofin, a gold(I)-containing antirheumatic compound, activates Keap1/Nrf2 signaling via Rac1/iNOS signal and mitogen-activated protein kinase activation. Kim NH, Oh MK, Park HJ, Kim IS. J Pharmacol Sci; 2010 Dec 15; 113(3):246-54. PubMed ID: 20647686 [Abstract] [Full Text] [Related]
16. Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3. Rojo AI, Medina-Campos ON, Rada P, Zúñiga-Toalá A, López-Gazcón A, Espada S, Pedraza-Chaverri J, Cuadrado A. Free Radic Biol Med; 2012 Jan 15; 52(2):473-87. PubMed ID: 22142471 [Abstract] [Full Text] [Related]
17. Butylated hydroxyanisole regulates ARE-mediated gene expression via Nrf2 coupled with ERK and JNK signaling pathway in HepG2 cells. Yuan X, Xu C, Pan Z, Keum YS, Kim JH, Shen G, Yu S, Oo KT, Ma J, Kong AN. Mol Carcinog; 2006 Nov 15; 45(11):841-50. PubMed ID: 16739127 [Abstract] [Full Text] [Related]
18. Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2. Eggler AL, Liu G, Pezzuto JM, van Breemen RB, Mesecar AD. Proc Natl Acad Sci U S A; 2005 Jul 19; 102(29):10070-5. PubMed ID: 16006525 [Abstract] [Full Text] [Related]
19. Involvement of Nrf2 and JNK1 in the activation of antioxidant responsive element (ARE) by chemopreventive agent phenethyl isothiocyanate (PEITC). Keum YS, Owuor ED, Kim BR, Hu R, Kong AN. Pharm Res; 2003 Sep 19; 20(9):1351-6. PubMed ID: 14567627 [Abstract] [Full Text] [Related]
20. Sulforaphane but not ascorbigen, indole-3-carbinole and ascorbic acid activates the transcription factor Nrf2 and induces phase-2 and antioxidant enzymes in human keratinocytes in culture. Wagner AE, Ernst I, Iori R, Desel C, Rimbach G. Exp Dermatol; 2010 Feb 19; 19(2):137-44. PubMed ID: 19558496 [Abstract] [Full Text] [Related] Page: [Next] [New Search]