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282 related items for PubMed ID: 15833898
21. Modulation of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) by 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives, ligands of peripheral benzodiazepine receptor (PBR). Anderson LE, Dring AM, Hamel LD, Stoner MA. Toxicol Lett; 2011 Apr 25; 202(2):148-54. PubMed ID: 21315811 [Abstract] [Full Text] [Related]
22. Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice. Saini SP, Mu Y, Gong H, Toma D, Uppal H, Ren S, Li S, Poloyac SM, Xie W. Hepatology; 2005 Mar 25; 41(3):497-505. PubMed ID: 15726644 [Abstract] [Full Text] [Related]
23. Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors. Moore LB, Maglich JM, McKee DD, Wisely B, Willson TM, Kliewer SA, Lambert MH, Moore JT. Mol Endocrinol; 2002 May 25; 16(5):977-86. PubMed ID: 11981033 [Abstract] [Full Text] [Related]
24. PXR, CAR and drug metabolism. Willson TM, Kliewer SA. Nat Rev Drug Discov; 2002 Apr 25; 1(4):259-66. PubMed ID: 12120277 [Abstract] [Full Text] [Related]
25. Dose-dependent difference of nuclear receptors involved in murine liver hypertrophy by piperonyl butoxide. Sakamoto Y, Yoshida M, Tamura K, Takahashi M, Kodama Y, Inoue K. J Toxicol Sci; 2015 Dec 25; 40(6):787-96. PubMed ID: 26558459 [Abstract] [Full Text] [Related]
26. Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor. Goodwin B, Moore LB, Stoltz CM, McKee DD, Kliewer SA. Mol Pharmacol; 2001 Sep 25; 60(3):427-31. PubMed ID: 11502872 [Abstract] [Full Text] [Related]
27. Identification of three novel natural product compounds that activate PXR and CAR and inhibit inflammation. Kittayaruksakul S, Zhao W, Xu M, Ren S, Lu J, Wang J, Downes M, Evans RM, Venkataramanan R, Chatsudthipong V, Xie W. Pharm Res; 2013 Sep 25; 30(9):2199-208. PubMed ID: 23896737 [Abstract] [Full Text] [Related]
29. The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor. Wang H, Li H, Moore LB, Johnson MD, Maglich JM, Goodwin B, Ittoop OR, Wisely B, Creech K, Parks DJ, Collins JL, Willson TM, Kalpana GV, Venkatesh M, Xie W, Cho SY, Roboz J, Redinbo M, Moore JT, Mani S. Mol Endocrinol; 2008 Apr 25; 22(4):838-57. PubMed ID: 18096694 [Abstract] [Full Text] [Related]
30. Expression and transcriptional activities of nuclear receptors involved in regulation of drug-metabolizing enzymes are not altered by colchicine: focus on PXR, CAR, and GR in primary human hepatocytes. Dvorák Z, Maurel P, Vilarem MJ, Ulrichová J, Modrianský M. Cell Biol Toxicol; 2007 Mar 25; 23(2):63-73. PubMed ID: 16964586 [Abstract] [Full Text] [Related]
31. Activation of human CYP2C9 promoter and regulation by CAR and PXR in mouse liver. Al-Dosari MS, Knapp JE, Liu D. Mol Pharm; 2006 Mar 25; 3(3):322-8. PubMed ID: 16749864 [Abstract] [Full Text] [Related]
32. The xenobiotic-sensing nuclear receptors pregnane X receptor, constitutive androstane receptor, and orphan nuclear receptor hepatocyte nuclear factor 4alpha in the regulation of human steroid-/bile acid-sulfotransferase. Echchgadda I, Song CS, Oh T, Ahmed M, De La Cruz IJ, Chatterjee B. Mol Endocrinol; 2007 Sep 25; 21(9):2099-111. PubMed ID: 17595319 [Abstract] [Full Text] [Related]
33. Toxaphene-induced mouse liver tumorigenesis is mediated by the constitutive androstane receptor. Wang Z, Li X, Wu Q, Lamb JC, Klaunig JE. J Appl Toxicol; 2017 Aug 25; 37(8):967-975. PubMed ID: 28218408 [Abstract] [Full Text] [Related]
34. In vivo and mechanistic evidence of nuclear receptor CAR induction by artemisinin. Simonsson US, Lindell M, Raffalli-Mathieu F, Lannerbro A, Honkakoski P, Lang MA. Eur J Clin Invest; 2006 Sep 25; 36(9):647-53. PubMed ID: 16919048 [Abstract] [Full Text] [Related]
36. Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity. Guo GL, Lambert G, Negishi M, Ward JM, Brewer HB, Kliewer SA, Gonzalez FJ, Sinal CJ. J Biol Chem; 2003 Nov 14; 278(46):45062-71. PubMed ID: 12923173 [Abstract] [Full Text] [Related]
37. The roles of co-chaperone CCRP/DNAJC7 in Cyp2b10 gene activation and steatosis development in mouse livers. Ohno M, Kanayama T, Moore R, Ray M, Negishi M. PLoS One; 2014 Nov 14; 9(12):e115663. PubMed ID: 25542016 [Abstract] [Full Text] [Related]
38. Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response. Beigneux AP, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. Biochem Biophys Res Commun; 2002 Apr 26; 293(1):145-9. PubMed ID: 12054576 [Abstract] [Full Text] [Related]
39. Rat PXR reporter-gene activity correlates with the induction of CYP3A in rat precision-cut liver slices. Cui X, Thomas A, Montgomery D, Gu C, Morrison RA, White RE, Cheng KC. Comb Chem High Throughput Screen; 2005 Jun 26; 8(4):341-6. PubMed ID: 16101010 [Abstract] [Full Text] [Related]
40. Ligand dependent hepatic gene expression profiles of nuclear receptors CAR and PXR. Tojima H, Kakizaki S, Yamazaki Y, Takizawa D, Horiguchi N, Sato K, Mori M. Toxicol Lett; 2012 Aug 03; 212(3):288-97. PubMed ID: 22698814 [Abstract] [Full Text] [Related] Page: [Previous] [Next] [New Search]