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990 related items for PubMed ID: 15851026

  • 21. Platelet-derived growth factor-induced p42/44 mitogen-activated protein kinase activation and cellular growth is mediated by reactive oxygen species in the absence of TSC2/tuberin.
    Finlay GA, Thannickal VJ, Fanburg BL, Kwiatkowski DJ.
    Cancer Res; 2005 Dec 01; 65(23):10881-90. PubMed ID: 16322235
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  • 22. Frequent [corrected] hyperphosphorylation of ribosomal protein S6 [corrected] in lymphangioleiomyomatosis-associated angiomyolipomas.
    Robb VA, Astrinidis A, Henske EP.
    Mod Pathol; 2006 Jun 01; 19(6):839-46. PubMed ID: 16575396
    [Abstract] [Full Text] [Related]

  • 23. Activation of protein synthesis in cardiomyocytes by the hypertrophic agent phenylephrine requires the activation of ERK and involves phosphorylation of tuberous sclerosis complex 2 (TSC2).
    Rolfe M, McLeod LE, Pratt PF, Proud CG.
    Biochem J; 2005 Jun 15; 388(Pt 3):973-84. PubMed ID: 15757502
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  • 24. Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity.
    Li Y, Inoki K, Guan KL.
    Mol Cell Biol; 2004 Sep 15; 24(18):7965-75. PubMed ID: 15340059
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  • 25. Loss of Tsc1 or Tsc2 induces vascular endothelial growth factor production through mammalian target of rapamycin.
    El-Hashemite N, Walker V, Zhang H, Kwiatkowski DJ.
    Cancer Res; 2003 Sep 01; 63(17):5173-7. PubMed ID: 14500340
    [Abstract] [Full Text] [Related]

  • 26. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling.
    Inoki K, Li Y, Zhu T, Wu J, Guan KL.
    Nat Cell Biol; 2002 Sep 01; 4(9):648-57. PubMed ID: 12172553
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  • 27. Rheb binds and regulates the mTOR kinase.
    Long X, Lin Y, Ortiz-Vega S, Yonezawa K, Avruch J.
    Curr Biol; 2005 Apr 26; 15(8):702-13. PubMed ID: 15854902
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  • 30. Nucleocytoplasmic localization of p70 S6K1, but not of its isoforms p85 and p31, is regulated by TSC2/mTOR.
    Rosner M, Hengstschläger M.
    Oncogene; 2011 Nov 03; 30(44):4509-22. PubMed ID: 21602892
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  • 31. A reliable cell-based assay for testing unclassified TSC2 gene variants.
    Coevoets R, Arican S, Hoogeveen-Westerveld M, Simons E, van den Ouweland A, Halley D, Nellist M.
    Eur J Hum Genet; 2009 Mar 03; 17(3):301-10. PubMed ID: 18854862
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  • 32. Aberrant beta-catenin signaling in tuberous sclerosis.
    Mak BC, Kenerson HL, Aicher LD, Barnes EA, Yeung RS.
    Am J Pathol; 2005 Jul 03; 167(1):107-16. PubMed ID: 15972957
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  • 33. Role of the Rap1 GTPase in astrocyte growth regulation.
    Apicelli AJ, Uhlmann EJ, Baldwin RL, Ding H, Nagy A, Guha A, Gutmann DH.
    Glia; 2003 May 03; 42(3):225-34. PubMed ID: 12673829
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  • 34. Mutation and polymorphism analysis of TSC1 and TSC2 genes in Indian patients with tuberous sclerosis complex.
    Ali M, Girimaji SC, Markandaya M, Shukla AK, Sacchidanand S, Kumar A.
    Acta Neurol Scand; 2005 Jan 03; 111(1):54-63. PubMed ID: 15595939
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  • 35. Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR.
    Zhang H, Cicchetti G, Onda H, Koon HB, Asrican K, Bajraszewski N, Vazquez F, Carpenter CL, Kwiatkowski DJ.
    J Clin Invest; 2003 Oct 03; 112(8):1223-33. PubMed ID: 14561707
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  • 37. Tuberous sclerosis-2 tumor suppressor modulates ERK and B-Raf activity in transformed renal epithelial cells.
    Yoon HS, Ramachandiran S, Chacko MA, Monks TJ, Lau SS.
    Am J Physiol Renal Physiol; 2004 Feb 03; 286(2):F417-24. PubMed ID: 14612383
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  • 38. The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3.
    Li Y, Inoki K, Vacratsis P, Guan KL.
    J Biol Chem; 2003 Apr 18; 278(16):13663-71. PubMed ID: 12582162
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  • 39. Functional characterization of the TSC2 c.3598C>T (p.R1200W) missense mutation that co-segregates with tuberous sclerosis complex in mildly affected kindreds.
    Wentink M, Nellist M, Hoogeveen-Westerveld M, Zonnenberg B, van der Kolk D, van Essen T, Park SM, Woods G, Cohn-Hokke P, Brussel W, Smeets E, Brooks A, Halley D, van den Ouweland A, Maat-Kievit A.
    Clin Genet; 2012 May 18; 81(5):453-61. PubMed ID: 21332470
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  • 40. Phosphorylation of tuberin as a novel mechanism for somatic inactivation of the tuberous sclerosis complex proteins in brain lesions.
    Han S, Santos TM, Puga A, Roy J, Thiele EA, McCollin M, Stemmer-Rachamimov A, Ramesh V.
    Cancer Res; 2004 Feb 01; 64(3):812-6. PubMed ID: 14871804
    [Abstract] [Full Text] [Related]

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