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Journal Abstract Search


234 related items for PubMed ID: 15853709

  • 1. The therapeutic potential of inhibitors of dipeptidyl peptidase IV (DPP IV) and related proline-specific dipeptidyl aminopeptidases.
    Augustyns K, Van der Veken P, Senten K, Haemers A.
    Curr Med Chem; 2005; 12(8):971-98. PubMed ID: 15853709
    [Abstract] [Full Text] [Related]

  • 2. Catalytic properties and inhibition of proline-specific dipeptidyl peptidases II, IV and VII.
    Leiting B, Pryor KD, Wu JK, Marsilio F, Patel RA, Craik CS, Ellman JA, Cummings RT, Thornberry NA.
    Biochem J; 2003 Apr 15; 371(Pt 2):525-32. PubMed ID: 12529175
    [Abstract] [Full Text] [Related]

  • 3. Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9.
    Lankas GR, Leiting B, Roy RS, Eiermann GJ, Beconi MG, Biftu T, Chan CC, Edmondson S, Feeney WP, He H, Ippolito DE, Kim D, Lyons KA, Ok HO, Patel RA, Petrov AN, Pryor KA, Qian X, Reigle L, Woods A, Wu JK, Zaller D, Zhang X, Zhu L, Weber AE, Thornberry NA.
    Diabetes; 2005 Oct 15; 54(10):2988-94. PubMed ID: 16186403
    [Abstract] [Full Text] [Related]

  • 4. Current advances and therapeutic potential of agents targeting dipeptidyl peptidases-IV, -II, 8/9 and fibroblast activation protein.
    Chen SJ, Jiaang WT.
    Curr Top Med Chem; 2011 Oct 15; 11(12):1447-63. PubMed ID: 21510839
    [Abstract] [Full Text] [Related]

  • 5. The unique properties of dipeptidyl-peptidase IV (DPP IV / CD26) and the therapeutic potential of DPP IV inhibitors.
    Augustyns K, Bal G, Thonus G, Belyaev A, Zhang XM, Bollaert W, Lambeir AM, Durinx C, Goossens F, Haemers A.
    Curr Med Chem; 1999 Apr 15; 6(4):311-27. PubMed ID: 10101215
    [Abstract] [Full Text] [Related]

  • 6. The structural comparison of the bacterial PepX and human DPP-IV reveals sites for the design of inhibitors of PepX activity.
    Rigolet P, Xi XG, Rety S, Chich JF.
    FEBS J; 2005 Apr 15; 272(8):2050-9. PubMed ID: 15819895
    [Abstract] [Full Text] [Related]

  • 7. Hydrolysis and transport of proline-containing peptides in renal brush-border membrane vesicles from dipeptidyl peptidase IV-positive and dipeptidyl peptidase IV-negative rat strains.
    Tiruppathi C, Miyamoto Y, Ganapathy V, Roesel RA, Whitford GM, Leibach FH.
    J Biol Chem; 1990 Jan 25; 265(3):1476-83. PubMed ID: 1967253
    [Abstract] [Full Text] [Related]

  • 8. Rapid parallel synthesis of dipeptide diphenyl phosphonate esters as inhibitors of dipeptidyl peptidases.
    Senten K, Daniëls L, Van der Veken P, De Meester I, Lambeir AM, Scharpé S, Haemers A, Augustyns K.
    J Comb Chem; 2003 Jan 25; 5(3):336-44. PubMed ID: 12739951
    [Abstract] [Full Text] [Related]

  • 9. Dipeptidyl peptidase 8/9-like activity in human leukocytes.
    Maes MB, Dubois V, Brandt I, Lambeir AM, Van der Veken P, Augustyns K, Cheng JD, Chen X, Scharpé S, De Meester I.
    J Leukoc Biol; 2007 May 25; 81(5):1252-7. PubMed ID: 17287297
    [Abstract] [Full Text] [Related]

  • 10. Identification of serine 624, aspartic acid 702, and histidine 734 as the catalytic triad residues of mouse dipeptidyl-peptidase IV (CD26). A member of a novel family of nonclassical serine hydrolases.
    David F, Bernard AM, Pierres M, Marguet D.
    J Biol Chem; 1993 Aug 15; 268(23):17247-52. PubMed ID: 8102366
    [Abstract] [Full Text] [Related]

  • 11. Type 2 diabetes--therapy with dipeptidyl peptidase IV inhibitors.
    Demuth HU, McIntosh CH, Pederson RA.
    Biochim Biophys Acta; 2005 Aug 01; 1751(1):33-44. PubMed ID: 15978877
    [Abstract] [Full Text] [Related]

  • 12. Prolyl peptidases related to dipeptidyl peptidase IV: potential of specific inhibitors in drug discovery.
    Van der Veken P, Haemers A, Augustyns K.
    Curr Top Med Chem; 2007 Aug 01; 7(6):621-35. PubMed ID: 17352682
    [Abstract] [Full Text] [Related]

  • 13. Dipeptidyl peptidase IV: development, design, synthesis and biological evaluation of inhibitors.
    Borloo M, De Meester I.
    Verh K Acad Geneeskd Belg; 1994 Aug 01; 56(1):57-88. PubMed ID: 7911611
    [Abstract] [Full Text] [Related]

  • 14. Fluoro-olefins as peptidomimetic inhibitors of dipeptidyl peptidases.
    Van der Veken P, Senten K, Kertèsz I, De Meester I, Lambeir AM, Maes MB, Scharpé S, Haemers A, Augustyns K.
    J Med Chem; 2005 Mar 24; 48(6):1768-80. PubMed ID: 15771423
    [Abstract] [Full Text] [Related]

  • 15. Inhibitor selectivity in the clinical application of dipeptidyl peptidase-4 inhibition.
    Kirby M, Yu DM, O'Connor S, Gorrell MD.
    Clin Sci (Lond); 2009 Sep 28; 118(1):31-41. PubMed ID: 19780719
    [Abstract] [Full Text] [Related]

  • 16. Evidence for a role of dipeptidyl peptidase IV in fibronectin-mediated interactions of hepatocytes with extracellular matrix.
    Piazza GA, Callanan HM, Mowery J, Hixson DC.
    Biochem J; 1989 Aug 15; 262(1):327-34. PubMed ID: 2573346
    [Abstract] [Full Text] [Related]

  • 17. Development of potent and selective dipeptidyl peptidase II inhibitors.
    Senten K, Van der Veken P, Bal G, De Meester I, Lambeir AM, Scharpé S, Bauvois B, Haemers A, Augustyns K.
    Bioorg Med Chem Lett; 2002 Oct 21; 12(20):2825-8. PubMed ID: 12270155
    [Abstract] [Full Text] [Related]

  • 18. Molecular cloning and biochemical characterization of Xaa-Pro dipeptidyl-peptidase from Streptococcus mutans and its inhibition by anti-human DPP IV drugs.
    De A, Lupidi G, Petrelli D, Vitali LA.
    FEMS Microbiol Lett; 2016 May 21; 363(9):. PubMed ID: 27010012
    [Abstract] [Full Text] [Related]

  • 19. 4-Substituted boro-proline dipeptides: synthesis, characterization, and dipeptidyl peptidase IV, 8, and 9 activities.
    Wu W, Liu Y, Milo LJ, Shu Y, Zhao P, Li Y, Woznica I, Yu G, Sanford DG, Zhou Y, Poplawski SE, Connolly BA, Sudmeier JL, Bachovchin WW, Lai JH.
    Bioorg Med Chem Lett; 2012 Sep 01; 22(17):5536-40. PubMed ID: 22853995
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl}-pyrrolidine-2-carbonitrile).
    Brandt I, Joossens J, Chen X, Maes MB, Scharpé S, De Meester I, Lambeir AM.
    Biochem Pharmacol; 2005 Jul 01; 70(1):134-43. PubMed ID: 15907807
    [Abstract] [Full Text] [Related]


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