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318 related items for PubMed ID: 15855637

  • 1. Absence of proteinase-activated receptor-1 signaling affords protection from bleomycin-induced lung inflammation and fibrosis.
    Howell DC, Johns RH, Lasky JA, Shan B, Scotton CJ, Laurent GJ, Chambers RC.
    Am J Pathol; 2005 May; 166(5):1353-65. PubMed ID: 15855637
    [Abstract] [Full Text] [Related]

  • 2. Direct thrombin inhibition reduces lung collagen, accumulation, and connective tissue growth factor mRNA levels in bleomycin-induced pulmonary fibrosis.
    Howell DC, Goldsack NR, Marshall RP, McAnulty RJ, Starke R, Purdy G, Laurent GJ, Chambers RC.
    Am J Pathol; 2001 Oct; 159(4):1383-95. PubMed ID: 11583966
    [Abstract] [Full Text] [Related]

  • 3. The role of the receptor for advanced glycation end-products in lung fibrosis.
    He M, Kubo H, Ishizawa K, Hegab AE, Yamamoto Y, Yamamoto H, Yamaya M.
    Am J Physiol Lung Cell Mol Physiol; 2007 Dec; 293(6):L1427-36. PubMed ID: 17951314
    [Abstract] [Full Text] [Related]

  • 4. Geniposide ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting TGF-β/Smad and p38MAPK signaling pathways.
    Yin JB, Wang YX, Fan SS, Shang WB, Zhu YS, Peng XR, Zou C, Zhang X.
    PLoS One; 2024 Dec; 19(9):e0309833. PubMed ID: 39240867
    [Abstract] [Full Text] [Related]

  • 5. TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment.
    Degryse AL, Tanjore H, Xu XC, Polosukhin VV, Jones BR, Boomershine CS, Ortiz C, Sherrill TP, McMahon FB, Gleaves LA, Blackwell TS, Lawson WE.
    Am J Physiol Lung Cell Mol Physiol; 2011 Jun; 300(6):L887-97. PubMed ID: 21441353
    [Abstract] [Full Text] [Related]

  • 6. Role of thrombin and its major cellular receptor, protease-activated receptor-1, in pulmonary fibrosis.
    Howell DC, Laurent GJ, Chambers RC.
    Biochem Soc Trans; 2002 Apr; 30(2):211-6. PubMed ID: 12023853
    [Abstract] [Full Text] [Related]

  • 7. Pulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis.
    Mercer PF, Johns RH, Scotton CJ, Krupiczojc MA, Königshoff M, Howell DC, McAnulty RJ, Das A, Thorley AJ, Tetley TD, Eickelberg O, Chambers RC.
    Am J Respir Crit Care Med; 2009 Mar 01; 179(5):414-25. PubMed ID: 19060230
    [Abstract] [Full Text] [Related]

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  • 9. Protease-activated receptor (PAR)-2 is required for PAR-1 signalling in pulmonary fibrosis.
    Lin C, von der Thüsen J, Daalhuisen J, ten Brink M, Crestani B, van der Poll T, Borensztajn K, Spek CA.
    J Cell Mol Med; 2015 Jun 01; 19(6):1346-56. PubMed ID: 25689283
    [Abstract] [Full Text] [Related]

  • 10. Connective tissue growth factor mRNA expression is upregulated in bleomycin-induced lung fibrosis.
    Lasky JA, Ortiz LA, Tonthat B, Hoyle GW, Corti M, Athas G, Lungarella G, Brody A, Friedman M.
    Am J Physiol; 1998 Aug 01; 275(2):L365-71. PubMed ID: 9700098
    [Abstract] [Full Text] [Related]

  • 11. [Effects of andrographolide on the concentration of cytokines in BALF and the expressions of type I and III collagen mRNA in lung tissue in bleomycin-induced rat pulmonary fibrosis].
    Zhu HL, Huang CL, Wang WJ, Zhan XQ, Fan XM.
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2011 Jul 01; 27(7):725-9. PubMed ID: 21722520
    [Abstract] [Full Text] [Related]

  • 12. Uridine supplementation exerts anti-inflammatory and anti-fibrotic effects in an animal model of pulmonary fibrosis.
    Cicko S, Grimm M, Ayata K, Beckert J, Meyer A, Hossfeld M, Zissel G, Idzko M, Müller T.
    Respir Res; 2015 Sep 15; 16(1):105. PubMed ID: 26369416
    [Abstract] [Full Text] [Related]

  • 13. A prostacyclin analogue, iloprost, protects from bleomycin-induced pulmonary fibrosis in mice.
    Zhu Y, Liu Y, Zhou W, Xiang R, Jiang L, Huang K, Xiao Y, Guo Z, Gao J.
    Respir Res; 2010 Mar 20; 11(1):34. PubMed ID: 20302663
    [Abstract] [Full Text] [Related]

  • 14. Effect of pravastatin on bleomycin-induced acute lung injury and pulmonary fibrosis.
    Kim JW, Rhee CK, Kim TJ, Kim YH, Lee SH, Yoon HK, Kim SC, Lee SY, Kwon SS, Kim KH, Kim YK.
    Clin Exp Pharmacol Physiol; 2010 Nov 20; 37(11):1055-63. PubMed ID: 20659133
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  • 16. Attenuation of lung inflammation and fibrosis in CD69-deficient mice after intratracheal bleomycin.
    Yamauchi K, Kasuya Y, Kuroda F, Tanaka K, Tsuyusaki J, Ishizaki S, Matsunaga H, Iwamura C, Nakayama T, Tatsumi K.
    Respir Res; 2011 Oct 05; 12(1):131. PubMed ID: 21970554
    [Abstract] [Full Text] [Related]

  • 17. Megakaryoblastic leukemia-1 is required for the development of bleomycin-induced pulmonary fibrosis.
    Bernau K, Ngam C, Torr EE, Acton B, Kach J, Dulin NO, Sandbo N.
    Respir Res; 2015 Mar 27; 16(1):45. PubMed ID: 25885656
    [Abstract] [Full Text] [Related]

  • 18. Roles of high-mobility group box 1 and thrombin in murine pulmonary fibrosis and the therapeutic potential of thrombomodulin.
    Kida T, Seno T, Nagahara H, Inoue T, Nakabayashi A, Kukida Y, Fujioka K, Fujii W, Wada M, Kohno M, Kawahito Y.
    Am J Physiol Lung Cell Mol Physiol; 2018 Mar 01; 314(3):L473-L483. PubMed ID: 29212801
    [Abstract] [Full Text] [Related]

  • 19. Thrombin is a potent inducer of connective tissue growth factor production via proteolytic activation of protease-activated receptor-1.
    Chambers RC, Leoni P, Blanc-Brude OP, Wembridge DE, Laurent GJ.
    J Biol Chem; 2000 Nov 10; 275(45):35584-91. PubMed ID: 10952976
    [Abstract] [Full Text] [Related]

  • 20. Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagen.
    Ponticos M, Holmes AM, Shi-wen X, Leoni P, Khan K, Rajkumar VS, Hoyles RK, Bou-Gharios G, Black CM, Denton CP, Abraham DJ, Leask A, Lindahl GE.
    Arthritis Rheum; 2009 Jul 10; 60(7):2142-55. PubMed ID: 19565505
    [Abstract] [Full Text] [Related]


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