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Journal Abstract Search

307 related items for PubMed ID: 15869837

  • 21. Endocrine disruptors induce cytochrome P450 by affecting transcriptional regulation via pregnane X receptor.
    Mikamo E, Harada S, Nishikawa J, Nishihara T.
    Toxicol Appl Pharmacol; 2003 Nov 15; 193(1):66-72. PubMed ID: 14613717
    [Abstract] [Full Text] [Related]

  • 22. Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways.
    Li L, Stanton JD, Tolson AH, Luo Y, Wang H.
    Pharm Res; 2009 Apr 15; 26(4):872-82. PubMed ID: 19034627
    [Abstract] [Full Text] [Related]

  • 23. Regulation of drug transporter gene expression by nuclear receptors.
    Staudinger JL, Madan A, Carol KM, Parkinson A.
    Drug Metab Dispos; 2003 May 15; 31(5):523-7. PubMed ID: 12695338
    [Abstract] [Full Text] [Related]

  • 24. Expression of PXR, CYP3A and MDR1 genes in liver of zebrafish.
    Bresolin T, de Freitas Rebelo M, Celso Dias Bainy A.
    Comp Biochem Physiol C Toxicol Pharmacol; 2005 May 15; 140(3-4):403-7. PubMed ID: 15914091
    [Abstract] [Full Text] [Related]

  • 25. Decreased PXR and CAR inhibit transporter and CYP mRNA Levels in the liver and intestine of mice with collagen-induced arthritis.
    Kawase A, Yoshida I, Tsunokuni Y, Iwaki M.
    Xenobiotica; 2007 Apr 15; 37(4):366-74. PubMed ID: 17455111
    [Abstract] [Full Text] [Related]

  • 26. CYP3A induction by liver x receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor.
    Shenoy SD, Spencer TA, Mercer-Haines NA, Alipour M, Gargano MD, Runge-Morris M, Kocarek TA.
    Drug Metab Dispos; 2004 Jan 15; 32(1):66-71. PubMed ID: 14709622
    [Abstract] [Full Text] [Related]

  • 27. Effects of atorvastatin metabolites on induction of drug-metabolizing enzymes and membrane transporters through human pregnane X receptor.
    Hoffart E, Ghebreghiorghis L, Nussler AK, Thasler WE, Weiss TS, Schwab M, Burk O.
    Br J Pharmacol; 2012 Mar 15; 165(5):1595-608. PubMed ID: 21913896
    [Abstract] [Full Text] [Related]

  • 28. Pregnane X receptor: molecular basis for species differences in CYP3A induction by xenobiotics.
    LeCluyse EL.
    Chem Biol Interact; 2001 May 16; 134(3):283-9. PubMed ID: 11336976
    [Abstract] [Full Text] [Related]

  • 29. Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells.
    Martin P, Riley R, Back DJ, Owen A.
    Br J Pharmacol; 2008 Feb 16; 153(4):805-19. PubMed ID: 18037906
    [Abstract] [Full Text] [Related]

  • 30. Downregulation of mdr1a expression in the brain and liver during CNS inflammation alters the in vivo disposition of digoxin.
    Goralski KB, Hartmann G, Piquette-Miller M, Renton KW.
    Br J Pharmacol; 2003 May 16; 139(1):35-48. PubMed ID: 12746221
    [Abstract] [Full Text] [Related]

  • 31. Expression of cytochromes P450 3A in mouse lung: effects of dexamethasone and pregnenolone 16alpha-carbonitrile.
    Haag M, Fautrel A, Guillouzo A, Frossard N, Pons F.
    Arch Toxicol; 2003 Mar 16; 77(3):145-9. PubMed ID: 12632254
    [Abstract] [Full Text] [Related]

  • 32. Enhanced acetaminophen toxicity by activation of the pregnane X receptor.
    Guo GL, Moffit JS, Nicol CJ, Ward JM, Aleksunes LA, Slitt AL, Kliewer SA, Manautou JE, Gonzalez FJ.
    Toxicol Sci; 2004 Dec 16; 82(2):374-80. PubMed ID: 15456926
    [Abstract] [Full Text] [Related]

  • 33. CAR and PXR expression and inducibility of CYP2B and CYP3A activities in rat and rabbit lungs.
    Chirulli V, Longo V, Marini S, Mazzaccaro A, Fiorio R, Gervasi PG.
    Life Sci; 2005 Apr 15; 76(22):2535-46. PubMed ID: 15769478
    [Abstract] [Full Text] [Related]

  • 34. Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response.
    Wei P, Zhang J, Dowhan DH, Han Y, Moore DD.
    Pharmacogenomics J; 2002 Apr 15; 2(2):117-26. PubMed ID: 12049174
    [Abstract] [Full Text] [Related]

  • 35. Reactive oxygen species are involved in lipopolysaccharide-induced intrauterine growth restriction and skeletal development retardation in mice.
    Xu DX, Chen YH, Zhao L, Wang H, Wei W.
    Am J Obstet Gynecol; 2006 Dec 15; 195(6):1707-14. PubMed ID: 16769026
    [Abstract] [Full Text] [Related]

  • 36. The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes.
    Song X, Xie M, Zhang H, Li Y, Sachdeva K, Yan B.
    Drug Metab Dispos; 2004 Jan 15; 32(1):35-42. PubMed ID: 14709618
    [Abstract] [Full Text] [Related]

  • 37. A human immunodeficiency virus protease inhibitor is a novel functional inhibitor of human pregnane X receptor.
    Healan-Greenberg C, Waring JF, Kempf DJ, Blomme EA, Tirona RG, Kim RB.
    Drug Metab Dispos; 2008 Mar 15; 36(3):500-7. PubMed ID: 18096673
    [Abstract] [Full Text] [Related]

  • 38. Expression of CYP3A in chronic ethanol-fed mice is mediated by endogenous pregnane X receptor ligands formed by enhanced cholesterol metabolism.
    Je YT, Sim WC, Kim DG, Jung BH, Shin HS, Lee BH.
    Arch Toxicol; 2015 Apr 15; 89(4):579-89. PubMed ID: 24853400
    [Abstract] [Full Text] [Related]

  • 39. Regulation of hepatic abcb4 and cyp3a65 gene expression and multidrug/multixenobiotic resistance (MDR/MXR) functional activity in the model teleost, Danio rerio (zebrafish).
    Jackson JS, Kennedy CJ.
    Comp Biochem Physiol C Toxicol Pharmacol; 2017 Oct 15; 200():34-41. PubMed ID: 28624525
    [Abstract] [Full Text] [Related]

  • 40. Repression of PXR-mediated induction of hepatic CYP3A gene expression by protein kinase C.
    Ding X, Staudinger JL.
    Biochem Pharmacol; 2005 Mar 01; 69(5):867-73. PubMed ID: 15710363
    [Abstract] [Full Text] [Related]

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