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Journal Abstract Search

1771 related items for PubMed ID: 15870086

  • 1. Antitumoral actions of the anti-obesity drug orlistat (XenicalTM) in breast cancer cells: blockade of cell cycle progression, promotion of apoptotic cell death and PEA3-mediated transcriptional repression of Her2/neu (erbB-2) oncogene.
    Menendez JA, Vellon L, Lupu R.
    Ann Oncol; 2005 Aug; 16(8):1253-67. PubMed ID: 15870086
    [Abstract] [Full Text] [Related]

  • 2. Oleic acid, the main monounsaturated fatty acid of olive oil, suppresses Her-2/neu (erbB-2) expression and synergistically enhances the growth inhibitory effects of trastuzumab (Herceptin) in breast cancer cells with Her-2/neu oncogene amplification.
    Menendez JA, Vellon L, Colomer R, Lupu R.
    Ann Oncol; 2005 Mar; 16(3):359-71. PubMed ID: 15642702
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells.
    Menendez JA, Vellon L, Mehmi I, Oza BP, Ropero S, Colomer R, Lupu R.
    Proc Natl Acad Sci U S A; 2004 Jul 20; 101(29):10715-20. PubMed ID: 15235125
    [Abstract] [Full Text] [Related]

  • 4. DNA topoisomerase IIalpha (TOP2A) inhibitors up-regulate fatty acid synthase gene expression in SK-Br3 breast cancer cells: in vitro evidence for a 'functional amplicon' involving FAS, Her-2/neu and TOP2A genes.
    Menendez JA, Vellon L, Lupu R.
    Int J Mol Med; 2006 Dec 20; 18(6):1081-7. PubMed ID: 17089011
    [Abstract] [Full Text] [Related]

  • 5. Pharmacological and small interference RNA-mediated inhibition of breast cancer-associated fatty acid synthase (oncogenic antigen-519) synergistically enhances Taxol (paclitaxel)-induced cytotoxicity.
    Menendez JA, Vellon L, Colomer R, Lupu R.
    Int J Cancer; 2005 May 20; 115(1):19-35. PubMed ID: 15657900
    [Abstract] [Full Text] [Related]

  • 6. Targeting fatty acid synthase-driven lipid rafts: a novel strategy to overcome trastuzumab resistance in breast cancer cells.
    Menendez JA, Vellon L, Lupu R.
    Med Hypotheses; 2005 May 20; 64(5):997-1001. PubMed ID: 15780499
    [Abstract] [Full Text] [Related]

  • 7. HER2 (erbB-2)-targeted effects of the omega-3 polyunsaturated fatty acid, alpha-linolenic acid (ALA; 18:3n-3), in breast cancer cells: the "fat features" of the "Mediterranean diet" as an "anti-HER2 cocktail".
    Menéndez JA, Vázquez-Martín A, Ropero S, Colomer R, Lupu R.
    Clin Transl Oncol; 2006 Nov 20; 8(11):812-20. PubMed ID: 17134970
    [Abstract] [Full Text] [Related]

  • 8. Pharmacological blockade of fatty acid synthase (FASN) reverses acquired autoresistance to trastuzumab (Herceptin by transcriptionally inhibiting 'HER2 super-expression' occurring in high-dose trastuzumab-conditioned SKBR3/Tzb100 breast cancer cells.
    Vazquez-Martin A, Colomer R, Brunet J, Menendez JA.
    Int J Oncol; 2007 Oct 20; 31(4):769-76. PubMed ID: 17786307
    [Abstract] [Full Text] [Related]

  • 9. Mediterranean dietary traditions for the molecular treatment of human cancer: anti-oncogenic actions of the main olive oil's monounsaturated fatty acid oleic acid (18:1n-9).
    Menendez JA, Lupu R.
    Curr Pharm Biotechnol; 2006 Dec 20; 7(6):495-502. PubMed ID: 17168666
    [Abstract] [Full Text] [Related]

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  • 12. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
    Menendez JA, Mehmi I, Atlas E, Colomer R, Lupu R.
    Int J Oncol; 2004 Mar 20; 24(3):591-608. PubMed ID: 14767544
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  • 14. Pharmacological inhibition of fatty acid synthase (FAS): a novel therapeutic approach for breast cancer chemoprevention through its ability to suppress Her-2/neu (erbB-2) oncogene-induced malignant transformation.
    Menendez JA, Mehmi I, Verma VA, Teng PK, Lupu R.
    Mol Carcinog; 2004 Nov 20; 41(3):164-78. PubMed ID: 15390078
    [Abstract] [Full Text] [Related]

  • 15. Palmitate-induced ER stress increases trastuzumab sensitivity in HER2/neu-positive breast cancer cells.
    Baumann J, Wong J, Sun Y, Conklin DS.
    BMC Cancer; 2016 Jul 27; 16():551. PubMed ID: 27464732
    [Abstract] [Full Text] [Related]

  • 16. Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene.
    Menendez JA, Vellon L, Colomer R, Lupu R.
    J Natl Cancer Inst; 2005 Nov 02; 97(21):1611-5. PubMed ID: 16264182
    [Abstract] [Full Text] [Related]

  • 17. Mediterranean diet, olive oil and cancer.
    Colomer R, Menéndez JA.
    Clin Transl Oncol; 2006 Jan 02; 8(1):15-21. PubMed ID: 16632435
    [Abstract] [Full Text] [Related]

  • 18. Prolyl-isomerase Pin1 impairs trastuzumab sensitivity by up-regulating fatty acid synthase expression.
    Yun HJ, Kim JY, Kim G, Choi HS.
    Anticancer Res; 2014 Mar 02; 34(3):1409-16. PubMed ID: 24596388
    [Abstract] [Full Text] [Related]

  • 19. Poly (ADP-ribose) polymerase inhibition enhances trastuzumab antitumour activity in HER2 overexpressing breast cancer.
    García-Parra J, Dalmases A, Morancho B, Arpí O, Menendez S, Sabbaghi M, Zazo S, Chamizo C, Madoz J, Eroles P, Servitja S, Tusquets I, Yelamos J, Lluch A, Arribas J, Rojo F, Rovira A, Albanell J.
    Eur J Cancer; 2014 Oct 02; 50(15):2725-34. PubMed ID: 25128455
    [Abstract] [Full Text] [Related]

  • 20. Antitumor activity of a monoclonal antibody targeting major histocompatibility complex class I-Her2 peptide complexes.
    Jain R, Rawat A, Verma B, Markiewski MM, Weidanz JA.
    J Natl Cancer Inst; 2013 Feb 06; 105(3):202-18. PubMed ID: 23300219
    [Abstract] [Full Text] [Related]

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