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1148 related items for PubMed ID: 15905586

  • 1. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products.
    Ichikawa H, Takada Y, Murakami A, Aggarwal BB.
    J Immunol; 2005 Jun 01; 174(11):7383-92. PubMed ID: 15905586
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  • 2. Indole-3-carbinol suppresses NF-kappaB and IkappaBalpha kinase activation, causing inhibition of expression of NF-kappaB-regulated antiapoptotic and metastatic gene products and enhancement of apoptosis in myeloid and leukemia cells.
    Takada Y, Andreeff M, Aggarwal BB.
    Blood; 2005 Jul 15; 106(2):641-9. PubMed ID: 15811958
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  • 3. Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1.
    Shishodia S, Majumdar S, Banerjee S, Aggarwal BB.
    Cancer Res; 2003 Aug 01; 63(15):4375-83. PubMed ID: 12907607
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  • 4. Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion.
    Takada Y, Kobayashi Y, Aggarwal BB.
    J Biol Chem; 2005 Apr 29; 280(17):17203-12. PubMed ID: 15710601
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  • 5. Betulinic acid suppresses carcinogen-induced NF-kappa B activation through inhibition of I kappa B alpha kinase and p65 phosphorylation: abrogation of cyclooxygenase-2 and matrix metalloprotease-9.
    Takada Y, Aggarwal BB.
    J Immunol; 2003 Sep 15; 171(6):3278-86. PubMed ID: 12960358
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  • 6. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation.
    Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S, Aggarwal BB.
    Mol Pharmacol; 2006 Jan 15; 69(1):195-206. PubMed ID: 16219905
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  • 8. Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalpha kinase activation.
    Sung B, Pandey MK, Aggarwal BB.
    Mol Pharmacol; 2007 Jun 15; 71(6):1703-14. PubMed ID: 17387141
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  • 9. Acetyl-11-keto-beta-boswellic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing NF-kappa B and NF-kappa B-regulated gene expression.
    Takada Y, Ichikawa H, Badmaev V, Aggarwal BB.
    J Immunol; 2006 Mar 01; 176(5):3127-40. PubMed ID: 16493072
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  • 10. Withanolides potentiate apoptosis, inhibit invasion, and abolish osteoclastogenesis through suppression of nuclear factor-kappaB (NF-kappaB) activation and NF-kappaB-regulated gene expression.
    Ichikawa H, Takada Y, Shishodia S, Jayaprakasam B, Nair MG, Aggarwal BB.
    Mol Cancer Ther; 2006 Jun 01; 5(6):1434-45. PubMed ID: 16818501
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  • 12. Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-kappa B signaling pathway.
    Sethi G, Ahn KS, Sandur SK, Lin X, Chaturvedi MM, Aggarwal BB.
    J Biol Chem; 2006 Aug 18; 281(33):23425-35. PubMed ID: 16785236
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  • 13. Protein farnesyltransferase inhibitor (SCH 66336) abolishes NF-kappaB activation induced by various carcinogens and inflammatory stimuli leading to suppression of NF-kappaB-regulated gene expression and up-regulation of apoptosis.
    Takada Y, Khuri FR, Aggarwal BB.
    J Biol Chem; 2004 Jun 18; 279(25):26287-99. PubMed ID: 15090542
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  • 14. Flavopiridol inhibits NF-kappaB activation induced by various carcinogens and inflammatory agents through inhibition of IkappaBalpha kinase and p65 phosphorylation: abrogation of cyclin D1, cyclooxygenase-2, and matrix metalloprotease-9.
    Takada Y, Aggarwal BB.
    J Biol Chem; 2004 Feb 06; 279(6):4750-9. PubMed ID: 14630924
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  • 18. Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis.
    Sethi G, Ahn KS, Sung B, Aggarwal BB.
    Mol Cancer Ther; 2008 Jun 06; 7(6):1604-14. PubMed ID: 18566231
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  • 19. Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: correlation with suppression of COX-2 synthesis.
    Shishodia S, Koul D, Aggarwal BB.
    J Immunol; 2004 Aug 01; 173(3):2011-22. PubMed ID: 15265936
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  • 20. Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherapeutic agents.
    Sandur SK, Ichikawa H, Sethi G, Ahn KS, Aggarwal BB.
    J Biol Chem; 2006 Jun 23; 281(25):17023-17033. PubMed ID: 16624823
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