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158 related items for PubMed ID: 15906351

  • 1. Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity.
    Yoxall V, Kentish P, Coldham N, Kuhnert N, Sauer MJ, Ioannides C.
    Int J Cancer; 2005 Nov 10; 117(3):356-62. PubMed ID: 15906351
    [Abstract] [Full Text] [Related]

  • 2. Up-regulation of the CYP1 family in rat and human liver by the aliphatic isothiocyanates erucin and sulforaphane.
    Hanlon N, Coldham N, Sauer MJ, Ioannides C.
    Toxicology; 2008 Oct 30; 252(1-3):92-8. PubMed ID: 18773935
    [Abstract] [Full Text] [Related]

  • 3. Exposure to isothiocyanates suppresses urinary mutagenicity in rats treated with heterocyclic amine IQ: lack of association with CYP1 activity.
    Hanlon N, Konsue N, Coldham N, Sauer MJ, Ioannides C.
    Nutr Cancer; 2011 Oct 30; 63(2):300-5. PubMed ID: 21298592
    [Abstract] [Full Text] [Related]

  • 4. Modulation of rat hepatic and pulmonary cytochromes P450 and phase II enzyme systems by erucin, an isothiocyanate structurally related to sulforaphane.
    Hanlon N, Okpara A, Coldham N, Sauer MJ, Ioannides C.
    J Agric Food Chem; 2008 Sep 10; 56(17):7866-71. PubMed ID: 18680373
    [Abstract] [Full Text] [Related]

  • 5. Modulation of rat pulmonary carcinogen-metabolising enzyme systems by the isothiocyanates erucin and sulforaphane.
    Hanlon N, Coldham N, Sauer MJ, Ioannides C.
    Chem Biol Interact; 2009 Jan 27; 177(2):115-20. PubMed ID: 18823965
    [Abstract] [Full Text] [Related]

  • 6. The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer.
    Abdull Razis AF, Iori R, Ioannides C.
    Int J Cancer; 2011 Jun 15; 128(12):2775-82. PubMed ID: 20726001
    [Abstract] [Full Text] [Related]

  • 7. A glucosinolate-rich extract of Japanese Daikon perturbs carcinogen-metabolizing enzyme systems in rat, being a potent inducer of hepatic glutathione S-transferase.
    Abdull Razis AF, De Nicola GR, Pagnotta E, Iori R, Ioannides C.
    Eur J Nutr; 2013 Apr 15; 52(3):1279-85. PubMed ID: 22710810
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  • 11. 4-Methylsulfanyl-3-butenyl isothiocyanate derived from glucoraphasatin is a potent inducer of rat hepatic phase II enzymes and a potential chemopreventive agent.
    Abdull Razis AF, De Nicola GR, Pagnotta E, Iori R, Ioannides C.
    Arch Toxicol; 2012 Feb 15; 86(2):183-94. PubMed ID: 21960141
    [Abstract] [Full Text] [Related]

  • 12. Cancer chemopreventive potential of sulforamate, a novel analogue of sulforaphane that induces phase 2 drug-metabolizing enzymes.
    Gerhäuser C, You M, Liu J, Moriarty RM, Hawthorne M, Mehta RG, Moon RC, Pezzuto JM.
    Cancer Res; 1997 Jan 15; 57(2):272-8. PubMed ID: 9000567
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  • 13. Inhibition of cytochromes P-450 and induction of glutathione S-transferases by sulforaphane in primary human and rat hepatocytes.
    Mahéo K, Morel F, Langouët S, Kramer H, Le Ferrec E, Ketterer B, Guillouzo A.
    Cancer Res; 1997 Sep 01; 57(17):3649-52. PubMed ID: 9288764
    [Abstract] [Full Text] [Related]

  • 14. Glucoraphanin, the bioprecursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, induces phase-I xenobiotic metabolizing enzymes and increases free radical generation in rat liver.
    Perocco P, Bronzetti G, Canistro D, Valgimigli L, Sapone A, Affatato A, Pedulli GF, Pozzetti L, Broccoli M, Iori R, Barillari J, Sblendorio V, Legator MS, Paolini M, Abdel-Rahman SZ.
    Mutat Res; 2006 Mar 20; 595(1-2):125-36. PubMed ID: 16442570
    [Abstract] [Full Text] [Related]

  • 15. Up-regulation of cytochrome P450 and phase II enzyme systems in rat precision-cut rat lung slices by the intact glucosinolates, glucoraphanin and glucoerucin.
    Abdull Razis AF, Bagatta M, De Nicola GR, Iori R, Ioannides C.
    Lung Cancer; 2011 Mar 20; 71(3):298-305. PubMed ID: 20638746
    [Abstract] [Full Text] [Related]

  • 16. Contrasting effects of acute and chronic dietary exposure to 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ) on xenobiotic metabolising enzymes in the male Fischer 344 rat: implications for chemoprevention studies.
    McPherson RA, Tingle MD, Ferguson LR.
    Eur J Nutr; 2001 Feb 20; 40(1):39-47. PubMed ID: 11315504
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  • 17. Mechanisms of inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation in mouse by dietary phenethyl isothiocyanate.
    Smith TJ, Guo Z, Li C, Ning SM, Thomas PE, Yang CS.
    Cancer Res; 1993 Jul 15; 53(14):3276-82. PubMed ID: 8324738
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  • 18. Intact glucosinolates modulate hepatic cytochrome P450 and phase II conjugation activities and may contribute directly to the chemopreventive activity of cruciferous vegetables.
    Abdull Razis AF, Bagatta M, De Nicola GR, Iori R, Ioannides C.
    Toxicology; 2010 Nov 09; 277(1-3):74-85. PubMed ID: 20833222
    [Abstract] [Full Text] [Related]

  • 19. Antimutagenic effects of wheat bran diet through modification of xenobiotic metabolising enzymes.
    Helsby NA, Zhu S, Pearson AE, Tingle MD, Ferguson LR.
    Mutat Res; 2000 Nov 06; 454(1-2):77-88. PubMed ID: 11035162
    [Abstract] [Full Text] [Related]

  • 20. Effects of phenethyl isothiocyanate, a carcinogenesis inhibitor, on xenobiotic-metabolizing enzymes and nitrosamine metabolism in rats.
    Guo Z, Smith TJ, Wang E, Sadrieh N, Ma Q, Thomas PE, Yang CS.
    Carcinogenesis; 1992 Dec 06; 13(12):2205-10. PubMed ID: 1473225
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