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218 related items for PubMed ID: 15906378
1. Restoration of DSCR1 to disomy in the trisomy 16 mouse model of Down syndrome does not correct cardiac or craniofacial development anomalies. Lange AW, Rothermel BA, Yutzey KE. Dev Dyn; 2005 Jul; 233(3):954-63. PubMed ID: 15906378 [Abstract] [Full Text] [Related]
2. DSCR1 gene expression is dependent on NFATc1 during cardiac valve formation and colocalizes with anomalous organ development in trisomy 16 mice. Lange AW, Molkentin JD, Yutzey KE. Dev Biol; 2004 Feb 15; 266(2):346-60. PubMed ID: 14738882 [Abstract] [Full Text] [Related]
3. VEGF selectively induces Down syndrome critical region 1 gene expression in endothelial cells: a mechanism for feedback regulation of angiogenesis? Yao YG, Duh EJ. Biochem Biophys Res Commun; 2004 Aug 27; 321(3):648-56. PubMed ID: 15358155 [Abstract] [Full Text] [Related]
4. Trisomy of the Dscr1 gene suppresses early progression of pancreatic intraepithelial neoplasia driven by oncogenic Kras. Lee JC, Shin J, Baek KH. Biochem Biophys Res Commun; 2013 Oct 11; 440(1):50-5. PubMed ID: 24041692 [Abstract] [Full Text] [Related]
5. DSCR1 (ADAPT78) lethality: evidence for a protective effect of trisomy 21 genes? Kluetzman KS, Perez AV, Crawford DR. Biochem Biophys Res Commun; 2005 Nov 18; 337(2):595-601. PubMed ID: 16198305 [Abstract] [Full Text] [Related]
6. DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways. Fuentes JJ, Genescà L, Kingsbury TJ, Cunningham KW, Pérez-Riba M, Estivill X, de la Luna S. Hum Mol Genet; 2000 Jul 01; 9(11):1681-90. PubMed ID: 10861295 [Abstract] [Full Text] [Related]
7. A new human gene from the Down syndrome critical region encodes a proline-rich protein highly expressed in fetal brain and heart. Fuentes JJ, Pritchard MA, Planas AM, Bosch A, Ferrer I, Estivill X. Hum Mol Genet; 1995 Oct 01; 4(10):1935-44. PubMed ID: 8595418 [Abstract] [Full Text] [Related]
8. NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21. Arron JR, Winslow MM, Polleri A, Chang CP, Wu H, Gao X, Neilson JR, Chen L, Heit JJ, Kim SK, Yamasaki N, Miyakawa T, Francke U, Graef IA, Crabtree GR. Nature; 2006 Jun 01; 441(7093):595-600. PubMed ID: 16554754 [Abstract] [Full Text] [Related]
9. Down syndrome critical region-1 is a transcriptional target of nuclear factor of activated T cells-c1 within the endocardium during heart development. Wu H, Kao SC, Barrientos T, Baldwin SH, Olson EN, Crabtree GR, Zhou B, Chang CP. J Biol Chem; 2007 Oct 19; 282(42):30673-9. PubMed ID: 17693409 [Abstract] [Full Text] [Related]
10. A single extra copy of Dscr1 improves survival of mice developing spontaneous lung tumors through suppression of tumor angiogenesis. Shin J, Lee JC, Baek KH. Cancer Lett; 2014 Jan 01; 342(1):70-81. PubMed ID: 24051307 [Abstract] [Full Text] [Related]
11. Depolarization of neural cells induces transcription of the Down syndrome critical region 1 isoform 4 via a calcineurin/nuclear factor of activated T cells-dependent pathway. Cano E, Canellada A, Minami T, Iglesias T, Redondo JM. J Biol Chem; 2005 Aug 19; 280(33):29435-43. PubMed ID: 15975916 [Abstract] [Full Text] [Related]
12. Mutational analyses of the signals involved in the subcellular location of DSCR1. Pfister SC, Machado-Santelli GM, Han SW, Henrique-Silva F. BMC Cell Biol; 2002 Sep 11; 3():24. PubMed ID: 12225619 [Abstract] [Full Text] [Related]
13. Down syndrome candidate region 1 isoform 1 mediates angiogenesis through the calcineurin-NFAT pathway. Qin L, Zhao D, Liu X, Nagy JA, Hoang MV, Brown LF, Dvorak HF, Zeng H. Mol Cancer Res; 2006 Nov 11; 4(11):811-20. PubMed ID: 17114339 [Abstract] [Full Text] [Related]
14. [Molecular Mechanism Underlying Abnormal Differentiation of Neural Progenitor Cells in the Developing Down Syndrome Brain]. Kurabayashi N, Sanada K. Yakugaku Zasshi; 2017 Nov 11; 137(7):795-800. PubMed ID: 28674289 [Abstract] [Full Text] [Related]
15. Down syndrome critical region protein 1 (DSCR1), a novel VEGF target gene that regulates expression of inflammatory markers on activated endothelial cells. Hesser BA, Liang XH, Camenisch G, Yang S, Lewin DA, Scheller R, Ferrara N, Gerber HP. Blood; 2004 Jul 01; 104(1):149-58. PubMed ID: 15016650 [Abstract] [Full Text] [Related]
16. Cooperation to amplify gene-dosage-imbalance effects. de la Luna S, Estivill X. Trends Mol Med; 2006 Oct 01; 12(10):451-4. PubMed ID: 16919501 [Abstract] [Full Text] [Related]
17. The murine DSCR1-like (Down syndrome candidate region 1) gene family: conserved synteny with the human orthologous genes. Strippoli P, Petrini M, Lenzi L, Carinci P, Zannotti M. Gene; 2000 Oct 31; 257(2):223-32. PubMed ID: 11080588 [Abstract] [Full Text] [Related]
18. Genetics. The critical region in trisomy 21. Nelson DL, Gibbs RA. Science; 2004 Oct 22; 306(5696):619-21. PubMed ID: 15499000 [No Abstract] [Full Text] [Related]
19. Congenital heart disease reminiscent of partial trisomy 2p syndrome in mice transgenic for the transcription factor Lbh. Briegel KJ, Baldwin HS, Epstein JA, Joyner AL. Development; 2005 Jul 22; 132(14):3305-16. PubMed ID: 15958514 [Abstract] [Full Text] [Related]
20. A calcineurin inhibitory protein overexpressed in Down's syndrome interacts with the product of a ubiquitously expressed transcript. Silveira HC, Sommer CA, Soares-Costa A, Henrique-Silva F. Braz J Med Biol Res; 2004 Jun 22; 37(6):785-9. PubMed ID: 15264020 [Abstract] [Full Text] [Related] Page: [Next] [New Search]