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127 related items for PubMed ID: 15949711

  • 1. Transgenic mice overexpressing SREBP-1a under the control of the PEPCK promoter exhibit insulin resistance, but not diabetes.
    Takahashi A, Shimano H, Nakagawa Y, Yamamoto T, Motomura K, Matsuzaka T, Sone H, Suzuki H, Toyoshima H, Yamada N.
    Biochim Biophys Acta; 2005 Jun 10; 1740(3):427-33. PubMed ID: 15949711
    [Abstract] [Full Text] [Related]

  • 2. A new transgenic rat model of hepatic steatosis and the metabolic syndrome.
    Qi NR, Wang J, Zidek V, Landa V, Mlejnek P, Kazdová L, Pravenec M, Kurtz TW.
    Hypertension; 2005 May 10; 45(5):1004-11. PubMed ID: 15809359
    [Abstract] [Full Text] [Related]

  • 3. Overexpression of sterol regulatory element-binding protein-1a in mouse adipose tissue produces adipocyte hypertrophy, increased fatty acid secretion, and fatty liver.
    Horton JD, Shimomura I, Ikemoto S, Bashmakov Y, Hammer RE.
    J Biol Chem; 2003 Sep 19; 278(38):36652-60. PubMed ID: 12855691
    [Abstract] [Full Text] [Related]

  • 4. Transgenic mice overexpressing nuclear SREBP-1c in pancreatic beta-cells.
    Takahashi A, Motomura K, Kato T, Yoshikawa T, Nakagawa Y, Yahagi N, Sone H, Suzuki H, Toyoshima H, Yamada N, Shimano H.
    Diabetes; 2005 Feb 19; 54(2):492-9. PubMed ID: 15677507
    [Abstract] [Full Text] [Related]

  • 5. Transgenic Mice Overexpressing SREBP-1a in Male ob/ob Mice Exhibit Lipodystrophy and Exacerbate Insulin Resistance.
    Ohno H, Matsuzaka T, Tang N, Sharma R, Motomura K, Shimura T, Satoh A, Han SI, Takeuchi Y, Aita Y, Iwasaki H, Yatoh S, Suzuki H, Sekiya M, Nakagawa Y, Sone H, Yahagi N, Yamada N, Higami Y, Shimano H.
    Endocrinology; 2018 Jun 01; 159(6):2308-2323. PubMed ID: 29668871
    [Abstract] [Full Text] [Related]

  • 6. Yin yang 1 protein negatively regulates high-density lipoprotein receptor gene transcription by disrupting binding of sterol regulatory element binding protein to the sterol regulatory element.
    Shea-Eaton W, Lopez D, McLean MP.
    Endocrinology; 2001 Jan 01; 142(1):49-58. PubMed ID: 11145566
    [Abstract] [Full Text] [Related]

  • 7. SREBP transcription factors: master regulators of lipid homeostasis.
    Eberlé D, Hegarty B, Bossard P, Ferré P, Foufelle F.
    Biochimie; 2004 Nov 01; 86(11):839-48. PubMed ID: 15589694
    [Abstract] [Full Text] [Related]

  • 8. Insulin-independent induction of sterol regulatory element-binding protein-1c expression in the livers of streptozotocin-treated mice.
    Matsuzaka T, Shimano H, Yahagi N, Amemiya-Kudo M, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Tomita S, Sekiya M, Hasty A, Nakagawa Y, Sone H, Toyoshima H, Ishibashi S, Osuga J, Yamada N.
    Diabetes; 2004 Mar 01; 53(3):560-9. PubMed ID: 14988238
    [Abstract] [Full Text] [Related]

  • 9. Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.
    Shimano H, Horton JD, Hammer RE, Shimomura I, Brown MS, Goldstein JL.
    J Clin Invest; 1996 Oct 01; 98(7):1575-84. PubMed ID: 8833906
    [Abstract] [Full Text] [Related]

  • 10. Conditional response of the human steroidogenic acute regulatory protein gene promoter to sterol regulatory element binding protein-1a.
    Christenson LK, Osborne TF, McAllister JM, Strauss JF.
    Endocrinology; 2001 Jan 01; 142(1):28-36. PubMed ID: 11145563
    [Abstract] [Full Text] [Related]

  • 11. Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis.
    Engelking LJ, Kuriyama H, Hammer RE, Horton JD, Brown MS, Goldstein JL, Liang G.
    J Clin Invest; 2004 Apr 01; 113(8):1168-75. PubMed ID: 15085196
    [Abstract] [Full Text] [Related]

  • 12. PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity.
    Matsumoto M, Ogawa W, Akimoto K, Inoue H, Miyake K, Furukawa K, Hayashi Y, Iguchi H, Matsuki Y, Hiramatsu R, Shimano H, Yamada N, Ohno S, Kasuga M, Noda T.
    J Clin Invest; 2003 Sep 01; 112(6):935-44. PubMed ID: 12975478
    [Abstract] [Full Text] [Related]

  • 13. Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c.
    Hegarty BD, Bobard A, Hainault I, Ferré P, Bossard P, Foufelle F.
    Proc Natl Acad Sci U S A; 2005 Jan 18; 102(3):791-6. PubMed ID: 15637161
    [Abstract] [Full Text] [Related]

  • 14. Effects of atorvastatin on glucose metabolism and insulin resistance in KK/Ay mice.
    Suzuki M, Kakuta H, Takahashi A, Shimano H, Tada-Iida K, Yokoo T, Kihara R, Yamada N.
    J Atheroscler Thromb; 2005 Jan 18; 12(2):77-84. PubMed ID: 15942117
    [Abstract] [Full Text] [Related]

  • 15. Adenovirus-mediated overexpression of sterol regulatory element binding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice.
    Bécard D, Hainault I, Azzout-Marniche D, Bertry-Coussot L, Ferré P, Foufelle F.
    Diabetes; 2001 Nov 18; 50(11):2425-30. PubMed ID: 11679417
    [Abstract] [Full Text] [Related]

  • 16. Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes.
    Horton JD, Shah NA, Warrington JA, Anderson NN, Park SW, Brown MS, Goldstein JL.
    Proc Natl Acad Sci U S A; 2003 Oct 14; 100(21):12027-32. PubMed ID: 14512514
    [Abstract] [Full Text] [Related]

  • 17. Effect of sterol regulatory element binding protein-1a on the mitochondrial protein pattern in human liver cells detected by 2D-DIGE.
    Lehr S, Kotzka J, Avci H, Knebel B, Muller S, Hanisch FG, Jacob S, Haak C, Susanto F, Muller-Wieland D.
    Biochemistry; 2005 Apr 05; 44(13):5117-28. PubMed ID: 15794649
    [Abstract] [Full Text] [Related]

  • 18. Sterol regulatory element binding protein-1a regulation of the steroidogenic acute regulatory protein gene.
    Shea-Eaton WK, Trinidad MJ, Lopez D, Nackley A, McLean MP.
    Endocrinology; 2001 Apr 05; 142(4):1525-33. PubMed ID: 11250933
    [Abstract] [Full Text] [Related]

  • 19. Overexpression of c-myc in diabetic mice restores altered expression of the transcription factor genes that regulate liver metabolism.
    Riu E, Ferre T, Mas A, Hidalgo A, Franckhauser S, Bosch F.
    Biochem J; 2002 Dec 15; 368(Pt 3):931-7. PubMed ID: 12230428
    [Abstract] [Full Text] [Related]

  • 20. Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice.
    Yahagi N, Shimano H, Hasty AH, Matsuzaka T, Ide T, Yoshikawa T, Amemiya-Kudo M, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Nagai R, Ishibashi S, Yamada N.
    J Biol Chem; 2002 May 31; 277(22):19353-7. PubMed ID: 11923308
    [Abstract] [Full Text] [Related]

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