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313 related items for PubMed ID: 15951399

  • 1. Lecozotan (SRA-333): a selective serotonin 1A receptor antagonist that enhances the stimulated release of glutamate and acetylcholine in the hippocampus and possesses cognitive-enhancing properties.
    Schechter LE, Smith DL, Rosenzweig-Lipson S, Sukoff SJ, Dawson LA, Marquis K, Jones D, Piesla M, Andree T, Nawoschik S, Harder JA, Womack MD, Buccafusco J, Terry AV, Hoebel B, Rada P, Kelly M, Abou-Gharbia M, Barrett JE, Childers W.
    J Pharmacol Exp Ther; 2005 Sep; 314(3):1274-89. PubMed ID: 15951399
    [Abstract] [Full Text] [Related]

  • 2. The serotonin1A receptor partial agonist S15535 [4-(benzodioxan-5-yl)1-(indan-2-yl)piperazine] enhances cholinergic transmission and cognitive function in rodents: a combined neurochemical and behavioral analysis.
    Millan MJ, Gobert A, Roux S, Porsolt R, Meneses A, Carli M, Di Cara B, Jaffard R, Rivet JM, Lestage P, Mocaer E, Peglion JL, Dekeyne A.
    J Pharmacol Exp Ther; 2004 Oct; 311(1):190-203. PubMed ID: 15146031
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  • 3. 5-Hydroxytryptamine 1A receptor blockade facilitates aversive learning in mice: interactions with cholinergic and glutamatergic mechanisms.
    Madjid N, Tottie EE, Lüttgen M, Meister B, Sandin J, Kuzmin A, Stiedl O, Ogren SO.
    J Pharmacol Exp Ther; 2006 Feb; 316(2):581-91. PubMed ID: 16223872
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  • 4. Contrasting contribution of 5-hydroxytryptamine 1A receptor activation to neurochemical profile of novel antipsychotics: frontocortical dopamine and hippocampal serotonin release in rat brain.
    Assié MB, Ravailhe V, Faucillon V, Newman-Tancredi A.
    J Pharmacol Exp Ther; 2005 Oct; 315(1):265-72. PubMed ID: 15987834
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  • 5. Correlating efficacy in rodent cognition models with in vivo 5-hydroxytryptamine1a receptor occupancy by a novel antagonist, (R)-N-(2-methyl-(4-indolyl-1-piperazinyl)ethyl)-N-(2-pyridinyl)-cyclohexane carboxamide (WAY-101405).
    Hirst WD, Andree TH, Aschmies S, Childers WE, Comery TA, Dawson LA, Day M, Feingold IB, Grauer SM, Harrison BL, Hughes ZA, Kao J, Kelly MG, van der Lee H, Rosenzweig-Lipson S, Saab AL, Smith DL, Sullivan K, Rizzo SJ, Tio C, Zhang MY, Schechter LE.
    J Pharmacol Exp Ther; 2008 Apr; 325(1):134-45. PubMed ID: 18182558
    [Abstract] [Full Text] [Related]

  • 6. In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates, the selective 5-hydroxytryptamine 1a agonist (R)-(+)-8-OHDPAT inhibits levodopa-induced dyskinesia but only with\ increased motor disability.
    Iravani MM, Tayarani-Binazir K, Chu WB, Jackson MJ, Jenner P.
    J Pharmacol Exp Ther; 2006 Dec; 319(3):1225-34. PubMed ID: 16959959
    [Abstract] [Full Text] [Related]

  • 7. The counteraction of opioid-induced ventilatory depression by the serotonin 1A-agonist 8-OH-DPAT does not antagonize antinociception in rats in situ and in vivo.
    Guenther U, Manzke T, Wrigge H, Dutschmann M, Zinserling J, Putensen C, Hoeft A.
    Anesth Analg; 2009 Apr; 108(4):1169-76. PubMed ID: 19299781
    [Abstract] [Full Text] [Related]

  • 8. The selective 5-HT(1A) receptor antagonist NAD-299 increases acetylcholine release but not extracellular glutamate levels in the frontal cortex and hippocampus of awake rat.
    Kehr J, Hu XJ, Yoshitake T, Wang FH, Osborne P, Stenfors C, Ogren SO.
    Eur Neuropsychopharmacol; 2010 Jul; 20(7):487-500. PubMed ID: 20413275
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  • 12. Short-term effects of 3,4-methylen-dioxy-metamphetamine (MDMA) on 5-HT(1A) receptors in the rat hippocampus.
    Giannaccini G, Betti L, Pirone A, Palego L, Fabiani O, Fabbrini L, Mascia G, Giusti L, Macchia M, Giusiani M, Martini C, Lucacchini A.
    Neurochem Int; 2007 Dec; 51(8):496-506. PubMed ID: 17602794
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  • 13. Allosteric modulation of 5-HT(1A) receptors by zinc: Binding studies.
    Barrondo S, Sallés J.
    Neuropharmacology; 2009 Feb; 56(2):455-62. PubMed ID: 18951909
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  • 15. Serotonin 5-HT receptor blockade enhances Ca(2+)/calmodulin-dependent protein kinase II function and membrane expression of AMPA receptor subunits in the rat hippocampus: implications for memory formation.
    Schiapparelli L, Del Río J, Frechilla D.
    J Neurochem; 2005 Aug; 94(4):884-95. PubMed ID: 16092936
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  • 16. Pharmacological studies of 8-OH-DPAT-induced pupillary dilation in anesthetized rats.
    Yu Y, Ramage AG, Koss MC.
    Eur J Pharmacol; 2004 Apr 12; 489(3):207-13. PubMed ID: 15087245
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  • 17. WAY-100635 antagonist-induced plasticity of 5-HT receptors: regulatory differences between a stable cell line and an in vivo native system.
    Khawaja XZ, Smith DL, Nawoschik SP, Zhang J, Dunlop J, Dilks DW, Olsen M, Schechter LE.
    J Neurochem; 2006 Jul 12; 98(1):134-45. PubMed ID: 16805803
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  • 18. S 15535, a novel benzodioxopiperazine ligand of serotonin (5-HT)1A receptors: II. Modulation of hippocampal serotonin release in relation to potential anxiolytic properties.
    Millan MJ, Hjorth S, Samanin R, Schreiber R, Jaffard R, De Ladonchamps B, Veiga S, Goument B, Peglion JL, Spedding M, Brocco M.
    J Pharmacol Exp Ther; 1997 Jul 12; 282(1):148-61. PubMed ID: 9223550
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  • 19. Unilateral lesion of the nigrostriatal pathway induces an increase of neuronal firing of the midbrain raphe nuclei 5-HT neurons and a decrease of their response to 5-HT(1A) receptor stimulation in the rat.
    Wang S, Zhang QJ, Liu J, Wu ZH, Wang T, Gui ZH, Chen L, Wang Y.
    Neuroscience; 2009 Mar 17; 159(2):850-61. PubMed ID: 19174182
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  • 20. Stimulation of 5-HT(1A) receptors in the dorsal raphe ameliorates the impairment of spatial learning caused by intrahippocampal 7-chloro-kynurenic acid in naive and pretrained rats.
    Carli M, Balducci C, Samanin R.
    Psychopharmacology (Berl); 2001 Oct 17; 158(1):39-47. PubMed ID: 11685382
    [Abstract] [Full Text] [Related]

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