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380 related items for PubMed ID: 15952035

  • 1. TRPM2: a calcium influx pathway regulated by oxidative stress and the novel second messenger ADP-ribose.
    Kühn FJ, Heiner I, Lückhoff A.
    Pflugers Arch; 2005 Oct; 451(1):212-9. PubMed ID: 15952035
    [Abstract] [Full Text] [Related]

  • 2. A calcium influx pathway regulated separately by oxidative stress and ADP-Ribose in TRPM2 channels: single channel events.
    Naziroğlu M, Lückhoff A.
    Neurochem Res; 2008 Jul; 33(7):1256-62. PubMed ID: 18259858
    [Abstract] [Full Text] [Related]

  • 3. New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose.
    Naziroğlu M.
    Neurochem Res; 2007 Nov; 32(11):1990-2001. PubMed ID: 17562166
    [Abstract] [Full Text] [Related]

  • 4. TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase.
    Fonfria E, Marshall IC, Benham CD, Boyfield I, Brown JD, Hill K, Hughes JP, Skaper SD, McNulty S.
    Br J Pharmacol; 2004 Sep; 143(1):186-92. PubMed ID: 15302683
    [Abstract] [Full Text] [Related]

  • 5. Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel.
    Tóth B, Csanády L.
    J Biol Chem; 2010 Sep 24; 285(39):30091-102. PubMed ID: 20650899
    [Abstract] [Full Text] [Related]

  • 6. TRPM2 cation channels, oxidative stress and neurological diseases: where are we now?
    Nazıroğlu M.
    Neurochem Res; 2011 Mar 24; 36(3):355-66. PubMed ID: 21140288
    [Abstract] [Full Text] [Related]

  • 7. Structures and gating mechanism of human TRPM2.
    Wang L, Fu TM, Zhou Y, Xia S, Greka A, Wu H.
    Science; 2018 Dec 21; 362(6421):. PubMed ID: 30467180
    [Abstract] [Full Text] [Related]

  • 8. Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349.
    Fliegert R, Watt JM, Schöbel A, Rozewitz MD, Moreau C, Kirchberger T, Thomas MP, Sick W, Araujo AC, Harneit A, Potter BVL, Guse AH.
    Biochem J; 2017 Jun 16; 474(13):2159-2175. PubMed ID: 28515263
    [Abstract] [Full Text] [Related]

  • 9. The Poly(ADP-ribose) polymerase PARP-1 is required for oxidative stress-induced TRPM2 activation in lymphocytes.
    Buelow B, Song Y, Scharenberg AM.
    J Biol Chem; 2008 Sep 05; 283(36):24571-83. PubMed ID: 18599483
    [Abstract] [Full Text] [Related]

  • 10. Endogenous ADP-ribose enables calcium-regulated cation currents through TRPM2 channels in neutrophil granulocytes.
    Heiner I, Eisfeld J, Warnstedt M, Radukina N, Jüngling E, Lückhoff A.
    Biochem J; 2006 Sep 01; 398(2):225-32. PubMed ID: 16719842
    [Abstract] [Full Text] [Related]

  • 11. Regulation of TRPM2 by extra- and intracellular calcium.
    Starkus J, Beck A, Fleig A, Penner R.
    J Gen Physiol; 2007 Oct 01; 130(4):427-40. PubMed ID: 17893195
    [Abstract] [Full Text] [Related]

  • 12. Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels.
    Kolisek M, Beck A, Fleig A, Penner R.
    Mol Cell; 2005 Apr 01; 18(1):61-9. PubMed ID: 15808509
    [Abstract] [Full Text] [Related]

  • 13. Regulation of TRPM2 channels in neutrophil granulocytes by ADP-ribose: a promising pharmacological target.
    Heiner I, Radukina N, Eisfeld J, Kühn F, Lückhoff A.
    Naunyn Schmiedebergs Arch Pharmacol; 2005 Apr 01; 371(4):325-33. PubMed ID: 15841395
    [Abstract] [Full Text] [Related]

  • 14. TRPM2.
    Eisfeld J, Lückhoff A.
    Handb Exp Pharmacol; 2007 Apr 01; (179):237-52. PubMed ID: 17217061
    [Abstract] [Full Text] [Related]

  • 15. Mechanism of TRPM2 channel gating revealed by cryo-EM.
    Xia S, Wang L, Fu TM, Wu H.
    FEBS J; 2019 Sep 01; 286(17):3333-3339. PubMed ID: 31144442
    [Abstract] [Full Text] [Related]

  • 16. Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels.
    Perraud AL, Takanishi CL, Shen B, Kang S, Smith MK, Schmitz C, Knowles HM, Ferraris D, Li W, Zhang J, Stoddard BL, Scharenberg AM.
    J Biol Chem; 2005 Feb 18; 280(7):6138-48. PubMed ID: 15561722
    [Abstract] [Full Text] [Related]

  • 17. TRPM2: a multifunctional ion channel for oxidative stress sensing.
    Ru X, Yao X.
    Sheng Li Xue Bao; 2014 Feb 25; 66(1):7-15. PubMed ID: 24553864
    [Abstract] [Full Text] [Related]

  • 18. Intracellular calcium activates TRPM2 and its alternative spliced isoforms.
    Du J, Xie J, Yue L.
    Proc Natl Acad Sci U S A; 2009 Apr 28; 106(17):7239-44. PubMed ID: 19372375
    [Abstract] [Full Text] [Related]

  • 19. TRPM2 channels in alveolar epithelial cells mediate bleomycin-induced lung inflammation.
    Yonezawa R, Yamamoto S, Takenaka M, Kage Y, Negoro T, Toda T, Ohbayashi M, Numata T, Nakano Y, Yamamoto T, Mori Y, Ishii M, Shimizu S.
    Free Radic Biol Med; 2016 Jan 28; 90():101-13. PubMed ID: 26600069
    [Abstract] [Full Text] [Related]

  • 20. Sensitization of H2O2-induced TRPM2 activation and subsequent interleukin-8 (CXCL8) production by intracellular Fe(2+) in human monocytic U937 cells.
    Shimizu S, Yonezawa R, Negoro T, Yamamoto S, Numata T, Ishii M, Mori Y, Toda T.
    Int J Biochem Cell Biol; 2015 Nov 28; 68():119-27. PubMed ID: 26386353
    [Abstract] [Full Text] [Related]

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