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147 related items for PubMed ID: 15955696

  • 1. Estrogen receptor alpha is required for mammary development and the induction of mammary hyperplasia and epigenetic alterations in the aromatase transgenic mice.
    Tekmal RR, Liu YG, Nair HB, Jones J, Perla RP, Lubahn DB, Korach KS, Kirma N.
    J Steroid Biochem Mol Biol; 2005 May; 95(1-5):9-15. PubMed ID: 15955696
    [Abstract] [Full Text] [Related]

  • 2. HER-2/neu x aromatase double transgenic mice model: the effects of aromatase overexpression on mammary tumorigenesis.
    Tekmal RR, Nair HB, Perla RP, Kirma N.
    J Steroid Biochem Mol Biol; 2007 May; 106(1-5):111-8. PubMed ID: 17604617
    [Abstract] [Full Text] [Related]

  • 3. Overexpression of aromatase leads to hyperplasia and changes in the expression of genes involved in apoptosis, cell cycle, growth, and tumor suppressor functions in the mammary glands of transgenic mice.
    Kirma N, Gill K, Mandava U, Tekmal RR.
    Cancer Res; 2001 Mar 01; 61(5):1910-8. PubMed ID: 11280746
    [Abstract] [Full Text] [Related]

  • 4. Estrogen receptor-alpha expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice.
    Feng Y, Manka D, Wagner KU, Khan SA.
    Proc Natl Acad Sci U S A; 2007 Sep 11; 104(37):14718-23. PubMed ID: 17785410
    [Abstract] [Full Text] [Related]

  • 5. Tissue distribution and quantitative analysis of estrogen receptor-alpha (ERalpha) and estrogen receptor-beta (ERbeta) messenger ribonucleic acid in the wild-type and ERalpha-knockout mouse.
    Couse JF, Lindzey J, Grandien K, Gustafsson JA, Korach KS.
    Endocrinology; 1997 Nov 11; 138(11):4613-21. PubMed ID: 9348186
    [Abstract] [Full Text] [Related]

  • 6. Mammary gland development in transgenic male mice expressing human P450 aromatase.
    Li X, Wärri A, Mäkelä S, Ahonen T, Streng T, Santti R, Poutanen M.
    Endocrinology; 2002 Oct 11; 143(10):4074-83. PubMed ID: 12239119
    [Abstract] [Full Text] [Related]

  • 7. A mouse mammary tumor virus-Wnt-1 transgene induces mammary gland hyperplasia and tumorigenesis in mice lacking estrogen receptor-alpha.
    Bocchinfuso WP, Hively WP, Couse JF, Varmus HE, Korach KS.
    Cancer Res; 1999 Apr 15; 59(8):1869-76. PubMed ID: 10213494
    [Abstract] [Full Text] [Related]

  • 8. Chromosomal mapping and quantitative analysis of estrogen-related receptor alpha-1, estrogen receptors alpha and beta and progesterone receptor in the bovine mammary gland.
    Connor EE, Wood DL, Sonstegard TS, da Mota AF, Bennett GL, Williams JL, Capuco AV.
    J Endocrinol; 2005 Jun 15; 185(3):593-603. PubMed ID: 15930184
    [Abstract] [Full Text] [Related]

  • 9. Estrogen metabolites and breast cancer.
    Santen RJ, Yue W, Wang JP.
    Steroids; 2015 Jul 15; 99(Pt A):61-6. PubMed ID: 25168343
    [Abstract] [Full Text] [Related]

  • 10. Estrogen receptors alfa (ERalpha) and beta (ERbeta) differentially regulate proliferation and apoptosis of the normal murine mammary epithelial cell line HC11.
    Helguero LA, Faulds MH, Gustafsson JA, Haldosén LA.
    Oncogene; 2005 Oct 06; 24(44):6605-16. PubMed ID: 16007178
    [Abstract] [Full Text] [Related]

  • 11. Overexpression of int-5/aromatase in mammary glands of transgenic mice results in the induction of hyperplasia and nuclear abnormalities.
    Tekmal RR, Ramachandra N, Gubba S, Durgam VR, Mantione J, Toda K, Shizuta Y, Dillehay DL.
    Cancer Res; 1996 Jul 15; 56(14):3180-5. PubMed ID: 8764102
    [Abstract] [Full Text] [Related]

  • 12. The effects of aromatase overexpression on mammary growth and gene expression in the aromatase x transforming growth factor alpha double transgenic mice.
    Kirma N, Mandava U, Wuichet K, Tekmal RR.
    J Steroid Biochem Mol Biol; 2001 Nov 15; 78(5):419-26. PubMed ID: 11738552
    [Abstract] [Full Text] [Related]

  • 13. Steroid hormone receptor expression and proliferation in rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
    Qiu C, Shan L, Yu M, Snyderwine EG.
    Carcinogenesis; 2005 Apr 15; 26(4):763-9. PubMed ID: 15637090
    [Abstract] [Full Text] [Related]

  • 14. Comparison of increased aromatase versus ERα in the generation of mammary hyperplasia and cancer.
    Díaz-Cruz ES, Sugimoto Y, Gallicano GI, Brueggemeier RW, Furth PA.
    Cancer Res; 2011 Aug 15; 71(16):5477-87. PubMed ID: 21840986
    [Abstract] [Full Text] [Related]

  • 15. Tumors initiated by constitutive Cdk2 activation exhibit transforming growth factor beta resistance and acquire paracrine mitogenic stimulation during progression.
    Corsino P, Davis B, Law M, Chytil A, Forrester E, Nørgaard P, Teoh N, Law B.
    Cancer Res; 2007 Apr 01; 67(7):3135-44. PubMed ID: 17409420
    [Abstract] [Full Text] [Related]

  • 16. Loss of cyclin D1 in concert with deregulated estrogen receptor alpha expression induces DNA damage response activation and interrupts mammary gland morphogenesis.
    Frech MS, Torre KM, Robinson GW, Furth PA.
    Oncogene; 2008 May 15; 27(22):3186-93. PubMed ID: 18071314
    [Abstract] [Full Text] [Related]

  • 17. Alcohol promotes mammary tumor development via the estrogen pathway in estrogen receptor alpha-negative HER2/neu mice.
    Wong AW, Dunlap SM, Holcomb VB, Nunez NP.
    Alcohol Clin Exp Res; 2012 Apr 15; 36(4):577-87. PubMed ID: 21981381
    [Abstract] [Full Text] [Related]

  • 18. Aromatase overexpression and breast hyperplasia, an in vivo model--continued overexpression of aromatase is sufficient to maintain hyperplasia without circulating estrogens, and aromatase inhibitors abrogate these preneoplastic changes in mammary glands.
    Tekmal RR, Kirma N, Gill K, Fowler K.
    Endocr Relat Cancer; 1999 Jun 15; 6(2):307-14. PubMed ID: 10731124
    [Abstract] [Full Text] [Related]

  • 19. Catechol estrogen metabolites and conjugates in mammary tumors and hyperplastic tissue from estrogen receptor-alpha knock-out (ERKO)/Wnt-1 mice: implications for initiation of mammary tumors.
    Devanesan P, Santen RJ, Bocchinfuso WP, Korach KS, Rogan EG, Cavalieri E.
    Carcinogenesis; 2001 Sep 15; 22(9):1573-6. PubMed ID: 11532882
    [Abstract] [Full Text] [Related]

  • 20. Developmental stage determines estrogen receptor alpha expression and non-genomic mechanisms that control IGF-1 signaling and mammary proliferation in mice.
    Tian J, Berton TR, Shirley SH, Lambertz I, Gimenez-Conti IB, DiGiovanni J, Korach KS, Conti CJ, Fuchs-Young R.
    J Clin Invest; 2012 Jan 15; 122(1):192-204. PubMed ID: 22182837
    [Abstract] [Full Text] [Related]

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