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Journal Abstract Search
130 related items for PubMed ID: 15956785
21. An iminium ion metabolite hampers the production of the pharmacologically active metabolite of a multikinase inhibitor KW-2449 in primates: irreversible inhibition of aldehyde oxidase and covalent binding with endogenous proteins. Hosogi J, Ohashi R, Maeda H, Fujita K, Ushiki J, Kuwabara T, Yamamoto Y, Imamura T. Biopharm Drug Dispos; 2018 Mar; 39(3):164-174. PubMed ID: 29451686 [Abstract] [Full Text] [Related]
22. The role of aldehyde oxidase and xanthine oxidase in the biotransformation of a novel negative allosteric modulator of metabotropic glutamate receptor subtype 5. Morrison RD, Blobaum AL, Byers FW, Santomango TS, Bridges TM, Stec D, Brewer KA, Sanchez-Ponce R, Corlew MM, Rush R, Felts AS, Manka J, Bates BS, Venable DF, Rodriguez AL, Jones CK, Niswender CM, Conn PJ, Lindsley CW, Emmitte KA, Daniels JS. Drug Metab Dispos; 2012 Sep; 40(9):1834-45. PubMed ID: 22711749 [Abstract] [Full Text] [Related]
25. Inhibitory effects of Ruta graveolens L. extract on guinea pig liver aldehyde oxidase. Pirouzpanah S, Rashidi MR, Delazar A, Razavieh SV, Hamidi A. Chem Pharm Bull (Tokyo); 2006 Jan; 54(1):9-13. PubMed ID: 16394541 [Abstract] [Full Text] [Related]
26. A novel ring oxidation of 4- or 5-substituted 2H-oxazole to corresponding 2-oxazolone catalyzed by cytosolic aldehyde oxidase. Arora VK, Philip T, Huang S, Shu YZ. Drug Metab Dispos; 2012 Sep; 40(9):1668-76. PubMed ID: 22621803 [Abstract] [Full Text] [Related]
28. In Vitro Metabolism by Aldehyde Oxidase Leads to Poor Pharmacokinetic Profile in Rats for c-Met Inhibitor MET401. Zhang JW, Deng HB, Zhang CY, Dai JQ, Li Q, Zheng QG, Wan HX, Yu HP, He F, Xu YC, Zhao S, Zhang JYJ. Eur J Drug Metab Pharmacokinet; 2019 Oct; 44(5):669-680. PubMed ID: 31030415 [Abstract] [Full Text] [Related]
29. Involvement of molybdenum hydroxylases in reductive metabolism of nitro polycyclic aromatic hydrocarbons in mammalian skin. Ueda O, Sugihara K, Ohta S, Kitamura S. Drug Metab Dispos; 2005 Sep; 33(9):1312-8. PubMed ID: 15932950 [Abstract] [Full Text] [Related]