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99 related items for PubMed ID: 15957173

  • 1. Activating mutations in the extracellular domain of the melanoma inducing receptor Xmrk are tumorigenic in vivo.
    Winnemoeller D, Wellbrock C, Schartl M.
    Int J Cancer; 2005 Dec 10; 117(5):723-9. PubMed ID: 15957173
    [Abstract] [Full Text] [Related]

  • 2. Activation of the Xmrk proto-oncogene of Xiphophorus by overexpression and mutational alterations.
    Dimitrijevic N, Winkler C, Wellbrock C, Gómez A, Duschl J, Altschmied J, Schartl M.
    Oncogene; 1998 Apr 02; 16(13):1681-90. PubMed ID: 9582016
    [Abstract] [Full Text] [Related]

  • 3. Expression regulation triggers oncogenicity of xmrk alleles in the Xiphophorus melanoma system.
    Regneri J, Schartl M.
    Comp Biochem Physiol C Toxicol Pharmacol; 2012 Jan 02; 155(1):71-80. PubMed ID: 21527356
    [Abstract] [Full Text] [Related]

  • 4. Ligand-independent dimerization and activation of the oncogenic Xmrk receptor by two mutations in the extracellular domain.
    Gómez A, Wellbrock C, Gutbrod H, Dimitrijevic N, Schartl M.
    J Biol Chem; 2001 Feb 02; 276(5):3333-40. PubMed ID: 11038352
    [Abstract] [Full Text] [Related]

  • 5. Ligand-dependent tumor induction in medakafish embryos by a Xmrk receptor tyrosine kinase transgene.
    Winkler C, Wittbrodt J, Lammers R, Ullrich A, Schartl M.
    Oncogene; 1994 Jun 02; 9(6):1517-25. PubMed ID: 8183545
    [Abstract] [Full Text] [Related]

  • 6. PI3-kinase is involved in mitogenic signaling by the oncogenic receptor tyrosine kinase Xiphophorus melanoma receptor kinase in fish melanoma.
    Wellbrock C, Fischer P, Schartl M.
    Exp Cell Res; 1999 Sep 15; 251(2):340-9. PubMed ID: 10471319
    [Abstract] [Full Text] [Related]

  • 7. Genetic, biochemical and evolutionary facets of Xmrk-induced melanoma formation in the fish Xiphophorus.
    Meierjohann S, Schartl M, Volff JN.
    Comp Biochem Physiol C Toxicol Pharmacol; 2004 Jul 15; 138(3):281-9. PubMed ID: 15533786
    [Abstract] [Full Text] [Related]

  • 8. Association between the melanoma-inducing receptor tyrosine kinase Xmrk and src family tyrosine kinases in Xiphophorus.
    Wellbrock C, Lammers R, Ullrich A, Schartl M.
    Oncogene; 1995 Jun 01; 10(11):2135-43. PubMed ID: 7540277
    [Abstract] [Full Text] [Related]

  • 9. Transcriptional control analyses of the Xiphophorus melanoma oncogene.
    Regneri J, Volff JN, Schartl M.
    Comp Biochem Physiol C Toxicol Pharmacol; 2015 Dec 01; 178():116-127. PubMed ID: 26348392
    [Abstract] [Full Text] [Related]

  • 10. Signal transduction by the oncogenic receptor tyrosine kinase Xmrk in melanoma formation of Xiphophorus.
    Wellbrock C, Gómez A, Schartl M.
    Pigment Cell Res; 1997 Dec 01; 10(1-2):34-40. PubMed ID: 9170160
    [Abstract] [Full Text] [Related]

  • 11. Signalling by the oncogenic receptor tyrosine kinase Xmrk leads to activation of STAT5 in Xiphophorus melanoma.
    Wellbrock C, Geissinger E, Gómez A, Fischer P, Friedrich K, Schartl M.
    Oncogene; 1998 Jun 11; 16(23):3047-56. PubMed ID: 9662338
    [Abstract] [Full Text] [Related]

  • 12. Differences in transcription and promoters of Xmrk-1 and Xmrk-2 genes suggest a role for Xmrk-2 in pigment pattern development in the platyfish, Xiphophorus maculatus.
    Woolcock BW, Schmidt BM, Kallman KD, Vielkind JR.
    Cell Growth Differ; 1994 Jun 11; 5(6):575-83. PubMed ID: 7522032
    [Abstract] [Full Text] [Related]

  • 13. A mutated EGFR is sufficient to induce malignant melanoma with genetic background-dependent histopathologies.
    Schartl M, Wilde B, Laisney JA, Taniguchi Y, Takeda S, Meierjohann S.
    J Invest Dermatol; 2010 Jan 11; 130(1):249-58. PubMed ID: 19609310
    [Abstract] [Full Text] [Related]

  • 14. Melanoma loss-of-function mutants in Xiphophorus caused by Xmrk-oncogene deletion and gene disruption by a transposable element.
    Schartl M, Hornung U, Gutbrod H, Volff JN, Wittbrodt J.
    Genetics; 1999 Nov 11; 153(3):1385-94. PubMed ID: 10545466
    [Abstract] [Full Text] [Related]

  • 15. A structural model of the extracellular domain of the oncogenic EGFR variant Xmrk.
    Meierjohann S, Mueller T, Schartl M, Buehner M.
    Zebrafish; 2006 Nov 11; 3(3):359-69. PubMed ID: 18377216
    [Abstract] [Full Text] [Related]

  • 16. Receptor tyrosine kinase Xmrk mediates proliferation in Xiphophorus melanoma cells.
    Wellbrock C, Fischer P, Schartl M.
    Int J Cancer; 1998 May 04; 76(3):437-42. PubMed ID: 9579584
    [Abstract] [Full Text] [Related]

  • 17. The Xmrk receptor tyrosine kinase is activated in Xiphophorus malignant melanoma.
    Wittbrodt J, Lammers R, Malitschek B, Ullrich A, Schartl M.
    EMBO J; 1992 Nov 04; 11(11):4239-46. PubMed ID: 1327761
    [Abstract] [Full Text] [Related]

  • 18. Intragenic sex-chromosomal crossovers of Xmrk oncogene alleles affect pigment pattern formation and the severity of melanoma in Xiphophorus.
    Gutbrod H, Schartl M.
    Genetics; 1999 Feb 04; 151(2):773-83. PubMed ID: 9927468
    [Abstract] [Full Text] [Related]

  • 19. Activation of phosphatidylinositol 3-kinase by a complex of p59fyn and the receptor tyrosine kinase Xmrk is involved in malignant transformation of pigment cells.
    Wellbrock C, Schartl M.
    Eur J Biochem; 2000 Jun 04; 267(12):3513-22. PubMed ID: 10848967
    [Abstract] [Full Text] [Related]

  • 20. Transcriptional background effects on a tumor driver gene in different pigment cell types of medaka.
    Abdulsahib S, Boswell W, Boswell M, Savage M, Schartl M, Lu Y.
    J Exp Zool B Mol Dev Evol; 2024 May 04; 342(3):252-259. PubMed ID: 37877158
    [Abstract] [Full Text] [Related]


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