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210 related items for PubMed ID: 15961393

  • 1. Tyrosine phosphorylation regulates the proteolytic activation of protein kinase Cdelta in dopaminergic neuronal cells.
    Kaul S, Anantharam V, Yang Y, Choi CJ, Kanthasamy A, Kanthasamy AG.
    J Biol Chem; 2005 Aug 05; 280(31):28721-30. PubMed ID: 15961393
    [Abstract] [Full Text] [Related]

  • 2. Environmental neurotoxic pesticide dieldrin activates a non receptor tyrosine kinase to promote PKCδ-mediated dopaminergic apoptosis in a dopaminergic neuronal cell model.
    Saminathan H, Asaithambi A, Anantharam V, Kanthasamy AG, Kanthasamy A.
    Neurotoxicology; 2011 Oct 05; 32(5):567-77. PubMed ID: 21801747
    [Abstract] [Full Text] [Related]

  • 3. Dieldrin induces apoptosis by promoting caspase-3-dependent proteolytic cleavage of protein kinase Cdelta in dopaminergic cells: relevance to oxidative stress and dopaminergic degeneration.
    Kitazawa M, Anantharam V, Kanthasamy AG.
    Neuroscience; 2003 Oct 05; 119(4):945-64. PubMed ID: 12831855
    [Abstract] [Full Text] [Related]

  • 4. Blockade of PKCdelta proteolytic activation by loss of function mutants rescues mesencephalic dopaminergic neurons from methylcyclopentadienyl manganese tricarbonyl (MMT)-induced apoptotic cell death.
    Anantharam V, Kitazawa M, Latchoumycandane C, Kanthasamy A, Kanthasamy AG.
    Ann N Y Acad Sci; 2004 Dec 05; 1035():271-89. PubMed ID: 15681813
    [Abstract] [Full Text] [Related]

  • 5. A novel peptide inhibitor targeted to caspase-3 cleavage site of a proapoptotic kinase protein kinase C delta (PKCdelta) protects against dopaminergic neuronal degeneration in Parkinson's disease models.
    Kanthasamy AG, Anantharam V, Zhang D, Latchoumycandane C, Jin H, Kaul S, Kanthasamy A.
    Free Radic Biol Med; 2006 Nov 15; 41(10):1578-89. PubMed ID: 17045926
    [Abstract] [Full Text] [Related]

  • 6. Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl.
    Anantharam V, Kitazawa M, Wagner J, Kaul S, Kanthasamy AG.
    J Neurosci; 2002 Mar 01; 22(5):1738-51. PubMed ID: 11880503
    [Abstract] [Full Text] [Related]

  • 7. Protein kinase Cdelta is a key downstream mediator of manganese-induced apoptosis in dopaminergic neuronal cells.
    Latchoumycandane C, Anantharam V, Kitazawa M, Yang Y, Kanthasamy A, Kanthasamy AG.
    J Pharmacol Exp Ther; 2005 Apr 01; 313(1):46-55. PubMed ID: 15608081
    [Abstract] [Full Text] [Related]

  • 8. Caspase-3 dependent proteolytic activation of protein kinase C delta mediates and regulates 1-methyl-4-phenylpyridinium (MPP+)-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration.
    Kaul S, Kanthasamy A, Kitazawa M, Anantharam V, Kanthasamy AG.
    Eur J Neurosci; 2003 Sep 01; 18(6):1387-401. PubMed ID: 14511319
    [Abstract] [Full Text] [Related]

  • 9. Vanadium induces dopaminergic neurotoxicity via protein kinase Cdelta dependent oxidative signaling mechanisms: relevance to etiopathogenesis of Parkinson's disease.
    Afeseh Ngwa H, Kanthasamy A, Anantharam V, Song C, Witte T, Houk R, Kanthasamy AG.
    Toxicol Appl Pharmacol; 2009 Oct 15; 240(2):273-85. PubMed ID: 19646462
    [Abstract] [Full Text] [Related]

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  • 11. Dopaminergic neurotoxicant 6-OHDA induces oxidative damage through proteolytic activation of PKCδ in cell culture and animal models of Parkinson's disease.
    Latchoumycandane C, Anantharam V, Jin H, Kanthasamy A, Kanthasamy A.
    Toxicol Appl Pharmacol; 2011 Nov 01; 256(3):314-23. PubMed ID: 21846476
    [Abstract] [Full Text] [Related]

  • 12. Chronic low-dose oxidative stress induces caspase-3-dependent PKCdelta proteolytic activation and apoptosis in a cell culture model of dopaminergic neurodegeneration.
    Carvour M, Song C, Kaul S, Anantharam V, Kanthasamy A, Kanthasamy A.
    Ann N Y Acad Sci; 2008 Oct 01; 1139():197-205. PubMed ID: 18991865
    [Abstract] [Full Text] [Related]

  • 13. Suppression of caspase-3-dependent proteolytic activation of protein kinase C delta by small interfering RNA prevents MPP+-induced dopaminergic degeneration.
    Yang Y, Kaul S, Zhang D, Anantharam V, Kanthasamy AG.
    Mol Cell Neurosci; 2004 Mar 01; 25(3):406-21. PubMed ID: 15033169
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  • 15. Microarray analysis of oxidative stress regulated genes in mesencephalic dopaminergic neuronal cells: relevance to oxidative damage in Parkinson's disease.
    Anantharam V, Lehrmann E, Kanthasamy A, Yang Y, Banerjee P, Becker KG, Freed WJ, Kanthasamy AG.
    Neurochem Int; 2007 May 01; 50(6):834-47. PubMed ID: 17397968
    [Abstract] [Full Text] [Related]

  • 16. Activation of protein kinase C delta by proteolytic cleavage contributes to manganese-induced apoptosis in dopaminergic cells: protective role of Bcl-2.
    Kitazawa M, Anantharam V, Yang Y, Hirata Y, Kanthasamy A, Kanthasamy AG.
    Biochem Pharmacol; 2005 Jan 01; 69(1):133-46. PubMed ID: 15588722
    [Abstract] [Full Text] [Related]

  • 17. Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parkinson's disease.
    Kanthasamy AG, Kitazawa M, Yang Y, Anantharam V, Kanthasamy A.
    Mol Brain; 2008 Oct 22; 1():12. PubMed ID: 18945348
    [Abstract] [Full Text] [Related]

  • 18. Proteolytic activation of proapoptotic kinase protein kinase Cδ by tumor necrosis factor α death receptor signaling in dopaminergic neurons during neuroinflammation.
    Gordon R, Anantharam V, Kanthasamy AG, Kanthasamy A.
    J Neuroinflammation; 2012 Apr 27; 9():82. PubMed ID: 22540228
    [Abstract] [Full Text] [Related]

  • 19. Tyrosine phosphorylation of protein kinase Cdelta is essential for its apoptotic effect in response to etoposide.
    Blass M, Kronfeld I, Kazimirsky G, Blumberg PM, Brodie C.
    Mol Cell Biol; 2002 Jan 27; 22(1):182-95. PubMed ID: 11739733
    [Abstract] [Full Text] [Related]

  • 20. Pharmacological inhibition of neuronal NADPH oxidase protects against 1-methyl-4-phenylpyridinium (MPP+)-induced oxidative stress and apoptosis in mesencephalic dopaminergic neuronal cells.
    Anantharam V, Kaul S, Song C, Kanthasamy A, Kanthasamy AG.
    Neurotoxicology; 2007 Sep 27; 28(5):988-97. PubMed ID: 17904225
    [Abstract] [Full Text] [Related]


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