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138 related items for PubMed ID: 15963462

  • 1. Phosphorylation and binding partner analysis of the TSC1-TSC2 complex.
    Nellist M, Burgers PC, van den Ouweland AM, Halley DJ, Luider TM.
    Biochem Biophys Res Commun; 2005 Aug 05; 333(3):818-26. PubMed ID: 15963462
    [Abstract] [Full Text] [Related]

  • 2. The mTOR/S6K signalling pathway: the role of the TSC1/2 tumour suppressor complex and the proto-oncogene Rheb.
    Nobukini T, Thomas G.
    Novartis Found Symp; 2004 Aug 05; 262():148-54; discussion 154-9, 265-8. PubMed ID: 15562827
    [Abstract] [Full Text] [Related]

  • 3. Tuberous sclerosis: a GAP at the crossroads of multiple signaling pathways.
    Kwiatkowski DJ, Manning BD.
    Hum Mol Genet; 2005 Oct 15; 14 Spec No. 2():R251-8. PubMed ID: 16244323
    [Abstract] [Full Text] [Related]

  • 4. Analysis of 65 tuberous sclerosis complex (TSC) patients by TSC2 DGGE, TSC1/TSC2 MLPA, and TSC1 long-range PCR sequencing, and report of 28 novel mutations.
    Rendtorff ND, Bjerregaard B, Frödin M, Kjaergaard S, Hove H, Skovby F, Brøndum-Nielsen K, Schwartz M, Danish Tuberous Sclerosis Group.
    Hum Mutat; 2005 Oct 15; 26(4):374-83. PubMed ID: 16114042
    [Abstract] [Full Text] [Related]

  • 5. Measurements of TSC2 GAP activity toward Rheb.
    Li Y, Inoki K, Vikis H, Guan KL.
    Methods Enzymol; 2006 Oct 15; 407():46-54. PubMed ID: 16757313
    [Abstract] [Full Text] [Related]

  • 6. Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins.
    Zhang Y, Gao X, Saucedo LJ, Ru B, Edgar BA, Pan D.
    Nat Cell Biol; 2003 Jun 15; 5(6):578-81. PubMed ID: 12771962
    [Abstract] [Full Text] [Related]

  • 7. Tuberous sclerosis complex: linking growth and energy signaling pathways with human disease.
    Astrinidis A, Henske EP.
    Oncogene; 2005 Nov 14; 24(50):7475-81. PubMed ID: 16288294
    [Abstract] [Full Text] [Related]

  • 8. The cellular response to ectopic overexpression of the tuberous sclerosis genes, TSC1 and TSC2: a proteomic approach.
    Hengstschläger M, Rosner M, Fountoulakis M, Lubec G.
    Int J Oncol; 2005 Sep 14; 27(3):831-8. PubMed ID: 16077935
    [Abstract] [Full Text] [Related]

  • 9. Analysis of both TSC1 and TSC2 for germline mutations in 126 unrelated patients with tuberous sclerosis.
    Niida Y, Lawrence-Smith N, Banwell A, Hammer E, Lewis J, Beauchamp RL, Sims K, Ramesh V, Ozelius L.
    Hum Mutat; 1999 Sep 14; 14(5):412-22. PubMed ID: 10533067
    [Abstract] [Full Text] [Related]

  • 10. Heterozygosity for the tuberous sclerosis complex (TSC) gene products results in increased astrocyte numbers and decreased p27-Kip1 expression in TSC2+/- cells.
    Uhlmann EJ, Apicelli AJ, Baldwin RL, Burke SP, Bajenaru ML, Onda H, Kwiatkowski D, Gutmann DH.
    Oncogene; 2002 Jun 06; 21(25):4050-9. PubMed ID: 12037687
    [Abstract] [Full Text] [Related]

  • 11. Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling.
    Gao X, Zhang Y, Arrazola P, Hino O, Kobayashi T, Yeung RS, Ru B, Pan D.
    Nat Cell Biol; 2002 Sep 06; 4(9):699-704. PubMed ID: 12172555
    [Abstract] [Full Text] [Related]

  • 12. Proteins interacting with the tuberous sclerosis gene products.
    Rosner M, Freilinger A, Hengstschläger M.
    Amino Acids; 2004 Oct 06; 27(2):119-28. PubMed ID: 15351877
    [Abstract] [Full Text] [Related]

  • 13. Mutation and polymorphism analysis of TSC1 and TSC2 genes in Indian patients with tuberous sclerosis complex.
    Ali M, Girimaji SC, Markandaya M, Shukla AK, Sacchidanand S, Kumar A.
    Acta Neurol Scand; 2005 Jan 06; 111(1):54-63. PubMed ID: 15595939
    [Abstract] [Full Text] [Related]

  • 14. Loss of Tsc1 or Tsc2 induces vascular endothelial growth factor production through mammalian target of rapamycin.
    El-Hashemite N, Walker V, Zhang H, Kwiatkowski DJ.
    Cancer Res; 2003 Sep 01; 63(17):5173-7. PubMed ID: 14500340
    [Abstract] [Full Text] [Related]

  • 15. Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis.
    Ma L, Chen Z, Erdjument-Bromage H, Tempst P, Pandolfi PP.
    Cell; 2005 Apr 22; 121(2):179-93. PubMed ID: 15851026
    [Abstract] [Full Text] [Related]

  • 16. Mutational analysis of TSC1 and TSC2 in Korean patients with tuberous sclerosis complex.
    Choi JE, Chae JH, Hwang YS, Kim KJ.
    Brain Dev; 2006 Aug 22; 28(7):440-6. PubMed ID: 16554133
    [Abstract] [Full Text] [Related]

  • 17. The tuberous sclerosis genes, TSC1 and TSC2, trigger different gene expression responses.
    Rosner M, Freilinger A, Lubec G, Hengstschläger M.
    Int J Oncol; 2005 Nov 22; 27(5):1411-24. PubMed ID: 16211238
    [Abstract] [Full Text] [Related]

  • 18. Distinct effects of single amino-acid changes to tuberin on the function of the tuberin-hamartin complex.
    Nellist M, Sancak O, Goedbloed MA, Rohe C, van Netten D, Mayer K, Tucker-Williams A, van den Ouweland AM, Halley DJ.
    Eur J Hum Genet; 2005 Jan 22; 13(1):59-68. PubMed ID: 15483652
    [Abstract] [Full Text] [Related]

  • 19. Analysis of TSC2 stop codon variants found in tuberous sclerosis patients.
    Goedbloed MA, Nellist M, Verhaaf B, Reuser AJ, Lindhout D, Sunde L, Verhoef S, Halley DJ, van den Ouweland AM.
    Eur J Hum Genet; 2001 Nov 22; 9(11):823-8. PubMed ID: 11781698
    [Abstract] [Full Text] [Related]

  • 20. Mutational analysis of the TSC1 and TSC2 genes in a diagnostic setting: genotype--phenotype correlations and comparison of diagnostic DNA techniques in Tuberous Sclerosis Complex.
    Sancak O, Nellist M, Goedbloed M, Elfferich P, Wouters C, Maat-Kievit A, Zonnenberg B, Verhoef S, Halley D, van den Ouweland A.
    Eur J Hum Genet; 2005 Jun 22; 13(6):731-41. PubMed ID: 15798777
    [Abstract] [Full Text] [Related]

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