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147 related items for PubMed ID: 15974585

  • 1. 2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors.
    Allegretti M, Bertini R, Cesta MC, Bizzarri C, Di Bitondo R, Di Cioccio V, Galliera E, Berdini V, Topai A, Zampella G, Russo V, Di Bello N, Nano G, Nicolini L, Locati M, Fantucci P, Florio S, Colotta F.
    J Med Chem; 2005 Jun 30; 48(13):4312-31. PubMed ID: 15974585
    [Abstract] [Full Text] [Related]

  • 2. Design of noncompetitive interleukin-8 inhibitors acting on CXCR1 and CXCR2.
    Moriconi A, Cesta MC, Cervellera MN, Aramini A, Coniglio S, Colagioia S, Beccari AR, Bizzarri C, Cavicchia MR, Locati M, Galliera E, Di Benedetto P, Vigilante P, Bertini R, Allegretti M.
    J Med Chem; 2007 Aug 23; 50(17):3984-4002. PubMed ID: 17665889
    [Abstract] [Full Text] [Related]

  • 3. Rabbit neutrophil chemotactic protein (NCP) activates both CXCR1 and CXCR2 and is the functional homologue for human CXCL6.
    Catusse J, Struyf S, Wuyts A, Weyler M, Loos T, Gijsbers K, Gouwy M, Proost P, Van Damme J.
    Biochem Pharmacol; 2004 Nov 15; 68(10):1947-55. PubMed ID: 15476666
    [Abstract] [Full Text] [Related]

  • 4. Towards in situ tissue repair: human mesenchymal stem cells express chemokine receptors CXCR1, CXCR2 and CCR2, and migrate upon stimulation with CXCL8 but not CCL2.
    Ringe J, Strassburg S, Neumann K, Endres M, Notter M, Burmester GR, Kaps C, Sittinger M.
    J Cell Biochem; 2007 May 01; 101(1):135-46. PubMed ID: 17295203
    [Abstract] [Full Text] [Related]

  • 5. ELR+ CXC chemokines and their receptors (CXC chemokine receptor 1 and CXC chemokine receptor 2) as new therapeutic targets.
    Bizzarri C, Beccari AR, Bertini R, Cavicchia MR, Giorgini S, Allegretti M.
    Pharmacol Ther; 2006 Oct 01; 112(1):139-49. PubMed ID: 16720046
    [Abstract] [Full Text] [Related]

  • 6. Synergy between proinflammatory ligands of G protein-coupled receptors in neutrophil activation and migration.
    Gouwy M, Struyf S, Catusse J, Proost P, Van Damme J.
    J Leukoc Biol; 2004 Jul 01; 76(1):185-94. PubMed ID: 15075362
    [Abstract] [Full Text] [Related]

  • 7. Pharmacological characterization of Sch527123, a potent allosteric CXCR1/CXCR2 antagonist.
    Gonsiorek W, Fan X, Hesk D, Fossetta J, Qiu H, Jakway J, Billah M, Dwyer M, Chao J, Deno G, Taveras A, Lundell DJ, Hipkin RW.
    J Pharmacol Exp Ther; 2007 Aug 01; 322(2):477-85. PubMed ID: 17496166
    [Abstract] [Full Text] [Related]

  • 8. Identification of a putative intracellular allosteric antagonist binding-site in the CXC chemokine receptors 1 and 2.
    Nicholls DJ, Tomkinson NP, Wiley KE, Brammall A, Bowers L, Grahames C, Gaw A, Meghani P, Shelton P, Wright TJ, Mallinder PR.
    Mol Pharmacol; 2008 Nov 01; 74(5):1193-202. PubMed ID: 18676678
    [Abstract] [Full Text] [Related]

  • 9. Development of a systemically-active dual CXCR1/CXCR2 allosteric inhibitor and its efficacy in a model of transient cerebral ischemia in the rat.
    Garau A, Bertini R, Mosca M, Bizzarri C, Anacardio R, Triulzi S, Allegretti M, Ghezzi P, Villa P.
    Eur Cytokine Netw; 2006 Mar 01; 17(1):35-41. PubMed ID: 16613761
    [Abstract] [Full Text] [Related]

  • 10. Intracellular trafficking of human CXCR1 and CXCR2: regulation by receptor domains and actin-related kinases.
    Matityahu E, Feniger-Barish R, Meshel T, Zaslaver A, Ben-Baruch A.
    Eur J Immunol; 2002 Dec 01; 32(12):3525-35. PubMed ID: 12442335
    [Abstract] [Full Text] [Related]

  • 11. CXCL8-induced FAK phosphorylation via CXCR1 and CXCR2: cytoskeleton- and integrin-related mechanisms converge with FAK regulatory pathways in a receptor-specific manner.
    Cohen-Hillel E, Yron I, Meshel T, Soria G, Attal H, Ben-Baruch A.
    Cytokine; 2006 Jan 07; 33(1):1-16. PubMed ID: 16406804
    [Abstract] [Full Text] [Related]

  • 12. CXCL8((3-73))K11R/G31P antagonizes ligand binding to the neutrophil CXCR1 and CXCR2 receptors and cellular responses to CXCL8/IL-8.
    Li F, Zhang X, Gordon JR.
    Biochem Biophys Res Commun; 2002 May 10; 293(3):939-44. PubMed ID: 12051749
    [Abstract] [Full Text] [Related]

  • 13. Computational studies of CXCR1, the receptor of IL-8/CXCL8, using molecular dynamics and electrostatics.
    Huynh N, Mallik B, Zhang L, Martins-Green M, Morikis D.
    Biopolymers; 2008 Jan 10; 89(1):52-61. PubMed ID: 17876799
    [Abstract] [Full Text] [Related]

  • 14. Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury.
    Bertini R, Allegretti M, Bizzarri C, Moriconi A, Locati M, Zampella G, Cervellera MN, Di Cioccio V, Cesta MC, Galliera E, Martinez FO, Di Bitondo R, Troiani G, Sabbatini V, D'Anniballe G, Anacardio R, Cutrin JC, Cavalieri B, Mainiero F, Strippoli R, Villa P, Di Girolamo M, Martin F, Gentile M, Santoni A, Corda D, Poli G, Mantovani A, Ghezzi P, Colotta F.
    Proc Natl Acad Sci U S A; 2004 Aug 10; 101(32):11791-6. PubMed ID: 15282370
    [Abstract] [Full Text] [Related]

  • 15. The functional significance behind expressing two IL-8 receptor types on PMN.
    Stillie R, Farooq SM, Gordon JR, Stadnyk AW.
    J Leukoc Biol; 2009 Sep 10; 86(3):529-43. PubMed ID: 19564575
    [Abstract] [Full Text] [Related]

  • 16. CXC chemokine receptors on human oligodendrocytes: implications for multiple sclerosis.
    Omari KM, John GR, Sealfon SC, Raine CS.
    Brain; 2005 May 10; 128(Pt 5):1003-15. PubMed ID: 15774504
    [Abstract] [Full Text] [Related]

  • 17. Cloning and characterization of mouse homolog of the CXC chemokine receptor CXCR1.
    Fu W, Zhang Y, Zhang J, Chen WF.
    Cytokine; 2005 Jul 07; 31(1):9-17. PubMed ID: 15967374
    [Abstract] [Full Text] [Related]

  • 18. Structure-Activity Relationship of novel phenylacetic CXCR1 inhibitors.
    Sablone MR, Cesta MC, Moriconi A, Aramini A, Bizzarri C, Di Giacinto C, Di Bitondo R, Gloaguen I, Aschi M, Crucianelli M, Bertini R, Allegretti M.
    Bioorg Med Chem Lett; 2009 Aug 01; 19(15):4026-30. PubMed ID: 19560921
    [Abstract] [Full Text] [Related]

  • 19. cCXCR1 is a receptor for cIL-8 (9E3/cCAF) and its N- and C-terminal peptides and is also activated by hIL-8 (CXCL8).
    Li QJ, Yao M, Dueck M, Feugate JE, Parpura V, Martins-Green M.
    J Leukoc Biol; 2005 Mar 01; 77(3):421-31. PubMed ID: 15576419
    [Abstract] [Full Text] [Related]

  • 20. Probing the role of CXC motif in chemokine CXCL8 for high affinity binding and activation of CXCR1 and CXCR2 receptors.
    Joseph PR, Sarmiento JM, Mishra AK, Das ST, Garofalo RP, Navarro J, Rajarathnam K.
    J Biol Chem; 2010 Sep 17; 285(38):29262-9. PubMed ID: 20630874
    [Abstract] [Full Text] [Related]

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