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189 related items for PubMed ID: 15976219

  • 1. R (+) etomidate and the photoactivable R (+) azietomidate have comparable anesthetic activity in wild-type mice and comparably decreased activity in mice with a N265M point mutation in the gamma-aminobutyric acid receptor beta3 subunit.
    Liao M, Sonner JM, Husain SS, Miller KW, Jurd R, Rudolph U, Eger EI.
    Anesth Analg; 2005 Jul; 101(1):131-5, table of contents. PubMed ID: 15976219
    [Abstract] [Full Text] [Related]

  • 2. Distinct actions of etomidate and propofol at beta3-containing gamma-aminobutyric acid type A receptors.
    Drexler B, Jurd R, Rudolph U, Antkowiak B.
    Neuropharmacology; 2009 Sep; 57(4):446-55. PubMed ID: 19555700
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  • 3. Activity patterns in the prefrontal cortex and hippocampus during and after awakening from etomidate anesthesia.
    Butovas S, Rudolph U, Jurd R, Schwarz C, Antkowiak B.
    Anesthesiology; 2010 Jul; 113(1):48-57. PubMed ID: 20508498
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  • 4. 2-(3-Methyl-3H-diaziren-3-yl)ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate: a derivative of the stereoselective general anesthetic etomidate for photolabeling ligand-gated ion channels.
    Husain SS, Ziebell MR, Ruesch D, Hong F, Arevalo E, Kosterlitz JA, Olsen RW, Forman SA, Cohen JB, Miller KW.
    J Med Chem; 2003 Mar 27; 46(7):1257-65. PubMed ID: 12646036
    [Abstract] [Full Text] [Related]

  • 5. Contrasting Effects of the γ-Aminobutyric Acid Type A Receptor β3 Subunit N265M Mutation on Loss of Righting Reflexes Induced by Etomidate and the Novel Anesthetic Barbiturate R-mTFD-MPAB.
    Amlong CA, Perkins MG, Houle TT, Miller KW, Pearce RA.
    Anesth Analg; 2016 Nov 27; 123(5):1241-1246. PubMed ID: 27331778
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  • 10. Etomidate and propofol-hyposensitive GABAA receptor beta3(N265M) mice show little changes in acute alcohol sensitivity but enhanced tolerance and withdrawal.
    Sanchis-Segura C, Cline B, Jurd R, Rudolph U, Spanagel R.
    Neurosci Lett; 2007 Apr 18; 416(3):275-8. PubMed ID: 17350761
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  • 11. Distinct molecular targets for the central respiratory and cardiac actions of the general anesthetics etomidate and propofol.
    Zeller A, Arras M, Lazaris A, Jurd R, Rudolph U.
    FASEB J; 2005 Oct 18; 19(12):1677-9. PubMed ID: 16046472
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  • 12. A conserved tyrosine in the beta2 subunit M4 segment is a determinant of gamma-aminobutyric acid type A receptor sensitivity to propofol.
    Richardson JE, Garcia PS, O'Toole KK, Derry JM, Bell SV, Jenkins A.
    Anesthesiology; 2007 Sep 18; 107(3):412-8. PubMed ID: 17721243
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  • 13. Etomidate blocks LTP and impairs learning but does not enhance tonic inhibition in mice carrying the N265M point mutation in the beta3 subunit of the GABA(A) receptor.
    Zarnowska ED, Rodgers FC, Oh I, Rau V, Lor C, Laha KT, Jurd R, Rudolph U, Eger EI, Pearce RA.
    Neuropharmacology; 2015 Jun 18; 93():171-178. PubMed ID: 25680234
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  • 14. Stereoselective effects of etomidate optical isomers on gamma-aminobutyric acid type A receptors and animals.
    Tomlin SL, Jenkins A, Lieb WR, Franks NP.
    Anesthesiology; 1998 Mar 18; 88(3):708-17. PubMed ID: 9523815
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  • 15. Changes in Memory, Sedation, and Receptor Kinetics Imparted by the β2-N265M and β3-N265M GABAA Receptor Point Mutations.
    Abdulzahir A, Klein S, Lor C, Perkins MG, Frelka A, Pearce RA.
    Int J Mol Sci; 2023 Mar 15; 24(6):. PubMed ID: 36982709
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  • 16. Mapping general anesthetic binding site(s) in human α1β3 γ-aminobutyric acid type A receptors with [³H]TDBzl-etomidate, a photoreactive etomidate analogue.
    Chiara DC, Dostalova Z, Jayakar SS, Zhou X, Miller KW, Cohen JB.
    Biochemistry; 2012 Jan 31; 51(4):836-47. PubMed ID: 22243422
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  • 17. Isoflurane Potentiation of GABAA Receptors Is Reduced but Not Eliminated by the β3(N265M) Mutation.
    Lor C, Perouansky M, Pearce RA.
    Int J Mol Sci; 2020 Dec 15; 21(24):. PubMed ID: 33333797
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  • 18. GABA(A)-R alpha1 subunit knockin mutation leads to abnormal EEG and anesthetic-induced seizure-like activity in mice.
    Elsen FP, Liljelund P, Werner DF, Olsen RW, Homanics GE, Harrison NL.
    Brain Res; 2006 Mar 17; 1078(1):60-70. PubMed ID: 16490182
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  • 19. Analogues of etomidate: modifications around etomidate's chiral carbon and the impact on in vitro and in vivo pharmacology.
    Pejo E, Santer P, Jeffrey S, Gallin H, Husain SS, Raines DE.
    Anesthesiology; 2014 Aug 17; 121(2):290-301. PubMed ID: 24777068
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  • 20. Etomidate targets alpha5 gamma-aminobutyric acid subtype A receptors to regulate synaptic plasticity and memory blockade.
    Martin LJ, Oh GH, Orser BA.
    Anesthesiology; 2009 Nov 17; 111(5):1025-35. PubMed ID: 19809285
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