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435 related items for PubMed ID: 15978696

  • 1. Wild-type alpha-synuclein interacts with pro-apoptotic proteins PKCdelta and BAD to protect dopaminergic neuronal cells against MPP+-induced apoptotic cell death.
    Kaul S, Anantharam V, Kanthasamy A, Kanthasamy AG.
    Brain Res Mol Brain Res; 2005 Sep 13; 139(1):137-52. PubMed ID: 15978696
    [Abstract] [Full Text] [Related]

  • 2. Suppression of caspase-3-dependent proteolytic activation of protein kinase C delta by small interfering RNA prevents MPP+-induced dopaminergic degeneration.
    Yang Y, Kaul S, Zhang D, Anantharam V, Kanthasamy AG.
    Mol Cell Neurosci; 2004 Mar 13; 25(3):406-21. PubMed ID: 15033169
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  • 3. Dieldrin induces ubiquitin-proteasome dysfunction in alpha-synuclein overexpressing dopaminergic neuronal cells and enhances susceptibility to apoptotic cell death.
    Sun F, Anantharam V, Latchoumycandane C, Kanthasamy A, Kanthasamy AG.
    J Pharmacol Exp Ther; 2005 Oct 13; 315(1):69-79. PubMed ID: 15987830
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  • 4. Characterization of MPP(+)-induced cell death in a dopaminergic neuronal cell line: role of macromolecule synthesis, cytosolic calcium, caspase, and Bcl-2-related proteins.
    Choi WS, Canzoniero LM, Sensi SL, O'Malley KL, Gwag BJ, Sohn S, Kim JE, Oh TH, Lee EB, Oh YJ.
    Exp Neurol; 1999 Sep 13; 159(1):274-82. PubMed ID: 10486196
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  • 5. Inhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons.
    Alvira D, Tajes M, Verdaguer E, de Arriba SG, Allgaier C, Matute C, Trullas R, Jiménez A, Pallàs M, Camins A.
    Neuroscience; 2007 Apr 25; 146(1):350-65. PubMed ID: 17343987
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  • 6. Differential effects of overexpression of wild-type and mutant human alpha-synuclein on MPP+-induced neurotoxicity in PC12 cells.
    Qian JJ, Cheng YB, Yang YP, Mao CJ, Qin ZH, Li K, Liu CF.
    Neurosci Lett; 2008 Apr 18; 435(2):142-6. PubMed ID: 18342443
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  • 7. Blockade of PKCdelta proteolytic activation by loss of function mutants rescues mesencephalic dopaminergic neurons from methylcyclopentadienyl manganese tricarbonyl (MMT)-induced apoptotic cell death.
    Anantharam V, Kitazawa M, Latchoumycandane C, Kanthasamy A, Kanthasamy AG.
    Ann N Y Acad Sci; 2004 Dec 18; 1035():271-89. PubMed ID: 15681813
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  • 8. Protective effects of the antiparkinsonian drugs talipexole and pramipexole against 1-methyl-4-phenylpyridinium-induced apoptotic death in human neuroblastoma SH-SY5Y cells.
    Kitamura Y, Kosaka T, Kakimura JI, Matsuoka Y, Kohno Y, Nomura Y, Taniguchi T.
    Mol Pharmacol; 1998 Dec 18; 54(6):1046-54. PubMed ID: 9855633
    [Abstract] [Full Text] [Related]

  • 9. Rifampicin protects PC12 cells against MPP+-induced apoptosis and inhibits the expression of an alpha-Synuclein multimer.
    Xu J, Wei C, Xu C, Bennett MC, Zhang G, Li F, Tao E.
    Brain Res; 2007 Mar 30; 1139():220-5. PubMed ID: 17280646
    [Abstract] [Full Text] [Related]

  • 10. Dopamine-related and caspase-independent apoptosis in dopaminergic neurons induced by overexpression of human wild type or mutant alpha-synuclein.
    Zhou ZD, Yap BP, Gung AY, Leong SM, Ang ST, Lim TM.
    Exp Cell Res; 2006 Jan 15; 312(2):156-70. PubMed ID: 16297908
    [Abstract] [Full Text] [Related]

  • 11. A cell-permeable peptide inhibitor TAT-JBD reduces the MPP+-induced caspase-9 activation but does not prevent the dopaminergic degeneration in substantia nigra of rats.
    Pain S, Barrier L, Deguil J, Milin S, Piriou A, Fauconneau B, Page G.
    Toxicology; 2008 Jan 14; 243(1-2):124-37. PubMed ID: 18037221
    [Abstract] [Full Text] [Related]

  • 12. Caspase-3 dependent proteolytic activation of protein kinase C delta mediates and regulates 1-methyl-4-phenylpyridinium (MPP+)-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration.
    Kaul S, Kanthasamy A, Kitazawa M, Anantharam V, Kanthasamy AG.
    Eur J Neurosci; 2003 Sep 14; 18(6):1387-401. PubMed ID: 14511319
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  • 16. Comparison of the time courses of selective gene expression and dopaminergic depletion induced by MPP+ in MN9D cells.
    Wang J, Duhart HM, Xu Z, Patterson TA, Newport GD, Ali SF.
    Neurochem Int; 2008 May 14; 52(6):1037-43. PubMed ID: 18069091
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  • 17. Salvianic acid A protects human neuroblastoma SH-SY5Y cells against MPP+-induced cytotoxicity.
    Wang XJ, Xu JX.
    Neurosci Res; 2005 Feb 14; 51(2):129-38. PubMed ID: 15681030
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