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205 related items for PubMed ID: 15982636

  • 1. Interaction of Bcr/Abl with C3G, an exchange factor for the small GTPase Rap1, through the adapter protein Crkl.
    Cho YJ, Hemmeryckx B, Groffen J, Heisterkamp N.
    Biochem Biophys Res Commun; 2005 Aug 12; 333(4):1276-83. PubMed ID: 15982636
    [Abstract] [Full Text] [Related]

  • 2. Bcr/Abl P190 interaction with Spa-1, a GTPase activating protein for the small GTPase Rap1.
    Yi SJ, Lee HT, Groffen J, Heisterkamp N.
    Int J Mol Med; 2008 Oct 12; 22(4):453-8. PubMed ID: 18813851
    [Abstract] [Full Text] [Related]

  • 3. Crkl enhances leukemogenesis in BCR/ABL P190 transgenic mice.
    Hemmeryckx B, van Wijk A, Reichert A, Kaartinen V, de Jong R, Pattengale PK, Gonzalez-Gomez I, Groffen J, Heisterkamp N.
    Cancer Res; 2001 Feb 15; 61(4):1398-405. PubMed ID: 11245441
    [Abstract] [Full Text] [Related]

  • 4. Characterization of p87C3G, a novel, truncated C3G isoform that is overexpressed in chronic myeloid leukemia and interacts with Bcr-Abl.
    Gutiérrez-Berzal J, Castellano E, Martín-Encabo S, Gutiérrez-Cianca N, Hernández JM, Santos E, Guerrero C.
    Exp Cell Res; 2006 Apr 01; 312(6):938-48. PubMed ID: 16443220
    [Abstract] [Full Text] [Related]

  • 5. C3G is tyrosine-phosphorylated after integrin-mediated cell adhesion in normal but not in Bcr/Abl expressing cells.
    de Jong R, van Wijk A, Heisterkamp N, Groffen J.
    Oncogene; 1998 Nov 26; 17(21):2805-10. PubMed ID: 9840945
    [Abstract] [Full Text] [Related]

  • 6. Tyrosine phosphorylation of murine Crkl.
    de Jong R, Haataja L, Voncken JW, Heisterkamp N, Groffen J.
    Oncogene; 1995 Oct 19; 11(8):1469-74. PubMed ID: 7478571
    [Abstract] [Full Text] [Related]

  • 7. Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site.
    de Jong R, ten Hoeve J, Heisterkamp N, Groffen J.
    Oncogene; 1997 Feb 06; 14(5):507-13. PubMed ID: 9053848
    [Abstract] [Full Text] [Related]

  • 8. Cellular interactions of CRKL, and SH2-SH3 adaptor protein.
    ten Hoeve J, Kaartinen V, Fioretos T, Haataja L, Voncken JW, Heisterkamp N, Groffen J.
    Cancer Res; 1994 May 15; 54(10):2563-7. PubMed ID: 8168080
    [Abstract] [Full Text] [Related]

  • 9. BCR/ABL P190 transgenic mice develop leukemia in the absence of Crkl.
    Hemmeryckx B, Reichert A, Watanabe M, Kaartinen V, de Jong R, Pattengale PK, Groffen J, Heisterkamp N.
    Oncogene; 2002 May 09; 21(20):3225-31. PubMed ID: 12082638
    [Abstract] [Full Text] [Related]

  • 10. Anaplastic lymphoma kinase activates the small GTPase Rap1 via the Rap1-specific GEF C3G in both neuroblastoma and PC12 cells.
    Schönherr C, Yang HL, Vigny M, Palmer RH, Hallberg B.
    Oncogene; 2010 May 13; 29(19):2817-30. PubMed ID: 20190816
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of Grb2 and Crkl proteins results in growth inhibition of Philadelphia chromosome positive leukemic cells.
    Tari AM, Arlinghaus R, Lopez-Berestein G.
    Biochem Biophys Res Commun; 1997 Jun 18; 235(2):383-8. PubMed ID: 9199202
    [Abstract] [Full Text] [Related]

  • 12. Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis.
    Ohba Y, Ikuta K, Ogura A, Matsuda J, Mochizuki N, Nagashima K, Kurokawa K, Mayer BJ, Maki K, Miyazaki J, Matsuda M.
    EMBO J; 2001 Jul 02; 20(13):3333-41. PubMed ID: 11432821
    [Abstract] [Full Text] [Related]

  • 13. The WAVE2 complex regulates T cell receptor signaling to integrins via Abl- and CrkL-C3G-mediated activation of Rap1.
    Nolz JC, Nacusi LP, Segovis CM, Medeiros RB, Mitchell JS, Shimizu Y, Billadeau DD.
    J Cell Biol; 2008 Sep 22; 182(6):1231-44. PubMed ID: 18809728
    [Abstract] [Full Text] [Related]

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  • 17. Phosphorylation levels of BCR-ABL, CrkL, AKT and STAT5 in imatinib-resistant chronic myeloid leukemia cells implicate alternative pathway usage as a survival strategy.
    Jilani I, Kantarjian H, Gorre M, Cortes J, Ottmann O, Bhalla K, Giles FJ, Albitar M.
    Leuk Res; 2008 Apr 22; 32(4):643-9. PubMed ID: 17900686
    [Abstract] [Full Text] [Related]

  • 18. Engagement of the CrkL adaptor in interferon alpha signalling in BCR-ABL-expressing cells.
    Grumbach IM, Mayer IA, Uddin S, Lekmine F, Majchrzak B, Yamauchi H, Fujita S, Druker B, Fish EN, Platanias LC.
    Br J Haematol; 2001 Feb 22; 112(2):327-36. PubMed ID: 11167825
    [Abstract] [Full Text] [Related]

  • 19. p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene.
    Salgia R, Pisick E, Sattler M, Li JL, Uemura N, Wong WK, Burky SA, Hirai H, Chen LB, Griffin JD.
    J Biol Chem; 1996 Oct 11; 271(41):25198-203. PubMed ID: 8810278
    [Abstract] [Full Text] [Related]

  • 20. Role of SPA-1 in phenotypes of chronic myelogenous leukemia induced by BCR-ABL-expressing hematopoietic progenitors in a mouse model.
    Kometani K, Aoki M, Kawamata S, Shinozuka Y, Era T, Taniwaki M, Hattori M, Minato N.
    Cancer Res; 2006 Oct 15; 66(20):9967-76. PubMed ID: 17047059
    [Abstract] [Full Text] [Related]


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