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Journal Abstract Search
196 related items for PubMed ID: 15985503
1. Seeing through the mist: abundance versus percentage. Commentary on metabolites in safety testing. Smith DA, Obach RS. Drug Metab Dispos; 2005 Oct; 33(10):1409-17. PubMed ID: 15985503 [Abstract] [Full Text] [Related]
12. A regulatory perspective on issues and approaches in characterizing human metabolites. Davis-Bruno KL, Atrakchi A. Chem Res Toxicol; 2006 Dec; 19(12):1561-3. PubMed ID: 17173368 [Abstract] [Full Text] [Related]
14. Metabolites in safety testing: metabolite identification strategies in discovery and development. Nedderman AN. Biopharm Drug Dispos; 2009 May; 30(4):153-62. PubMed ID: 19544286 [Abstract] [Full Text] [Related]
15. Safety assessment of drug metabolites: implications of regulatory guidance and potential application of genetically engineered mouse models that express human P450s. Powley MW, Frederick CB, Sistare FD, DeGeorge JJ. Chem Res Toxicol; 2009 Feb; 22(2):257-62. PubMed ID: 19170595 [Abstract] [Full Text] [Related]
16. A perspective on the contribution of metabolites to drug-drug interaction potential: the need to consider both circulating levels and inhibition potency. Yu H, Tweedie D. Drug Metab Dispos; 2013 Mar; 41(3):536-40. PubMed ID: 23143892 [Abstract] [Full Text] [Related]
17. Introduction: Human metabolites in safety testing (MIST) issue. Guengerich FP. Chem Res Toxicol; 2009 Feb; 22(2):237-8. PubMed ID: 19216576 [No Abstract] [Full Text] [Related]