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212 related items for PubMed ID: 15994317

  • 1. The platelet-derived growth factor receptor-beta phosphorylates and activates G protein-coupled receptor kinase-2. A mechanism for feedback inhibition.
    Wu JH, Goswami R, Kim LK, Miller WE, Peppel K, Freedman NJ.
    J Biol Chem; 2005 Sep 02; 280(35):31027-35. PubMed ID: 15994317
    [Abstract] [Full Text] [Related]

  • 2. Phosphorylation of the platelet-derived growth factor receptor-beta by G protein-coupled receptor kinase-2 reduces receptor signaling and interaction with the Na(+)/H(+) exchanger regulatory factor.
    Hildreth KL, Wu JH, Barak LS, Exum ST, Kim LK, Peppel K, Freedman NJ.
    J Biol Chem; 2004 Oct 01; 279(40):41775-82. PubMed ID: 15271984
    [Abstract] [Full Text] [Related]

  • 3. Regulation of the platelet-derived growth factor receptor-beta by G protein-coupled receptor kinase-5 in vascular smooth muscle cells involves the phosphatase Shp2.
    Wu JH, Goswami R, Cai X, Exum ST, Huang X, Zhang L, Brian L, Premont RT, Peppel K, Freedman NJ.
    J Biol Chem; 2006 Dec 08; 281(49):37758-72. PubMed ID: 17018529
    [Abstract] [Full Text] [Related]

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  • 5. Phosphorylation of the platelet-derived growth factor receptor-beta and epidermal growth factor receptor by G protein-coupled receptor kinase-2. Mechanisms for selectivity of desensitization.
    Freedman NJ, Kim LK, Murray JP, Exum ST, Brian L, Wu JH, Peppel K.
    J Biol Chem; 2002 Dec 13; 277(50):48261-9. PubMed ID: 12381737
    [Abstract] [Full Text] [Related]

  • 6. Agonist-dependent phosphorylation of the G protein-coupled receptor kinase 2 (GRK2) by Src tyrosine kinase.
    Sarnago S, Elorza A, Mayor F.
    J Biol Chem; 1999 Nov 26; 274(48):34411-6. PubMed ID: 10567420
    [Abstract] [Full Text] [Related]

  • 7. Mutation of tyrosine residue 857 in the PDGF beta-receptor affects cell proliferation but not migration.
    Wardega P, Heldin CH, Lennartsson J.
    Cell Signal; 2010 Sep 26; 22(9):1363-8. PubMed ID: 20494825
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  • 9. Desensitization of beta2-adrenergic receptors with mutations of the proposed G protein-coupled receptor kinase phosphorylation sites.
    Seibold A, January BG, Friedman J, Hipkin RW, Clark RB.
    J Biol Chem; 1998 Mar 27; 273(13):7637-42. PubMed ID: 9516468
    [Abstract] [Full Text] [Related]

  • 10. Identification of the G protein-coupled receptor kinase phosphorylation sites in the human beta2-adrenergic receptor.
    Fredericks ZL, Pitcher JA, Lefkowitz RJ.
    J Biol Chem; 1996 Jun 07; 271(23):13796-803. PubMed ID: 8662852
    [Abstract] [Full Text] [Related]

  • 11. Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2.
    Carman CV, Parent JL, Day PW, Pronin AN, Sternweis PM, Wedegaertner PB, Gilman AG, Benovic JL, Kozasa T.
    J Biol Chem; 1999 Nov 26; 274(48):34483-92. PubMed ID: 10567430
    [Abstract] [Full Text] [Related]

  • 12. Platelet-derived growth factor receptor beta activates Abl2 via direct binding and phosphorylation.
    Wu K, Wu H, Lyu W, Kim Y, Furdui CM, Anderson KS, Koleske AJ.
    J Biol Chem; 2021 Jul 26; 297(1):100883. PubMed ID: 34144039
    [Abstract] [Full Text] [Related]

  • 13. c-Src is involved in regulating signal transmission from PDGFbeta receptor-GPCR(s) complexes in mammalian cells.
    Waters CM, Connell MC, Pyne S, Pyne NJ.
    Cell Signal; 2005 Feb 26; 17(2):263-77. PubMed ID: 15494217
    [Abstract] [Full Text] [Related]

  • 14. Receptor and G betagamma isoform-specific interactions with G protein-coupled receptor kinases.
    Daaka Y, Pitcher JA, Richardson M, Stoffel RH, Robishaw JD, Lefkowitz RJ.
    Proc Natl Acad Sci U S A; 1997 Mar 18; 94(6):2180-5. PubMed ID: 9122168
    [Abstract] [Full Text] [Related]

  • 15. MAPK-dependent degradation of G protein-coupled receptor kinase 2.
    Elorza A, Penela P, Sarnago S, Mayor F.
    J Biol Chem; 2003 Aug 01; 278(31):29164-73. PubMed ID: 12738776
    [Abstract] [Full Text] [Related]

  • 16. The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor β (PDGFRβ) Internalization and Signaling.
    Rorsman C, Tsioumpekou M, Heldin CH, Lennartsson J.
    J Biol Chem; 2016 May 27; 291(22):11608-18. PubMed ID: 27048651
    [Abstract] [Full Text] [Related]

  • 17. Beta 2-adrenergic receptor stimulated, G protein-coupled receptor kinase 2 mediated, phosphorylation of ribosomal protein P2.
    Freeman JL, Gonzalo P, Pitcher JA, Claing A, Lavergne JP, Reboud JP, Lefkowitz RJ.
    Biochemistry; 2002 Oct 22; 41(42):12850-7. PubMed ID: 12379128
    [Abstract] [Full Text] [Related]

  • 18. Tyrosine phosphorylation of G-protein-coupled-receptor kinase 2 (GRK2) by c-Src modulates its interaction with Galphaq.
    Mariggiò S, García-Hoz C, Sarnago S, De Blasi A, Mayor F, Ribas C.
    Cell Signal; 2006 Nov 22; 18(11):2004-12. PubMed ID: 16725308
    [Abstract] [Full Text] [Related]

  • 19. Phosphorylation and desensitization of human endothelin A and B receptors. Evidence for G protein-coupled receptor kinase specificity.
    Freedman NJ, Ament AS, Oppermann M, Stoffel RH, Exum ST, Lefkowitz RJ.
    J Biol Chem; 1997 Jul 11; 272(28):17734-43. PubMed ID: 9211925
    [Abstract] [Full Text] [Related]

  • 20. Phosphatidylinositol 4,5-bisphosphate (PIP2)-enhanced G protein-coupled receptor kinase (GRK) activity. Location, structure, and regulation of the PIP2 binding site distinguishes the GRK subfamilies.
    Pitcher JA, Fredericks ZL, Stone WC, Premont RT, Stoffel RH, Koch WJ, Lefkowitz RJ.
    J Biol Chem; 1996 Oct 04; 271(40):24907-13. PubMed ID: 8798768
    [Abstract] [Full Text] [Related]

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