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415 related items for PubMed ID: 15994948

  • 1. Targeted biallelic inactivation of Pten in the mouse prostate leads to prostate cancer accompanied by increased epithelial cell proliferation but not by reduced apoptosis.
    Ma X, Ziel-van der Made AC, Autar B, van der Korput HA, Vermeij M, van Duijn P, Cleutjens KB, de Krijger R, Krimpenfort P, Berns A, van der Kwast TH, Trapman J.
    Cancer Res; 2005 Jul 01; 65(13):5730-9. PubMed ID: 15994948
    [Abstract] [Full Text] [Related]

  • 2. Characterization of Heterogeneous Prostate Tumors in Targeted Pten Knockout Mice.
    Korsten H, Ziel-van der Made AC, van Weerden WM, van der Kwast T, Trapman J, Van Duijn PW.
    PLoS One; 2016 Jul 01; 11(1):e0147500. PubMed ID: 26807730
    [Abstract] [Full Text] [Related]

  • 3. Conditional deletion of the Pten gene in the mouse prostate induces prostatic intraepithelial neoplasms at early ages but a slow progression to prostate tumors.
    Kwak MK, Johnson DT, Zhu C, Lee SH, Ye DW, Luong R, Sun Z.
    PLoS One; 2013 Jul 01; 8(1):e53476. PubMed ID: 23308230
    [Abstract] [Full Text] [Related]

  • 4. Accumulating progenitor cells in the luminal epithelial cell layer are candidate tumor initiating cells in a Pten knockout mouse prostate cancer model.
    Korsten H, Ziel-van der Made A, Ma X, van der Kwast T, Trapman J.
    PLoS One; 2009 May 22; 4(5):e5662. PubMed ID: 19461893
    [Abstract] [Full Text] [Related]

  • 5. Overexpression of the tumor suppressor gene phosphatase and tensin homologue partially inhibits wnt-1-induced mammary tumorigenesis.
    Zhao H, Cui Y, Dupont J, Sun H, Hennighausen L, Yakar S.
    Cancer Res; 2005 Aug 01; 65(15):6864-73. PubMed ID: 16061670
    [Abstract] [Full Text] [Related]

  • 6. Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer.
    Wang S, Gao J, Lei Q, Rozengurt N, Pritchard C, Jiao J, Thomas GV, Li G, Roy-Burman P, Nelson PS, Liu X, Wu H.
    Cancer Cell; 2003 Sep 01; 4(3):209-21. PubMed ID: 14522255
    [Abstract] [Full Text] [Related]

  • 7. Activation of hepatocyte growth factor/MET signaling initiates oncogenic transformation and enhances tumor aggressiveness in the murine prostate.
    Mi J, Hooker E, Balog S, Zeng H, Johnson DT, He Y, Yu EJ, Wu H, Le V, Lee DH, Aldahl J, Gonzalgo ML, Sun Z.
    J Biol Chem; 2018 Dec 28; 293(52):20123-20136. PubMed ID: 30401749
    [Abstract] [Full Text] [Related]

  • 8. Temporally controlled ablation of PTEN in adult mouse prostate epithelium generates a model of invasive prostatic adenocarcinoma.
    Ratnacaram CK, Teletin M, Jiang M, Meng X, Chambon P, Metzger D.
    Proc Natl Acad Sci U S A; 2008 Feb 19; 105(7):2521-6. PubMed ID: 18268330
    [Abstract] [Full Text] [Related]

  • 9. Klf5 deletion promotes Pten deletion-initiated luminal-type mouse prostate tumors through multiple oncogenic signaling pathways.
    Xing C, Ci X, Sun X, Fu X, Zhang Z, Dong EN, Hao ZZ, Dong JT.
    Neoplasia; 2014 Nov 19; 16(11):883-99. PubMed ID: 25425963
    [Abstract] [Full Text] [Related]

  • 10. Novel In Vivo model for combinatorial fluorescence labeling in mouse prostate.
    Fang X, Gyabaah K, Nickkholgh B, Cline JM, Balaji KC.
    Prostate; 2015 Jun 15; 75(9):988-1000. PubMed ID: 25753731
    [Abstract] [Full Text] [Related]

  • 11. The influence of growth hormone/insulin-like growth factor deficiency on prostatic dysplasia in pbARR2-Cre, PTEN knockout mice.
    Takahara K, Ibuki N, Ghaffari M, Tearle H, Ong CJ, Azuma H, Gleave ME, Pollak M, Cox ME.
    Prostate Cancer Prostatic Dis; 2013 Sep 15; 16(3):239-47. PubMed ID: 23689346
    [Abstract] [Full Text] [Related]

  • 12. Modulation of epithelial neoplasia and lymphoid hyperplasia in PTEN+/- mice by the p85 regulatory subunits of phosphoinositide 3-kinase.
    Luo J, Sobkiw CL, Logsdon NM, Watt JM, Signoretti S, O'Connell F, Shin E, Shim Y, Pao L, Neel BG, Depinho RA, Loda M, Cantley LC.
    Proc Natl Acad Sci U S A; 2005 Jul 19; 102(29):10238-43. PubMed ID: 16006513
    [Abstract] [Full Text] [Related]

  • 13. PTEN deficiency is fully penetrant for prostate adenocarcinoma in C57BL/6 mice via mTOR-dependent growth.
    Blando J, Portis M, Benavides F, Alexander A, Mills G, Dave B, Conti CJ, Kim J, Walker CL.
    Am J Pathol; 2009 May 19; 174(5):1869-79. PubMed ID: 19395652
    [Abstract] [Full Text] [Related]

  • 14. Cooperation between FGF8b overexpression and PTEN deficiency in prostate tumorigenesis.
    Zhong C, Saribekyan G, Liao CP, Cohen MB, Roy-Burman P.
    Cancer Res; 2006 Feb 15; 66(4):2188-94. PubMed ID: 16489020
    [Abstract] [Full Text] [Related]

  • 15. The pace of prostatic intraepithelial neoplasia development is determined by the timing of Pten tumor suppressor gene excision.
    Luchman HA, Benediktsson H, Villemaire ML, Peterson AC, Jirik FR.
    PLoS One; 2008 Feb 15; 3(12):e3940. PubMed ID: 19081794
    [Abstract] [Full Text] [Related]

  • 16. Signal transduction pathways in androgen-dependent and -independent prostate cancer cell proliferation.
    Ghosh PM, Malik SN, Bedolla RG, Wang Y, Mikhailova M, Prihoda TJ, Troyer DA, Kreisberg JI.
    Endocr Relat Cancer; 2005 Mar 15; 12(1):119-34. PubMed ID: 15788644
    [Abstract] [Full Text] [Related]

  • 17. Depletion of SAG/RBX2 E3 ubiquitin ligase suppresses prostate tumorigenesis via inactivation of the PI3K/AKT/mTOR axis.
    Tan M, Xu J, Siddiqui J, Feng F, Sun Y.
    Mol Cancer; 2016 Dec 12; 15(1):81. PubMed ID: 27955654
    [Abstract] [Full Text] [Related]

  • 18. Akt regulates COX-2 mRNA and protein expression in mutated-PTEN human endometrial cancer cells.
    St-Germain ME, Gagnon V, Mathieu I, Parent S, Asselin E.
    Int J Oncol; 2004 May 12; 24(5):1311-24. PubMed ID: 15067356
    [Abstract] [Full Text] [Related]

  • 19. Conditionally ablated Pten in prostate basal cells promotes basal-to-luminal differentiation and causes invasive prostate cancer in mice.
    Lu TL, Huang YF, You LR, Chao NC, Su FY, Chang JL, Chen CM.
    Am J Pathol; 2013 Mar 12; 182(3):975-91. PubMed ID: 23313138
    [Abstract] [Full Text] [Related]

  • 20. Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis.
    Kim MJ, Cardiff RD, Desai N, Banach-Petrosky WA, Parsons R, Shen MM, Abate-Shen C.
    Proc Natl Acad Sci U S A; 2002 Mar 05; 99(5):2884-9. PubMed ID: 11854455
    [Abstract] [Full Text] [Related]

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