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Journal Abstract Search

201 related items for PubMed ID: 15998293

  • 1. Syntaxin 5 interacts specifically with presenilin holoproteins and affects processing of betaAPP in neuronal cells.
    Suga K, Saito A, Tomiyama T, Mori H, Akagawa K.
    J Neurochem; 2005 Jul; 94(2):425-39. PubMed ID: 15998293
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  • 2. Syntaxin 5 interacts with presenilin holoproteins, but not with their N- or C-terminal fragments, and affects beta-amyloid peptide production.
    Suga K, Tomiyama T, Mori H, Akagawa K.
    Biochem J; 2004 Aug 01; 381(Pt 3):619-28. PubMed ID: 15109302
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  • 3. PEN-2 enhances gamma-cleavage after presenilin heterodimer formation.
    Shiraishi H, Sai X, Wang HQ, Maeda Y, Kurono Y, Nishimura M, Yanagisawa K, Komano H.
    J Neurochem; 2004 Sep 01; 90(6):1402-13. PubMed ID: 15341524
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  • 4. APPepsilon, the epsilon-secretase-derived N-terminal product of the beta-amyloid precursor protein, behaves as a type I protein and undergoes alpha-, beta-, and gamma-secretase cleavages.
    Lefranc-Jullien S, Sunyach C, Checler F.
    J Neurochem; 2006 May 01; 97(3):807-17. PubMed ID: 16524370
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  • 5. Apolipoprotein E modulates gamma-secretase cleavage of the amyloid precursor protein.
    Irizarry MC, Deng A, Lleo A, Berezovska O, Von Arnim CA, Martin-Rehrmann M, Manelli A, LaDu MJ, Hyman BT, Rebeck GW.
    J Neurochem; 2004 Sep 01; 90(5):1132-43. PubMed ID: 15312168
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  • 7. Presenilin 1 is involved in the maturation of beta-site amyloid precursor protein-cleaving enzyme 1 (BACE1).
    Kuzuya A, Uemura K, Kitagawa N, Aoyagi N, Kihara T, Ninomiya H, Ishiura S, Takahashi R, Shimohama S.
    J Neurosci Res; 2007 Jan 01; 85(1):153-65. PubMed ID: 17075903
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  • 8. Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms.
    Bentahir M, Nyabi O, Verhamme J, Tolia A, Horré K, Wiltfang J, Esselmann H, De Strooper B.
    J Neurochem; 2006 Feb 01; 96(3):732-42. PubMed ID: 16405513
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  • 9. Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: implications for Alzheimer's disease.
    Mohmmad Abdul H, Sultana R, Keller JN, St Clair DK, Markesbery WR, Butterfield DA.
    J Neurochem; 2006 Mar 01; 96(5):1322-35. PubMed ID: 16478525
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  • 10. Proprotein convertase activity contributes to the processing of the Alzheimer's beta-amyloid precursor protein in human cells: evidence for a role of the prohormone convertase PC7 in the constitutive alpha-secretase pathway.
    Lopez-Perez E, Seidah NG, Checler F.
    J Neurochem; 1999 Nov 01; 73(5):2056-62. PubMed ID: 10537065
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  • 13. Presenilin-1-mediated retention of APP derivatives in early biosynthetic compartments.
    Réchards M, Xia W, Oorschot V, van Dijk S, Annaert W, Selkoe DJ, Klumperman J.
    Traffic; 2006 Mar 01; 7(3):354-64. PubMed ID: 16497228
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  • 16. Co-expressed presenilin 1 NTF and CTF form functional gamma-secretase complexes in cells devoid of full-length protein.
    Laudon H, Mathews PM, Karlström H, Bergman A, Farmery MR, Nixon RA, Winblad B, Gandy SE, Lendahl U, Lundkvist J, Näslund J.
    J Neurochem; 2004 Apr 01; 89(1):44-53. PubMed ID: 15030388
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  • 17. BACE1 inhibition reduces endogenous Abeta and alters APP processing in wild-type mice.
    Nishitomi K, Sakaguchi G, Horikoshi Y, Gray AJ, Maeda M, Hirata-Fukae C, Becker AG, Hosono M, Sakaguchi I, Minami SS, Nakajima Y, Li HF, Takeyama C, Kihara T, Ota A, Wong PC, Aisen PS, Kato A, Kinoshita N, Matsuoka Y.
    J Neurochem; 2006 Dec 01; 99(6):1555-63. PubMed ID: 17083447
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  • 18. C-terminal PAL motif of presenilin and presenilin homologues required for normal active site conformation.
    Wang J, Beher D, Nyborg AC, Shearman MS, Golde TE, Goate A.
    J Neurochem; 2006 Jan 01; 96(1):218-27. PubMed ID: 16305624
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  • 20. Gamma-secretase subunit composition and distribution in the presenilin wild-type and mutant mouse brain.
    Siman R, Salidas S.
    Neuroscience; 2004 Jan 01; 129(3):615-28. PubMed ID: 15541883
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