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Journal Abstract Search

579 related items for PubMed ID: 1600620

  • 1. Participation of rat liver cytochrome P450 2E1 in the activation of N-nitrosodimethylamine and N-nitrosodiethylamine to products genotoxic in an acetyltransferase-overexpressing Salmonella typhimurium strain (NM2009).
    Yamazaki H, Oda Y, Funae Y, Imaoka S, Inui Y, Guengerich FP, Shimada T.
    Carcinogenesis; 1992 Jun; 13(6):979-85. PubMed ID: 1600620
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  • 2. Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes.
    Yamazaki H, Inui Y, Yun CH, Guengerich FP, Shimada T.
    Carcinogenesis; 1992 Oct; 13(10):1789-94. PubMed ID: 1423839
    [Abstract] [Full Text] [Related]

  • 3. Activation of 6-aminochrysene to genotoxic products by different forms of rat liver cytochrome P450 in an O-acetyltransferase-overexpressing Salmonella typhimurium strain (NM2009).
    Yamazaki H, Shimada T.
    Biochem Pharmacol; 1992 Sep 01; 44(5):913-20. PubMed ID: 1530660
    [Abstract] [Full Text] [Related]

  • 4. Use of a newly developed tester strain Salmonella typhimurium NM2009 for the study of metabolic activation of carcinogenic aromatic amines by rat liver microsomal cytochrome P-450 enzymes.
    Yamazaki H, Oda Y, Shimada T.
    Mutat Res; 1992 Oct 01; 272(2):183-92. PubMed ID: 1383750
    [Abstract] [Full Text] [Related]

  • 5. High variability of nitrosamine metabolism among individuals: role of cytochromes P450 2A6 and 2E1 in the dealkylation of N-nitrosodimethylamine and N-nitrosodiethylamine in mice and humans.
    Camus AM, Geneste O, Honkakoski P, Béréziat JC, Henderson CJ, Wolf CR, Bartsch H, Lang MA.
    Mol Carcinog; 1993 Oct 01; 7(4):268-75. PubMed ID: 8352885
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  • 6. Requirements for cytochrome b5 in the oxidation of 7-ethoxycoumarin, chlorzoxazone, aniline, and N-nitrosodimethylamine by recombinant cytochrome P450 2E1 and by human liver microsomes.
    Yamazaki H, Nakano M, Gillam EM, Bell LC, Guengerich FP, Shimada T.
    Biochem Pharmacol; 1996 Jul 26; 52(2):301-9. PubMed ID: 8694855
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  • 8. Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes.
    Yamazaki H, Mimura M, Oda Y, Inui Y, Shiraga T, Iwasaki K, Guengerich FP, Shimada T.
    Carcinogenesis; 1993 Jul 26; 14(7):1271-8. PubMed ID: 8330339
    [Abstract] [Full Text] [Related]

  • 9. Development of high sensitive umu test system: rapid detection of genotoxicity of promutagenic aromatic amines by Salmonella typhimurium strain NM2009 possessing high O-acetyltransferase activity.
    Oda Y, Yamazaki H, Watanabe M, Nohmi T, Shimada T.
    Mutat Res; 1995 Apr 26; 334(2):145-56. PubMed ID: 7885366
    [Abstract] [Full Text] [Related]

  • 10. Activation of trans-1,2-dihydro-1,2-dihydroxy-6-aminochrysene to genotoxic metabolites by rat and human cytochromes P450.
    Yamazaki H, Mimura M, Oda Y, Gonzalez FJ, el-Bayoumy K, Chae YH, Guengerich FP, Shimada T.
    Carcinogenesis; 1994 Mar 26; 15(3):465-70. PubMed ID: 8118930
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  • 11. Metabolic activation of carcinogenic 1-nitropyrene by human cytochrome P450 1B1 in Salmonella typhimurium strain expressing an O-acetyltransferase in SOS/umu assay.
    Hatanaka N, Yamazaki H, Oda Y, Guengerich FP, Nakajima M, Yokoi T.
    Mutat Res; 2001 Oct 18; 497(1-2):223-33. PubMed ID: 11525925
    [Abstract] [Full Text] [Related]

  • 12. Enzymatic mechanisms in the metabolic activation of N-nitrosodialkylamines.
    Yang CS, Patten C, Lee MJ, Li M, Yoo JS, Pan J, Hong J.
    IARC Sci Publ; 1987 Oct 18; (84):104-8. PubMed ID: 3679343
    [Abstract] [Full Text] [Related]

  • 13. Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase.
    Oda Y, Aryal P, Terashita T, Gillam EM, Guengerich FP, Shimada T.
    Mutat Res; 2001 May 31; 492(1-2):81-90. PubMed ID: 11377247
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  • 15. Genotoxic activation of 2-phenylbenzotriazole-type compounds by human cytochrome P4501A1 and N-acetyltransferase expressed in Salmonella typhimurium umu strains.
    Oda Y, Watanabe T, Terao Y, Nukaya H, Wakabayashi K.
    Mutat Res; 2008 Jun 30; 654(1):52-7. PubMed ID: 18562244
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  • 17. Alkylation of cellular macromolecules and target specificity of carcinogenic nitrosodialkylamines: metabolic activation by cytochromes P450 2B1 and 2E1.
    Shu L, Hollenberg PF.
    Carcinogenesis; 1997 Apr 30; 18(4):801-10. PubMed ID: 9111218
    [Abstract] [Full Text] [Related]

  • 18. Genotoxic activation of the environmental pollutant 3,6-dinitrobenzo[e]pyrene in Salmonella typhimurium umu strains expressing human cytochrome P450 and N-acetyltransferase.
    Oda Y, Hirayama T, Watanabe T.
    Toxicol Lett; 2009 Aug 10; 188(3):258-62. PubMed ID: 19393727
    [Abstract] [Full Text] [Related]

  • 19. Contribution of DNA methylation and benzylation to N-nitroso-N-benzyl-methylamine-induced mutagenesis in bacteria: effects of rat liver cytochrome P450 isozymes and glutathione transferases.
    Lin DX, Malaveille C, Park SS, Gelboin HV, Bartsch H.
    Carcinogenesis; 1990 Sep 10; 11(9):1653-8. PubMed ID: 2119260
    [Abstract] [Full Text] [Related]

  • 20. Heterologous expression of rat P450 2E1 in a mammalian cell line: in situ metabolism and cytotoxicity of N-nitrosodimethylamine.
    Lin HL, Roberts ES, Hollenberg PF.
    Carcinogenesis; 1998 Feb 10; 19(2):321-9. PubMed ID: 9498284
    [Abstract] [Full Text] [Related]

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