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Journal Abstract Search

374 related items for PubMed ID: 16007118

  • 1. Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer.
    Oliveira C, Velho S, Domingo E, Preto A, Hofstra RM, Hamelin R, Yamamoto H, Seruca R, Schwartz S.
    Oncogene; 2005 Nov 17; 24(51):7630-4. PubMed ID: 16007118
    [Abstract] [Full Text] [Related]

  • 2. Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation.
    Nagasaka T, Sasamoto H, Notohara K, Cullings HM, Takeda M, Kimura K, Kambara T, MacPhee DG, Young J, Leggett BA, Jass JR, Tanaka N, Matsubara N.
    J Clin Oncol; 2004 Nov 15; 22(22):4584-94. PubMed ID: 15542810
    [Abstract] [Full Text] [Related]

  • 3. Inverse correlation between RASSF1A hypermethylation, KRAS and BRAF mutations in cervical adenocarcinoma.
    Kang S, Kim HS, Seo SS, Park SY, Sidransky D, Dong SM.
    Gynecol Oncol; 2007 Jun 15; 105(3):662-6. PubMed ID: 17360030
    [Abstract] [Full Text] [Related]

  • 4. RASSF1A hypermethylation and its inverse correlation with BRAF and/or KRAS mutations in MSI-associated endometrial carcinoma.
    Kang S, Lee JM, Jeon ES, Lee S, Kim H, Kim HS, Seo SS, Park SY, Sidransky D, Dong SM.
    Int J Cancer; 2006 Sep 15; 119(6):1316-21. PubMed ID: 16619251
    [Abstract] [Full Text] [Related]

  • 5. Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status.
    Oliveira C, Westra JL, Arango D, Ollikainen M, Domingo E, Ferreira A, Velho S, Niessen R, Lagerstedt K, Alhopuro P, Laiho P, Veiga I, Teixeira MR, Ligtenberg M, Kleibeuker JH, Sijmons RH, Plukker JT, Imai K, Lage P, Hamelin R, Albuquerque C, Schwartz S, Lindblom A, Peltomaki P, Yamamoto H, Aaltonen LA, Seruca R, Hofstra RM.
    Hum Mol Genet; 2004 Oct 01; 13(19):2303-11. PubMed ID: 15294875
    [Abstract] [Full Text] [Related]

  • 6. Promoter hypermethylation frequency and BRAF mutations distinguish hereditary non-polyposis colon cancer from sporadic MSI-H colon cancer.
    McGivern A, Wynter CV, Whitehall VL, Kambara T, Spring KJ, Walsh MD, Barker MA, Arnold S, Simms LA, Leggett BA, Young J, Jass JR.
    Fam Cancer; 2004 Oct 01; 3(2):101-7. PubMed ID: 15340260
    [Abstract] [Full Text] [Related]

  • 7. K-ras mutations and RASSF1A promoter methylation in colorectal cancer.
    van Engeland M, Roemen GM, Brink M, Pachen MM, Weijenberg MP, de Bruïne AP, Arends JW, van den Brandt PA, de Goeij AF, Herman JG.
    Oncogene; 2002 May 23; 21(23):3792-5. PubMed ID: 12032847
    [Abstract] [Full Text] [Related]

  • 8. BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations.
    Preto A, Figueiredo J, Velho S, Ribeiro AS, Soares P, Oliveira C, Seruca R.
    J Pathol; 2008 Feb 23; 214(3):320-7. PubMed ID: 18098337
    [Abstract] [Full Text] [Related]

  • 9. KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression.
    Oliveira C, Velho S, Moutinho C, Ferreira A, Preto A, Domingo E, Capelinha AF, Duval A, Hamelin R, Machado JC, Schwartz S, Carneiro F, Seruca R.
    Oncogene; 2007 Jan 04; 26(1):158-63. PubMed ID: 16953233
    [Abstract] [Full Text] [Related]

  • 10. BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis?
    Velho S, Moutinho C, Cirnes L, Albuquerque C, Hamelin R, Schmitt F, Carneiro F, Oliveira C, Seruca R.
    BMC Cancer; 2008 Sep 09; 8():255. PubMed ID: 18782444
    [Abstract] [Full Text] [Related]

  • 11. Frequent involvement of ras-signalling pathways in both polypoid-type and flat-type early-stage colorectal cancers.
    Noda H, Kato Y, Yoshikawa H, Arai M, Togashi K, Nagai H, Konishi F, Miki Y.
    J Exp Clin Cancer Res; 2006 Jun 09; 25(2):235-42. PubMed ID: 16918136
    [Abstract] [Full Text] [Related]

  • 12. Mutations of BRAF are associated with extensive hMLH1 promoter methylation in sporadic colorectal carcinomas.
    Koinuma K, Shitoh K, Miyakura Y, Furukawa T, Yamashita Y, Ota J, Ohki R, Choi YL, Wada T, Konishi F, Nagai H, Mano H.
    Int J Cancer; 2004 Jan 10; 108(2):237-42. PubMed ID: 14639609
    [Abstract] [Full Text] [Related]

  • 13. The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer.
    Goel A, Nagasaka T, Arnold CN, Inoue T, Hamilton C, Niedzwiecki D, Compton C, Mayer RJ, Goldberg R, Bertagnolli MM, Boland CR.
    Gastroenterology; 2007 Jan 10; 132(1):127-38. PubMed ID: 17087942
    [Abstract] [Full Text] [Related]

  • 14. BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing.
    Domingo E, Laiho P, Ollikainen M, Pinto M, Wang L, French AJ, Westra J, Frebourg T, Espín E, Armengol M, Hamelin R, Yamamoto H, Hofstra RM, Seruca R, Lindblom A, Peltomäki P, Thibodeau SN, Aaltonen LA, Schwartz S.
    J Med Genet; 2004 Sep 10; 41(9):664-8. PubMed ID: 15342696
    [Abstract] [Full Text] [Related]

  • 15. [A new quantitative DNA-methylation analysis of MSI colorectal cancers helps to separate sporadic colorectal cancers from HNPCC-candidates].
    Bettstetter M, Rümmele P, Hofstädter F, Dietmaier W.
    Verh Dtsch Ges Pathol; 2006 Sep 10; 90():236-43. PubMed ID: 17867602
    [Abstract] [Full Text] [Related]

  • 16. Exon 3 beta-catenin mutations are specifically associated with colorectal carcinomas in hereditary non-polyposis colorectal cancer syndrome.
    Johnson V, Volikos E, Halford SE, Eftekhar Sadat ET, Popat S, Talbot I, Truninger K, Martin J, Jass J, Houlston R, Atkin W, Tomlinson IP, Silver AR.
    Gut; 2005 Feb 10; 54(2):264-7. PubMed ID: 15647192
    [Abstract] [Full Text] [Related]

  • 17. Integrated analysis of chromosomal, microsatellite and epigenetic instability in colorectal cancer identifies specific associations between promoter methylation of pivotal tumour suppressor and DNA repair genes and specific chromosomal alterations.
    Derks S, Postma C, Carvalho B, van den Bosch SM, Moerkerk PT, Herman JG, Weijenberg MP, de Bruïne AP, Meijer GA, van Engeland M.
    Carcinogenesis; 2008 Feb 10; 29(2):434-9. PubMed ID: 18048385
    [Abstract] [Full Text] [Related]

  • 18. Promoter methylation of TGFbeta receptor I and mutation of TGFbeta receptor II are frequent events in MSI sporadic gastric carcinomas.
    Pinto M, Oliveira C, Cirnes L, Carlos Machado J, Ramires M, Nogueira A, Carneiro F, Seruca R.
    J Pathol; 2003 May 10; 200(1):32-8. PubMed ID: 12692838
    [Abstract] [Full Text] [Related]

  • 19. Methylation of the hMLH1 and hMSH2 promoter in early-onset sporadic colorectal carcinomas with microsatellite instability.
    Kim HC, Kim CN, Yu CS, Roh SA, Kim JC.
    Int J Colorectal Dis; 2003 May 10; 18(3):196-202. PubMed ID: 12673483
    [Abstract] [Full Text] [Related]

  • 20. BRAF/K-ras mutation, microsatellite instability, and promoter hypermethylation of hMLH1/MGMT in human gastric carcinomas.
    Wu M, Semba S, Oue N, Ikehara N, Yasui W, Yokozaki H.
    Gastric Cancer; 2004 May 10; 7(4):246-53. PubMed ID: 15616773
    [Abstract] [Full Text] [Related]

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