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496 related items for PubMed ID: 16014567

  • 1. Tachpyridine, a metal chelator, induces G2 cell-cycle arrest, activates checkpoint kinases, and sensitizes cells to ionizing radiation.
    Turner J, Koumenis C, Kute TE, Planalp RP, Brechbiel MW, Beardsley D, Cody B, Brown KD, Torti FM, Torti SV.
    Blood; 2005 Nov 01; 106(9):3191-9. PubMed ID: 16014567
    [Abstract] [Full Text] [Related]

  • 2. Cadmium-induced DNA damage triggers G(2)/M arrest via chk1/2 and cdc2 in p53-deficient kidney proximal tubule cells.
    Bork U, Lee WK, Kuchler A, Dittmar T, Thévenod F.
    Am J Physiol Renal Physiol; 2010 Feb 01; 298(2):F255-65. PubMed ID: 19923412
    [Abstract] [Full Text] [Related]

  • 3. Irradiation-induced G2/M checkpoint response requires ERK1/2 activation.
    Yan Y, Black CP, Cowan KH.
    Oncogene; 2007 Jul 12; 26(32):4689-98. PubMed ID: 17297454
    [Abstract] [Full Text] [Related]

  • 4. Caffeine inhibits checkpoint responses without inhibiting the ataxia-telangiectasia-mutated (ATM) and ATM- and Rad3-related (ATR) protein kinases.
    Cortez D.
    J Biol Chem; 2003 Sep 26; 278(39):37139-45. PubMed ID: 12847089
    [Abstract] [Full Text] [Related]

  • 5. Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.
    Lossaint G, Besnard E, Fisher D, Piette J, Dulić V.
    Oncogene; 2011 Oct 13; 30(41):4261-74. PubMed ID: 21532626
    [Abstract] [Full Text] [Related]

  • 6. Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.
    Gatei M, Sloper K, Sorensen C, Syljuäsen R, Falck J, Hobson K, Savage K, Lukas J, Zhou BB, Bartek J, Khanna KK.
    J Biol Chem; 2003 Apr 25; 278(17):14806-11. PubMed ID: 12588868
    [Abstract] [Full Text] [Related]

  • 7. Mice lacking protein phosphatase 5 are defective in ataxia telangiectasia mutated (ATM)-mediated cell cycle arrest.
    Yong W, Bao S, Chen H, Li D, Sánchez ER, Shou W.
    J Biol Chem; 2007 May 18; 282(20):14690-4. PubMed ID: 17376776
    [Abstract] [Full Text] [Related]

  • 8. ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling.
    Stiff T, Walker SA, Cerosaletti K, Goodarzi AA, Petermann E, Concannon P, O'Driscoll M, Jeggo PA.
    EMBO J; 2006 Dec 13; 25(24):5775-82. PubMed ID: 17124492
    [Abstract] [Full Text] [Related]

  • 9. UCN-01 inhibits p53 up-regulation and abrogates gamma-radiation-induced G(2)-M checkpoint independently of p53 by targeting both of the checkpoint kinases, Chk2 and Chk1.
    Yu Q, La Rose J, Zhang H, Takemura H, Kohn KW, Pommier Y.
    Cancer Res; 2002 Oct 15; 62(20):5743-8. PubMed ID: 12384533
    [Abstract] [Full Text] [Related]

  • 10. Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage.
    Helt CE, Cliby WA, Keng PC, Bambara RA, O'Reilly MA.
    J Biol Chem; 2005 Jan 14; 280(2):1186-92. PubMed ID: 15533933
    [Abstract] [Full Text] [Related]

  • 11. p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage.
    Reinhardt HC, Aslanian AS, Lees JA, Yaffe MB.
    Cancer Cell; 2007 Feb 14; 11(2):175-89. PubMed ID: 17292828
    [Abstract] [Full Text] [Related]

  • 12. Bendamustine induces G2 cell cycle arrest and apoptosis in myeloma cells: the role of ATM-Chk2-Cdc25A and ATM-p53-p21-pathways.
    Gaul L, Mandl-Weber S, Baumann P, Emmerich B, Schmidmaier R.
    J Cancer Res Clin Oncol; 2008 Feb 14; 134(2):245-53. PubMed ID: 17653574
    [Abstract] [Full Text] [Related]

  • 13. 4-Hydroxynonenal induces G2/M phase cell cycle arrest by activation of the ataxia telangiectasia mutated and Rad3-related protein (ATR)/checkpoint kinase 1 (Chk1) signaling pathway.
    Chaudhary P, Sharma R, Sahu M, Vishwanatha JK, Awasthi S, Awasthi YC.
    J Biol Chem; 2013 Jul 12; 288(28):20532-46. PubMed ID: 23733185
    [Abstract] [Full Text] [Related]

  • 14. Dissecting cellular responses to irradiation via targeted disruptions of the ATM-CHK1-PP2A circuit.
    Palii SS, Cui Y, Innes CL, Paules RS.
    Cell Cycle; 2013 Apr 01; 12(7):1105-18. PubMed ID: 23462183
    [Abstract] [Full Text] [Related]

  • 15. Three independent mechanisms for arrest in G2 after ionizing radiation.
    Landsverk KS, Patzke S, Rein ID, Stokke C, Lyng H, De Angelis PM, Stokke T.
    Cell Cycle; 2011 Mar 01; 10(5):819-29. PubMed ID: 21325885
    [Abstract] [Full Text] [Related]

  • 16. Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells.
    Tyagi A, Singh RP, Agarwal C, Siriwardana S, Sclafani RA, Agarwal R.
    Carcinogenesis; 2005 Nov 01; 26(11):1978-87. PubMed ID: 15975956
    [Abstract] [Full Text] [Related]

  • 17. DNA damage induced by temozolomide signals to both ATM and ATR: role of the mismatch repair system.
    Caporali S, Falcinelli S, Starace G, Russo MT, Bonmassar E, Jiricny J, D'Atri S.
    Mol Pharmacol; 2004 Sep 01; 66(3):478-91. PubMed ID: 15322239
    [Abstract] [Full Text] [Related]

  • 18. RAC1 GTPase plays an important role in γ-irradiation induced G2/M checkpoint activation.
    Yan Y, Greer PM, Cao PT, Kolb RH, Cowan KH.
    Breast Cancer Res; 2012 Apr 11; 14(2):R60. PubMed ID: 22494620
    [Abstract] [Full Text] [Related]

  • 19. Elevated cyclin G2 expression intersects with DNA damage checkpoint signaling and is required for a potent G2/M checkpoint arrest response to doxorubicin.
    Zimmermann M, Arachchige-Don AS, Donaldson MS, Dallapiazza RF, Cowan CE, Horne MC.
    J Biol Chem; 2012 Jun 29; 287(27):22838-53. PubMed ID: 22589537
    [Abstract] [Full Text] [Related]

  • 20. Resveratrol analogue (E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl)ethenyl]-quinazoline induces G₂/M cell cycle arrest through the activation of ATM/ATR in human cervical carcinoma HeLa cells.
    Kim JY, Choi HE, Lee HH, Shin JS, Shin DH, Choi JH, Lee YS, Lee KT.
    Oncol Rep; 2015 May 29; 33(5):2639-47. PubMed ID: 25812484
    [Abstract] [Full Text] [Related]

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